Results 191 to 200 of about 105,845 (307)

Diagnostic Impact of Liver Biopsy Among Antinuclear Antibody Positive Individuals With Mild Liver Enzyme Elevation

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 103-111, July 2026.
In ANA‐positive patients with suspected autoimmune hepatitis (AIH), liver biopsy rarely altered therapeutic management when alanine aminotransferase (ALT) was below 101 U/L and cirrhosis was absent. These findings suggest that biopsy may be safely deferred in this low‐risk group.
David Mehdi Asgher Niazi, Alphonse Charbel, Jan Pfeiffenberger, Uta Merle, Jessica Seessle, Theresa Wenz, Christa Flechtenmacher, Patrick Michl, Conrad Rauber   +8 more
wiley   +1 more source

Considerations for the clinical use of teplizumab in stage 2 Type 1 diabetes: A Consensus Statement from the British Society of Paediatric Endocrinology and Diabetes (BSPED) and the Association of British Clinical Diabetologists (ABCD)

Diabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Introduction In 2025, the Medicines and Healthcare products Regulatory Agency (MHRA) approved the use of teplizumab (a monoclonal anti‐CD3 antibody) to delay progression from Stage 2 to Stage 3 Type 1 diabetes in the UK. Methods To address the need for clear guidance on managing patients eligible for teplizumab therapy, the British Society of ...
Renuka P. Dias, M. Loredana Marcovecchio, Ruben H. Willemsen, Fiona Campbell, Ahmad Ashour, Philip Newland‐Jones, Jennifer Cooper, Parth Narendran, Neil P. Wright   +8 more
wiley   +1 more source

Parental Decline of Newborn Vitamin K and Hepatitis B Vaccine Administration by Newborn Sex.

JAMA Netw Open
Coggins SA, Flannery DD, Mukhopadhyay S, Puopolo KM.   +3 more
europepmc   +1 more source

The T Cell Receptor: Molecular Sensor, Therapeutic Mediator and Probabilistic Driver of Adaptive Immunity

Immunological Reviews, Volume 340, Issue 1, July 2026.
ABSTRACT Advances in high‐throughput sequencing, single‐cell profiling, and genome engineering have transformed the study of T cell receptors (TCRs), enabling the identification and functional interrogation of antigen‐specific repertoires at an unprecedented scale.
Kilian Schober
wiley   +1 more source

Immune Response and Modeled Duration of Protection Following a Single 60 μg Hepatitis B Vaccine Booster in Susceptible Chinese University Students. [PDF]

Vaccines (Basel)
Luo X, Zhou W, Zhou S, Song F, Geng S, Xu H, Cheng Y, Ren M, Dong Y, Lin L, Mao L, Wang B, Chai Y, Miao P, Ma S, Tang J.   +15 more
europepmc   +1 more source

Herpes Simplex Virus Hepatitis: An Overlooked Cause of Acute Liver Failure Across a Broad Spectrum of Immunocompromise

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aims Herpes simplex virus (HSV) infection is common worldwide, but hepatic involvement is rare. HSV hepatitis is an uncommon yet frequently catastrophic cause of acute hepatitis and acute liver failure (ALF), accounting for < 1% of ALF cases while carrying very high mortality when diagnosis and antiviral therapy are delayed ...
Mario U. Mondelli, Serena Ludovisi, Angela Di Matteo, Gülşen Özkaya Şahin, William Irving, European Society of Clinical Microbiology and Infectious Diseases Study Group for Viral Hepatitis (ESGVH)   +5 more
wiley   +1 more source

Hepatitis B vaccine immunity in healthcare workers: Seroprotection and cellular immune signatures of waning response. [PDF]

J Family Med Prim Care
Khargekar NC, Pujari V, Athalye S, Mallik A, Jodhawat N, Shinde S, Banerjee A.   +6 more
europepmc   +1 more source

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4619-4639, July 2026.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska, Dorota Sołtys‐Kalina, Audrey Y.‐H. Teh   +2 more
wiley   +1 more source

Hepatitis B Vaccine Series Completion by 18 Months in Infants Without a Birth Dose.

JAMA Netw Open
Williams JTB, Cruz H, Stein A, Breslin K, Brtnikova M, Crane B, Irving SA, Glenn S, Kenigsberg T, Lewin B, Tartof S, Sundaram ME, Fuller S, Schmidt T, O'Leary S, Canedo D, Glanz JM, DeSilva M, Fuller CC, Zerbo O, Hambidge SJ.   +20 more
europepmc   +1 more source

Immunogenicity and safety in animals of a lyophilized live attenuated hepatitis A vaccine following stabilizer optimization. [PDF]

Sci Rep
Wang Y, Xia Q, Li C, Wu P, Yue L, Wang X, Bai G, Zheng S, Xu Y.   +8 more
europepmc   +1 more source