Results 61 to 70 of about 276,512 (289)

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

Analysis of interstitial lung disease in pharmacovigilance databases: Coding challenges and interpretation biases—An update

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Clinically, interstitial lung disease (ILD) is a heterogeneous group of respiratory disorders. Due to their low incidence, pharmacovigilance database analysis is useful to detect them. Precise diagnosis is challenging as well as coding in these databases. Query criteria are among the key elements for a good signal detection.
Romane Freppel   +4 more
wiley   +1 more source

Problems of the Current Vaccination Strategy against Hepatitis B

open access: yesЭпидемиология и вакцинопрофилактика, 2017
Accumulation of escape mutants of hepatitis B virus (HBV) occur in the many countries at the conditions of wide-scale vaccination against hepatitis B, especially among vaccinated children.
M. V. Konopleva   +3 more
doaj   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

The Squalene Oil‐in‐Water Nanoemulsion Vaccine Carrier AddaVax Potentiates TLR‐Induced B‐Cell Responses

open access: yesCytometry Part A, EarlyView.
ABSTRACT For vaccination, the mechanisms of action of antigens and of immunostimulatory pathogen‐associated molecular pattern (PAMP) adjuvants are better understood than the roles of the depot, carrier, and other formulation‐related influences. Here, we carried out cytometric studies of vaccine formulations and the effect of adjuvant formulations on B ...
Egest J. Pone   +3 more
wiley   +1 more source

Review of long term immunogenicity and tolerability of live hepatitis A vaccine

open access: yesHuman Vaccines & Immunotherapeutics, 2020
Hepatitis A represents one of the major public health problems worldwide including India. Vaccination is the most effective way to prevent hepatitis A infection.
N. Shah   +6 more
semanticscholar   +1 more source

Development of polyepitopic immunogenic contrast against hepatitis C virus 1a-6a genotype by in silico approach

open access: yesBiomedical and Biotechnology Research Journal, 2020
Background: Hepatitis C is a viral disease associated with chronic hepatitis and hepatocellular carcinoma. Hepatitis C virus (HCV) plays a critical role in the pathogenesis of this disease.
Zeinab Dehghan   +6 more
doaj   +1 more source

Vaccine coverage and factors associated with vaccine adherence in persons with HIV at an urban infectious disease clinic

open access: yesHuman Vaccines & Immunotherapeutics, 2023
Information on vaccination rates and factors associated with adherence in persons with HIV (PWH) is limited. We report vaccine adherence in 653 adult PWH attending an urban Infectious Disease Clinic from January 2015 to December 2021.
Navina K. Birk   +8 more
doaj   +1 more source

Hepatitis A Vaccine [PDF]

open access: yesNew England Journal of Medicine, 1992
The first effective control measures for the prevention of enterically transmitted viral hepatitis resulted from research conducted during World War II. In 1945, Neefe et al.1 demonstrated that infectious virus could be transmitted by contaminated drinking water, that treatment of the water by filtration and chlorination made it safe to drink, and that
openaire   +3 more sources

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