Results 81 to 90 of about 131,813 (277)

A systematic review of the impact of psychosocial factors on immunity: Implications for enhancing BCG response against tuberculosis. [PDF]

, 2019
Background: Tuberculosis (TB) remains an urgent global public health priority, causing 1.5 million deaths worldwide in 2018. There is evidence that psychosocial factors modulate immune function; however, how this may influence TB risk or BCG vaccine ...
Boccia, D, Dowd, JB, Fletcher, H, Hayward, SE, Nellums, LB, Wurie, F   +5 more
core   +2 more sources

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Recent Advances in mRNA-Based Vaccines Against Several Hepatitis Viruses

Biological Procedures Online
Viral hepatitis is a significant danger to global public health as it is the primary cause of mortality worldwide. Hepatitis B virus (HBV), hepatitis C virus (HCV), and hepatitis D virus (HDV) are well-established infectious agents that significantly ...
Rafid Jihad Albadr, Hayder Naji Sameer, Zainab H. Athab, Mohaned Adil, Ahmed Yaseen, Omer Qutaiba B. Allela   +5 more
doaj   +1 more source

Designing the fusion protein of rotavirus VP8 and hepatitis A virus VP1 and evaluating the immunological response in BALB/c mice

Iranian Journal of Microbiology
Background and Objectives: Rotavirus and Hepatitis A virus are responsible for causing gastroenteritis and jaundice. The current vaccination approaches have proven insufficient, especially in low-income countries.
Hassan Yarmohammadi, Mohammadreza Aghasadeghi, Abbas Akhavan Sepahi, Mojtaba Hamidi-fard, Golnaz Bahramali   +4 more
doaj   +1 more source

Modern View on the Problem of Choosing a Vaccine against Hepatitis B

Эпидемиология и вакцинопрофилактика, 2017
The problem of the discrepancy between serotypes of the circulating strains of hepatitis B virus and serotype of the HBsAg in the vaccine is discussed. The results of published scientific studies show that hepatitis B vaccines containing HBsAg serotype ...
V. P. Chulanov, T. A. Semenenko, I. V. Karandashova, S. V. Komarova, D. S. Kostyushev, A. P. Suslov, E. V. Volchkova   +6 more
doaj   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: A randomized controlled trial in non-obese humans [PDF]

, 2016
Calorie restriction (CR) inhibits inflammation and slows aging in many animal species, but in rodents housed in pathogen-free facilities, CR impairs immunity against certain pathogens.
Bhapkar, Manjushri, Das, Sai K, Dixit, Vishwa D, Fontana, Luigi, Fuss, Paul J, Gupta, Alok K, Holloszy, John O, Huang, Megan, Klein, Sam, Lewis, Michael R, Meydani, Simin N, Pieper, Carl F, Roberts, Susan B, Villareal, Dennis T   +13 more
core   +2 more sources

Media‐dependent performance of rabies virus‐like particle production under low oxygen tension in baculovirus‐infected Sf9 cells

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Rabies continues to pose a major public health threat, causing approximately 59 000 deaths each year, especially in regions with limited resources where high costs restrict vaccine access. Safer and scalable vaccine platforms, such as virus‐like particles, are promising alternatives, but their production is highly sensitive to ...
Júlia Públio Rabello, Milena Miyu Teruya, Fernanda Angela Correia Barrence, Thaissa Consoni Bernardino, Jaci Leme, Luis Giovani de Oliveira Guardalini, Noemi Nosomi Taniwaki, Soraia Attie Calil Jorge, Eutimio Gustavo Fernández Núñez   +8 more
wiley   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source