Results 181 to 190 of about 104,518 (264)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Oropouche virus causes acute hepatitis in mice controlled by type I interferons. [PDF]

J Virol
Sterling CE, Rush RE, McGaughey JJ, Snow BA, Benton AJ, Duprex WP, Amarasinghe GK, Monga SP, Hartman AL.   +8 more
europepmc   +1 more source

Honeysuckle as a Food-Medicine Resource: A Review of Its Multi-Target Pharmacological Effects and Emerging Applications. [PDF]

Molecules
Gao J, Li L, Li Y.
europepmc   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

DNA methylation-mediated suppression of endocytosis confers resistance to duck hepatitis A virus type 3. [PDF]

Microbiol Spectr
Li S, Hu D, Mei X, Kinkpe L, Wang S, Wei J, Hou S, Zhang Y, Wang X.   +8 more
europepmc   +1 more source

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

Portal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

Cross‑kingdom antiviral action of Scutellaria baicalensis Georgi and Chrysanthemum indicum L. miRNAs: A novel strategy against duck viral hepatitis. [PDF]

Poult Sci
Hu M, Chen Z, Wang K, Liu X, Guan S, Fu X, Gu B, Liu X, Yan Z, Liu J.   +9 more
europepmc   +1 more source

Advances in Viral Markers for Predicting Functional Cure of Chronic Hepatitis B

Portal Hypertension &Cirrhosis, EarlyView.
Functional cure, defined as sustained hepatitis B surface antigen (HBsAg) loss, is achieved by only a minority of patients with chronic hepatitis B (CHB); early identification of likely responders may improve cure rates and reduce costs. However, responses to antiviral therapy vary considerably, necessitating reliable hepatitis B virus (HBV) viral ...
Xinrong Lu, Xin Yang, Qishui Ou, Zhen Xun   +3 more
wiley   +1 more source

Preliminary Screening for Selected Viral Pathogens in Red Fox Carcasses from Pisa Province, Italy. [PDF]

Pathogens
Forzan M, Banducci G, Mazzei M, Soares Filipe J, Verin R, Senese M, Cingottini D, Sgorbini M, Parisi F.   +8 more
europepmc   +1 more source

Severe Scrotal Cellulitis in a Young Man

JEADV Clinical Practice, EarlyView.
Hamad El Hajj, Vera Al Baaklini, Dima Jeha, Alfred Ammoury   +3 more
wiley   +1 more source