Results 11 to 20 of about 243,044 (167)

Molecular Identification of HIV-1 in the Presence of Hepatitis B Virus and Hepatitis C Virus Co-infections

Balkan Medical Journal, 2020
Background: Because of their similar modes of transmission, the simultaneous infection of viral hepatitis and human immunodeficiency virus are increasingly seen as a big problem related to human health. Aims: To determine the drug mutations in hepatitis
Müge Özgüler, Figen Sarıgül Yıldırım, Taner Yıldırmak, Alper Gündüz, Başak Dokuzoğuz, Mustafa Kemal Çelen, Dilara İnan, Yasemin Heper, Gülden Ersöz, İlkay Karaoğlan, Nurgül Ceran, Aydın Deveci, Servet Öztürk, Selda Sayın Kutlu, Hülya Özkan Özdemir, Ayhan Akbulut, Saadet Yazıcı, Alper Şener, Atahan Çağatay, Serhat Ünal   +19 more
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Human genetic basis of fulminant viral hepatitis [PDF]

Human Genetics, 2020
In rare cases, hepatitis A virus (HAV) and hepatitis B virus (HBV) can cause fulminant viral hepatitis (FVH), characterized by massive hepatocyte necrosis and an inflammatory infiltrate. Other viral etiologies of FVH are rarer. FVH is life-threatening, but the patients are typically otherwise healthy, and normally resistant to other microbes.
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An enhancer variant at 16q22.1 predisposes to hepatocellular carcinoma via regulating PRMT7 expression

Nature Communications, 2022
The role of enhancer variants in hepatocellular carcinoma (HCC) predisposition remains unknown. Here, the authors perform a genome-wide survey of HCC-susceptible enhancer variants in 11,958 individuals, identify rs73613962 within the intronic region of ...
Ting Shen, Ting Ni, Jiaxuan Chen, Haitao Chen, Xiaopin Ma, Guangwen Cao, Tianzhi Wu, Haisheng Xie, Bin Zhou, Gang Wei, Hexige Saiyin, Suqin Shen, Peng Yu, Qianyi Xiao, Hui Liu, Yuzheng Gao, Xidai Long, Jianhua Yin, Yanfang Guo, Jiaxue Wu, Gong-Hong Wei, Jinlin Hou, De-Ke Jiang   +22 more
doaj   +1 more source

Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like mtr Efflux Pump Locus

mBio, 2018
Recent reports suggest that mosaic-like sequences within the mtr (multiple transferable resistance) efflux pump locus of Neisseria gonorrhoeae, likely originating from commensal Neisseria sp.
Corinne E. Rouquette-Loughlin, Jennifer L. Reimche, Jacqueline T. Balthazar, Vijaya Dhulipala, Kim M. Gernert, Ellen N. Kersh, Cau D. Pham, Kevin Pettus, A. Jeanine Abrams, David L. Trees, Sancta St Cyr, William M. Shafer   +11 more
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Systematic review of the global epidemiology of viral-induced acute liver failure

BMJ Open, 2020
Objectives The aetiology and burden of viral-induced acute liver failure remains unclear globally. It is important to understand the epidemiology of viral-induced ALF to plan for clinical case management and case prevention.Participants This systematic ...
Rudzani Muloiwa, Jenna Patterson, Hannah Sophia Hussey, Sheetal Silal, Liz Goddard, Mashiko Setshedi, Wendy Spearman, Gregory D Hussey, Benjamin M Kagina   +8 more
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Drugs of Abuse and Their Impact on Viral Pathogenesis

Viruses, 2021
Commonly misused substances such as alcohol, cocaine, heroin, methamphetamine, and opioids suppress immune responses and may impact viral pathogenesis. In recent years, illicit use of opioids has fueled outbreaks of several viral pathogens, including the
Jason T. Blackard, Kenneth E. Sherman
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Mode and tempo of human hepatitis virus evolution

Computational and Structural Biotechnology Journal, 2019
Human viral hepatitis, a major cause of morbidity and mortality worldwide, is caused by highly diverse viruses with different genetic, ecological, and pathogenetic features.
Rachele Cagliani, Diego Forni, Manuela Sironi   +2 more
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Viral hepatitis in patients infected with human immunodeficiency virus [PDF]

Brazilian Journal of Infectious Diseases, 2003
From 1992 to 1995 we studied 232 (69% male, 87% Caucasian) anti-human immunodeficiency virus (anti-HIV) positive Brazilian patients, through a questionnaire; HIV had been acquired sexually by 50%, from blood by 32%, sexually and/or from blood by 16.4% and by an unknown route by 1.7%.
Pavan, Maria Helena P., Aoki, Francisco Hideo, Monteiro, Dinaida Teresa, Gonçales, Neiva Sellan L., Escanhoela, Cecília Amélia F., Gonçales Júnior, Fernando L.   +5 more
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Identification of a Shared Cytochrome p4502E1 Epitope Found in Anesthetic Drug-Induced and Viral Hepatitis

mSphere, 2018
Cytochrome p4502E1 (CYP2E1) autoantibodies are biomarkers for drug-induced hepatitis and chronic hepatitis C. However, major histocompatibility-restricted CYP2E1 epitopes associated with these diseases have not been identified.
Elisa K. McCarthy, Amanda Vakos, Merylin Cottagiri, Joel J. Mantilla, Lakshmi Santhanam, David L. Thomas, L. Mario Amzel, Noel R. Rose, Dolores B. Njoku   +8 more
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Viral Inhibition of the Phytohemagglutinin Response of Human Lymphocytes and Application to Viral Hepatitis

Experimental Biology and Medicine, 1969
SummaryThe PHA-stimulated leukocyte cultures from healthy donors were inoculated with representatives from picornavirus, picodnavirus, arbovirus, myxovirus, paramyxovirus, rhabdovirus, reovirus, adenovirus and papovavirus groups. Cultures were harvested after 6 days of incubation and assayed for virus multiplication and for DNA synthesis of the ...
F T, Willems, J L, Melnick, W E, Rawls
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