Results 21 to 30 of about 243,044 (167)

The potential use of bacteria and bacterial derivatives as drug delivery systems for viral infection

Virology Journal, 2023
Viral infections in humans are responsible for fatalities worldwide and contribute to the incidence of various human ailments. Controllable targeted medicine delivery against many illnesses, including viral infection, may be significantly aided by using ...
Amirhosein Faghihkhorasani, Hanan Hassan Ahmed, Noor Muhammad Mashool, Mariem Alwan, Marjan Assefi, Aya Hussein Adab, Saman Yasamineh, Omid Gholizadeh, Moein Baghani   +8 more
doaj   +1 more source

A human hepatitis B viral enhancer element. [PDF]

The EMBO Journal, 1985
Fragments of the cloned hepatitis B virus (HBV) genome were assayed in vivo for the presence of a transcriptional enhancer element. We demonstrate that sequences positioned approximately 450 bp upstream from the HBcAg gene promoter are required for its efficient activity.
Y, Shaul, W J, Rutter, O, Laub
openaire   +2 more sources

Ultra-long-acting (XLA) antivirals for chronic viral hepatitis

International Journal of Infectious Diseases, 2022
: Viral hepatitis is among the top four causes of mortality globally, causing 1.4 million deaths each year, exceeding tuberculosis, malaria and human immunodeficiency virus. Hepatitis B and C are responsible for 90% of hepatitis deaths, and the remaining
Vicente Soriano, Carmen Alvarez, Benson Edagwa, Carmen de Mendoza, Noemí Montoya, Ana Treviño, Howard Gendelman   +6 more
doaj   +1 more source

Immunohistochemical study of hepatic oval cells in human chronic viral hepatitis

World Journal of Gastroenterology, 2001
To detect immunohistochemically the presence of oval cells in chronic viral hepatitis with antibody against c-kit.We detected oval cells in paraffin embedded liver sections of 3 normal controls and 26 liver samples from patients with chronic viral hepatitis, using immunohistochemistry with antibodies against c-kit, piclass glutathione S-transferase (pi-
X, Ma, D K, Qiu, Y S, Peng
openaire   +2 more sources

Epidemiology of sexually transmitted viral hepatitis in human immunodeficiency virus-positive men who have sex with men in Asia

Journal of the Formosan Medical Association, 2015
Both human immunodeficiency virus (HIV) and viral hepatitis constitute major disease burden globally. As with other parts of the world, the HIV epidemic in Asia impacts mainly on men who have sex with men, one of the at-risk populations for sexually ...
Ada W.C. Lin, Siddharth Sridhar, Ka Hing Wong, Susanna K.P. Lau, Patrick C.Y. Woo   +4 more
doaj   +1 more source

Viral Interference of Hepatitis C and E Virus Replication in Novel Experimental Co-Infection Systems

Cells, 2022
Background: Hepatitis C virus (HCV) constitutes a global health problem, while hepatitis E virus (HEV) is the major cause of acute viral hepatitis globally.
Thomas Burkard, Nora Proske, Kathrin Resner, Laura Collignon, Leonard Knegendorf, Martina Friesland, Lieven Verhoye, Ibrahim M. Sayed, Yannick Brüggemann, Maximilian K. Nocke, Patrick Behrendt, Heiner Wedemeyer, Philip Meuleman, Daniel Todt, Eike Steinmann   +14 more
doaj   +1 more source

Establishment of mice model with human viral hepatitis B

World Journal of Gastroenterology, 2004
To establish a mice model of hepatitis B by using HBV-transgenic mice, and to transfer HBV-specific cytotoxic T lymphocytes (CTL) induced from syngeneic BALB/c mice immunized by a eukaryotic expression vector containing HBV complete genome DNA.HBV DNA was obtained from digested pBR322-2HBV and ligated with the vector pcDNA3.
Li-Fen, Gao, Wen-Sheng, Sun, Chun-Hong, Ma, Su-Xia, Liu, Xiao-Yan, Wang, Li-Ning, Zhang, Ying-Lin, Cao, Fa-Liang, Zhu, Yu-Gang, Liu   +8 more
openaire   +2 more sources

Modest improvement in universal prenatal syphilis screening 5 years after legislation enacted

Pregnancy
Introduction The rate of congenital syphilis increased 498% in Michigan during 2017–2023. Congenital syphilis can be averted if a pregnant woman is screened and treatment initiated ≥30 days before delivery. To strengthen prevention strategies in Michigan,
Jill C. Diesel, Katie Macomber
doaj   +1 more source

Inherited IL-18BP deficiency in human fulminant viral hepatitis [PDF]

Journal of Experimental Medicine, 2019
Fulminant viral hepatitis (FVH) is a devastating and unexplained condition that strikes otherwise healthy individuals during primary infection with common liver-tropic viruses. We report a child who died of FVH upon infection with hepatitis A virus (HAV) at age 11 yr and who was homozygous for a private 40-nucleotide deletion in IL18BP, which encodes ...
Serkan Belkaya, Eleftherios Michailidis, Cecilia B. Korol, Mohammad Kabbani, Aurélie Cobat, Paul Bastard, Yoon Seung Lee, Nicholas Hernandez, Scott Drutman, Ype P. de Jong, Eric Vivier, Julie Bruneau, Vivien Béziat, Bertrand Boisson, Lazaro Lorenzo-Diaz, Soraya Boucherit, Mylène Sebagh, Emmanuel Jacquemin, Jean-François Emile, Laurent Abel, Charles M. Rice, Emmanuelle Jouanguy, Jean-Laurent Casanova   +22 more
openaire   +4 more sources

Making the invisible visible: searching for human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) in Brazilian patients with viral hepatitis B and C

Memorias do Instituto Oswaldo Cruz
With this study, the authors hope to alert clinicians regarding the presence of human T-cell lymphotropic virus type 1 and 2 (HTLV-1/-2) infections in patients with viral hepatitis B and C in Brazil.
Adele Caterino-de-Araujo, Fabiana Aparecida Alves, Karoline Rodrigues Campos, Marcílio Figueiredo Lemos, Regina Célia Moreira   +4 more
doaj   +1 more source