Results 271 to 280 of about 102,448 (310)

Lessons from the Pathology of Viral Hepatitis in Animal Models

1986
The histogenesis of the various morphologic features in the different types of human viral hepatitis is not established, nor are definite criteria in the histologic distinction agreed upon. Moreover, the mechanism of transition to hepatocellular carcinoma (HCC) is not clarified, including molecular pathobiologic changes.
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PD-1 blockage reverses immune dysfunction and viral persistence to Hepatitis B virus infection in mouse animal model (67.16)

The Journal of Immunology, 2011
Abstract Recent studies in animal models of virus infection, indicate that the interaction between the inhibitory receptor programmed death (PD)-1 on lymphocytes and its ligands plays a critical role in T-cell exhaustion by inducing T-cell inactivation, and high PD-1 expression levels on peripheral T-lymphocytes as well as the ...
Ping-Ning Hsu, Horng-Tay Tzeng, Hsiu-Jung Liao   +2 more
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Melatonin prevents the decreased activity of antioxidant enzymes and activates nuclear erythroid 2‐related factor 2 signaling in an animal model of fulminant hepatic failure of viral origin

Journal of Pineal Research, 2010
Abstract:  This work was undertaken to investigate whether treatment with melatonin prevents oxidative stress and changes in the expression and activity of factor erythroid 2‐related factor 2 (Nrf2)‐mediated antioxidant enzymes in an animal model of fulminant hepatic failure of viral origin.
Irene, Crespo, Beatriz S, Miguel, Almudena, Laliena, Marcelino, Alvarez, Jesús M, Culebras, Javier, González-Gallego, María J, Tuñón   +6 more
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Hepatocellular carcinoma in woodchuck hepatitis virus-infected woodchucks: Presence of viral DNA in tumor tissue from chronic carriers and animals serologically recovered from acute infections

Hepatology, 1989
During long-term studies of the natural history of woodchuck hepatitis virus infection, five cases of histologically confirmed, primary hepatocellular carcinoma were observed in a total of 92 woodchucks which had recovered, by analysis of viral serologic markers (WHsAG−, anti-WHc+, anti-WHs+), from experimental acute woodchuck
B E, Korba, F V, Wells, B, Baldwin, P J, Cote, B C, Tennant, H, Popper, J L, Gerin   +6 more
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The tree shrews: useful animal models for the viral hepatitis and hepatocellular carcinoma.

Hepato-gastroenterology, 2005
Hepatitis B virus (HBV)-induced hepatitis and hepatocellular carcinoma (HCC) are major diseases worldwide. HBV infection and chemical carcinogens such as aflatoxin B1 are known to be two key factors in the development of HCC. Animal models for hepatitis and HCC are very useful in the in vivo studies of mechanism involved in the development and ...
Er-Bin, Yang, Ji, Cao, Jian-Jia, Su, Pierce, Chow   +3 more
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Establishment of enterically transmitted hepatitis virus animal models using lipid nanoparticle-based full-length viral genome RNA delivery system

Gut
Background Enterically transmitted hepatitis viruses, such as hepatitis A virus (HAV) and hepatitis E virus (HEV), remain notable threats to public health. However, stable and reliable animal models of HAV and HEV infection are lacking. Objective
Tianxu Liu, Jian Li, Xin Yin, Fengmin Lu, Hui Zhao, Lin Wang, Cheng-Feng Qin   +6 more
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COMPARATIVE STUDIES ON VIRAL HEPATITIS IN ANIMALS AND IN MAN

Annals of the New York Academy of Sciences, 1958
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Artificial intelligence in animal farming: A systematic literature review

Journal of Cleaner Production, 2022
Qiuju Xie
exaly  

Translating energy balance research from the bench to the clinic to the community: Parallel animal‐human studies in cancer

Ca-A Cancer Journal for Clinicians, 2023
exaly  

[Viral hepatitis in animals].

Revue de pathologie generale et de physiologie clinique, 2002
J, VERGE, P, GORET, A, PARAF, M, FONTAINE   +3 more
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