Results 231 to 240 of about 484,484 (318)

Successful treatment of generalized pustular psoriasis with chronic hepatitis B using spesolimab: A case report. [PDF]

Medicine (Baltimore)
Ming R, Zhang L, Xiong X.
europepmc   +1 more source

Clinical Evaluation of Potential Interaction Between Bemnifosbuvir and Ruzasvir With an Assessment of Food Effect: Results of a Phase 1 Study in Healthy Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A combination of nucleotide hepatitis C virus (HCV) nonstructural protein (NS) 5B and 5A inhibitors is a preferred standard of care for treating chronic HCV. Bemnifosbuvir is a novel oral guanosine nucleotide prodrug with potent pan‐genotypic inhibitory activity against HCV NS5B.
Xiao‐Jian Zhou, Gaetano Morelli, Maureen Montrond, Shannan Lynch, Keith Pietropaolo, Bruce Belanger, Arantxa Horga, Janet Hammond   +7 more
wiley   +1 more source

Double reflex testing improves the efficacy and cost effectiveness of hepatitis delta diagnosis in southern Spain. [PDF]

Sci Rep
Fuentes A, Estévez-Escobar M, De Salazar A, Escolano ER, Montiel N, Macías M, Alados JC, Aguilar JC, Pérez AB, Baena PB, Cabezas T, Camelo-Castillo A, Palop B, Grande RG, Viciana I, Bandera JMP, Sánchez FF, Lozano MDC, Giráldez Á, Domínguez MDC, Maté CJ, Arellano ER, Cordero P, De Luna FFÁ, Del Pino P, Salgado AI, Pérez D, Sampedro A, Garrido MÁL, Luzón-García MP, Salas-Coronas J, Roldán C, García F, Freyre C, Rodríguez GS, Rosales-Zabal JM, Domínguez-Hernández R, Casado M, García F.   +38 more
europepmc   +1 more source

Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy

ChemPlusChem, EarlyView.
Recent advances in the field of nucleic acid nuclear magnetic resonance (NMR) are presented. Stable isotope labeling protocols and new approaches to segmentally label nucleic acid with NMR‐active residues are summarized. The novel methods will have a strong impact on the future of nucleic acid NMR and the characterization of structure and dynamics of ...
Stefan Hilber, Solomon Kojo Attionu, Theodore Kwaku Dayie, Christoph Kreutz   +3 more
wiley   +1 more source

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima, Yukihiro Sanada, Shinya Otomo, Keiko Ogaki, Taiichi Wakiya, Noriki Okada, Yuta Hirata, Yasuharu Onishi, Yasunaru Sakuma, Yukiyo Wada, Akio Fujimura, Koichi Mizuta   +11 more
wiley   +1 more source

Plasminogen as a Marker for Assessing Thrombotic Risk During Hepatitis in Cameroon: Case-Control Study. [PDF]

Health Sci Rep
Tuono RM, Tchoumke MM, Tepe WAD, Jeuta WK, Fewou SN.   +4 more
europepmc   +1 more source

Populations Addressed in Vaccines Approved via the European Medicines Agency

Clinical Pharmacology &Therapeutics, EarlyView.
Therapeutic and prophylactic agents require robust evidence before patient use. Randomized controlled trials are essential for evaluating safety and efficacy but often exclude specific populations that are also targets for the intervention. This study assessed which populations are included in vaccine registration studies and/or addressed in label ...
Débora D. Gräf, Lukas Westphal, Jonathan Kimmelman, Christine E. Hallgreen   +3 more
wiley   +1 more source

Predicting relapse after achieving a functional cure for chronic hepatitis B (CHB) using baseline HBsAg and end-of-treatment HBsAb levels. [PDF]

Sci Rep
Han L, Wang Z, Kang L, Cui X, Li Y, Yin H, Gao Y, Li J.   +7 more
europepmc   +1 more source

Comparative Evaluation of Simplified and Modified Histologic Criteria in the Diagnosis of Chronic Autoimmune Hepatitis. [PDF]

Adv Biomed Res
Sanei MH, Tamizifar B, Mardani E, Ghaderi A, Tarigholeslami E, Sanei M.   +5 more
europepmc   +1 more source

Rethinking Chlorine: Essential Chemical or Replaceable Risk?

ChemSusChem, EarlyView.
Chlorine is essential for the production of plastics and pharmaceuticals but poses significant safety and environmental risks. Herein, processes are presented that substitute chlorine or reduce its demand. Where indispensable, trichloride‐ and bichloride‐based ionic liquids could enhance safety and streamline the integration of renewable energy ...
Johannes Schwan, Merlin Kleoff, Gesa H. Dreyhsig, Patrick Voßnacker, Traute Fiedler, Marian Rosental, Sebastian Riedel   +6 more
wiley   +1 more source