Results 101 to 110 of about 131,813 (277)

Fighting viral infections and virus-driven tumors with cytotoxic CD4+ T cells [PDF]

open access: yes, 2017
CD4+ T cells have been and are still largely regarded as the orchestrators of immune responses, being able to differentiate into distinct T helper cell populations based on differentiation signals, transcription factor expression, cytokine secretion, and
Adhikary   +229 more
core   +2 more sources

Identification of Clinical Factors Associated With the Immunogenicity of Homologous ChAdOx1‐nCoV‐19 Vaccine in Hemodialysis Patients

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hemodialysis (HD) patients are at higher risk of severe COVID‐19 and may exhibit suboptimal vaccine responses. This study evaluates the factors influencing vaccine‐induced immunity in HD patients following the second dose of the Vaxzevria. A total of 276 HD patients and 126 controls were included. Antibody responses were assessed using binding
Chia‐Wei Chang   +9 more
wiley   +1 more source

Enrollment in YFV Vaccine Trial: An Evaluation of Recruitment Outcomes Associated with a Randomized Controlled Double-Blind Trial of a Live Attenuated Yellow Fever Vaccine

open access: yes, 2013
This investigation evaluated several factors associated with diverse participant enrollment of a clinical trial assessing safety, immunogenicity, and comparative viremia associated with administration of 17-D live, attenuated yellow fever vaccine given ...
Edupuganti, Srilatha   +5 more
core   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen   +11 more
wiley   +1 more source

Strategic evaluations and techno-economic networks. Vaccine innovation in the Cuban biotech sector: for public health – or for profits? [PDF]

open access: yes
In this paper the Cuban biotech sector with its highly integrated vaccine industry is analyzed in the perspective of the techno-economic network model of Michel Callon. The paper discusses the strategic evaluations that have been performed in the sector.
Jens Plahte
core  

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu   +5 more
wiley   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux   +6 more
wiley   +1 more source

Hepatitis B Vaccines. [PDF]

open access: yesJ Infect Dis, 2021
Pattyn J   +3 more
europepmc   +1 more source

Human Papillomavirus: How Social Ideologies Influence Medical Policy and Care [PDF]

open access: yes, 2012
The purpose of this paper is to discuss the ways in which new advances in the production of a vaccine against human papillomavirus (HPV) have been received by both the general public and the medical community.
Hachem, Fadi
core   +1 more source

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