Results 31 to 40 of about 1,682,836 (306)

Outcomes of hepatitis B immunoglobulin and hepatitis B vaccination in high-risk newborns born to HBeAg-positive mothers

Biomedical Journal, 2022
Background: To evaluate the protective efficacy of a hepatitis B (HB) vaccination program in Taiwan among high-risk children. Methods: Children born to HBeAg-positive mothers from 2001 to 2010 were invited back.
Chen-Hsuan Wu, Wei-Cheng Huang, Chien-Hung Chen, Sheng-Nan Lu   +3 more
doaj   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Acute hepatitis of non-specified etiology

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011
Aim of investigation. To estimate pathogenic and diagnostic value of detection of hepatotropic viruses components (DNA, RNA, antigens) and antiviral immune response at acute hepatitis of non-specified etiology by the methods of enzyme-linked immunoassay (
Ye. V. Tsyganova, O. O. Znoyko, N. D. Yushchuk, K. R. Dudina, M. G. Isagulyants, N. V. Petrakova, T. V. Petrova, M. I. Mikhaylov   +7 more
doaj  

Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate

Nature Communications, 2022
E1E2 spike on the hepatitis C virion is an important target for vaccine design. Here, the authors permute the subunits to generate E2E1 immunogens and show that mosaic nanoparticles displaying different E2E1 antigens elicit cross-neutralizing antibodies ...
Kwinten Sliepen, Laura Radić, Joan Capella-Pujol, Yasunori Watanabe, Ian Zon, Ana Chumbe, Wen-Hsin Lee, Marlon de Gast, Jelle Koopsen, Sylvie Koekkoek, Iván del Moral-Sánchez, Philip J. M. Brouwer, Rashmi Ravichandran, Gabriel Ozorowski, Neil P. King, Andrew B. Ward, Marit J. van Gils, Max Crispin, Janke Schinkel, Rogier W. Sanders   +19 more
doaj   +1 more source

Portable Molecularly Imprinted Polymer Sensor for Rapid Swab‐Based Detection of Norovirus

Advanced Healthcare Materials, EarlyView.
This work reports a rapid, portable smartphone‐based sensor capable of detecting four norovirus genotypes from swab samples within 15 min. Sensor selectivity was validated through evaluation against four common live viruses. The swab‐based sampling process enabled simple sample preparation combined with the compact detection system, supporting use of ...
Amy Dann, Pankaj Singla, Minji Kim, Sloane Stoufer, Clare Thomas, Robert D. Crapnell, Craig E. Banks, Jake McClements, Shayan Seyedin, Mark Geoghegan, Samuel T. Jones, Christopher F. Blanford, Matthew D. Moore, Marloes Peeters   +13 more
wiley   +1 more source

Molecular detection of hepatitis delta virus in blood donors with RT-PCR

Medical Laboratory Journal, 2015
Background and Objective: Hepatitis delta virus is an imperfect virus with RNA and its activity depends on the presence of hepatitis B virus. This virus can lead to acute and chronic diseases in the liver.
Malekpour, B., Tajbakhsh, E, Khamesipour, F, Rahimi, A   +3 more
doaj  

SEQUENCE SIMILARITY BETWEEN THYROID SELF-PROTEIN AND HEPATITIS C VIRUS POLYPROTEIN: possible triggering mechanism of autoimmune thyroiditis

Arquivos de Gastroenterologia
Background - Exposure to viral antigens that share amino acid sequence similar with self- antigens might trigger autoimmune diseases in genetically predisposed individuals, and the molecular mimicry theory suggests that epitope mimicry between the virus ...
Maristella de Araújo Carvalho SOUSA, Raymundo PARANÁ, Luís Jesuíno de Oliveira ANDRADE   +2 more
doaj   +1 more source

Hepatitis B testing practices at a tertiary care centre and their associated costs: A retrospective analysis.

PLoS ONE, 2019
BackgroundHepatitis B is a viral infection requiring specific serologic testing to diagnose the stage of the disease. There are many tests which can be ordered in a variety of combinations.
Alexander Lawandi, Matthew P Cheng, Todd C Lee   +2 more
doaj   +1 more source

Establishment of a yeast-based VLP platform for antigen presentation

Microbial Cell Factories, 2018
Background Chimeric virus-like particles (VLP) allow the display of foreign antigens on their surface and have proved valuable in the development of safe subunit vaccines or drug delivery.
David Wetzel, Theresa Rolf, Manfred Suckow, Andreas Kranz, Andreas Barbian, Jo-Anne Chan, Joachim Leitsch, Michael Weniger, Volker Jenzelewski, Betty Kouskousis, Catherine Palmer, James G. Beeson, Gerhard Schembecker, Juliane Merz, Michael Piontek   +14 more
doaj   +1 more source

INTRAHEPATIC EXPRESSION OF SERUM HEPATITIS VIRUS-ASSOCIATED ANTIGENS

Journal of Experimental Medicine, 1971
SH virus-associated antigens have been identified in the liver and blood by immunofluorescence. This antigenic expression of the hepatitis agent or its genome is found in the cytoplasm of hepatocytes and other cells of the liver.
T. Edgington, D. Ritt
semanticscholar   +1 more source