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Conserved deletion of two consecutive glycine residues in the 100K protein is a critical determinant of FAdV-11 pathogenicity. [PDF]

open access: yesVirulence
Wang B   +15 more
europepmc   +1 more source
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Viral hepatitis, type B, in experimental animals

The American Journal of the Medical Sciences, 1975
Evidence of natural infection with hepatitis B virus (HBV) in chimpanzees was followed by demonstration that this species provides a highly sensitive animal model system for experimental type B hepatitis. With rare exceptions, inoculation of sero-negative chimps with materials containing infectious HBV produces serologic evidence of infection including
L F, Barker   +5 more
openaire   +2 more sources

Cell Culture and Animal Models of Viral Hepatitis. Part I: Hepatitis B

Lab Animal, 2004
Despite the existence of a preventative vaccine, HBV represents a substantial threat to public health, suggesting the need for research to develop new treatments to combat the disease. The authors review the available in vitro and in vivo models, including recently developed transgenic and chimeric mouse models.
Chandan, Guha   +3 more
openaire   +2 more sources

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