Results 91 to 100 of about 999,068 (357)

The Prevalence of Hepatitis B Virus Surface Antigen (HBsAg) Variations and Correlation with the Clinical and Serologic Pictures in Chronic Carriers from Khorasan Province, North-East of Iran

Acta Medica Iranica, 2012
This study was designed to determine the correlation of hepatitis B virus surface Ag (HBsAg) variations with the clinical/serological pictures among chronic HBsAg positive patients. The surface gene (S-gene) was amplified and directly sequenced in twenty-
Azam Ghaziasadi, Masoud Ziaee, Mehdi Norouzi, Reza Malekzadeh, Seyed Moayed Alavian, Esmaeil Saberfar, Mohammad Ali Judaki, Shiva Ghamari, Abolfazl Khedive, Alireza Namazi, Ramin Rahimnia, Seyed Mohammad Jazayeri   +11 more
doaj  

Implementing Adult Hepatitis B Immunization and Screening Using Electronic Health Records: A Practical Guide

Vaccines
Importance: Hepatitis B is a serious problem in the United States (US), with up to 2.4 million Americans living with a chronic infection. Only 26–32% of people living with hepatitis B in the US are diagnosed.
H. Nina Kim, Kelly L. Moore, David L. Sanders, Michaela Jackson, Chari Cohen, Richard Andrews, Camilla S. Graham   +6 more
doaj   +1 more source

Surface protein mutations in chronic hepatitis B patients who received hepatitis B vaccine therapy [PDF]

Iranian Journal of Basic Medical Sciences, 2014
Objective (s):The aim of this study was to determine the correlation between vaccine therapy and appearance of mutations in hepatitis B surface antigen (HBsAg)-positive chronic hepatitis B virus (HBV) patients. Materials and Methods: 16 patients received
Maryam Daram, Ghodratollah Montazeri, Hadi Karimzadeh, Reza Malekzadeh, Mahmood Mahmoodi, Zahra Goodarzi, Hossein Keyvani, Shahram Mirmomen, Seyed Moayed Alavian, Michael Roggendorf, Seyed Mohammad Jazayeri   +10 more
doaj  

Asymptomatic Epstein-Barr virus shedding in the urine of kidney transplant recipients: case reports and review of the literature

Infectious Disease Reports, 2017
Epstein-Barr virus (EBV) is associated with a wide range of malignancies and complications like post-transplant lymphoproliferative disorder (PTLD). To suppress active EBV infection in transplant recipients, who are at a heightened risk of developing ...
Maryam Rahbar, Gholamreza Poormand, Masoud Karkhaneh Mahmoodi, Aboozar Jazayeri, Seyed Mohammad Jazayeri   +4 more
doaj   +1 more source

Immunogenicity and Antiviral Response of Therapeutic Hepatitis B Vaccination in a Mouse Model of HBeAg-Negative, Persistent HBV Infection [PDF]

, 2021
Anna D. Kosinska, Julia Festag, Martin Mück-Häusl, Marvin M. Festag, Theresa Asen, Ulrike Protzer   +5 more
openalex   +1 more source

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

Advanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu, Zhe Wang, Diwei Zheng, Yongfang Zheng, Zhiwu Jiang, Jiang Lv, Yueqin Zhu, Heng Jia, Ziyuan Duan, Tingjie Yuan, Qiting Wu, Youguo Long, Shouheng Lin, Yao Yao, Georgia Carson, Jean P. Thiery, Kwan Man, Peng Li   +17 more
wiley   +1 more source

A hepatitis C virus (HCV) fertőzés pathogenesise: a genetikai és az immunológiai tényezők, valamint az oxidativ stress szerepe és a kórokozó virus sajátosságai, különös tekintettel a HCV-okozta betegségekben és a tünetmentes virushordozó állapotban = Pathogenesis of hepatitis C virus (HCV) infection: the role of the genetic and immunological factors, the oxidative stress and the viral features in the HCV-related diseases and in the symptomfree virus carriers [PDF]

, 2009
Genetikai, immunológiai és környezeti tényezők potenciális szerepe krónikus hepatitis C virus (HCV) infekcióban: összehasonlitó vizsgálatok aktiv HCV hepatitises betegekben és tünetmentes "egészséges" virushordozókban. 1.
Berki, Timea, Hunyady, Béla, Kalabay, László, Nagy, Zsuzsanna, Pár, Alajos, Pár, Gabriella   +5 more
core  

Hepatitis E Virus ORF1 Polyprotein Harbors a Pocket‐Like Cavity That Is Vital for Virus Replication and Represents a Novel Antiviral Target

Advanced Science, EarlyView.
Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding, Dou Zeng, Dan Liu, Yingying Bian, Bin Li, Zheng Li, Qiudi Li, Shiquan Liang, Yunlong Si, Qili Yao, Yibo Ding, Jiahui Zhu, Xiangyang Li, Kuiyang Zheng, Hongbo Guo, Wenshi Wang   +15 more
wiley   +1 more source

Inhibiting Liver‐Derived C3 Protein Rescues Anesthesia/Surgery‐Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis

Advanced Science, EarlyView.
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu, Peilin Cong, Zhouxiang Li, Yuxin Zhang, Huanghui Wu, Qian Zhang, Yawei Li, Li Tian, Qingyuan Miao, Yinggang Zheng, Hui Zhang, Qian Chen, Enduo Feng, Xinyang Li, Zheping Chen, Dong‐Xin Wang, Xinwei Huang, Lize Xiong   +17 more
wiley   +1 more source

Hepatitis B virus compartmentalization and single-cell differentiation in hepatocellular carcinoma [PDF]

, 2021
Frank Juehling, Antonio Saviano, Clara Ponsolles, Laura Heydmann, Émilie Crouchet, Sarah Durand, Houssein El Saghire, Emanuele Felli, Véronique Lindner, Patrick Pessaux, Nathalie Pochet, Catherine Schuster, Éloi R. Verrier, Thomas F. Baumert   +13 more
openalex   +1 more source