Results 81 to 90 of about 193,736 (306)

Estimation of hepatitis E virus transmission among pigs due to contact-exposure

open access: yes, 2008
Locally acquired hepatitis E in humans from industrialized countries has been repeatedly suggested to originate from pigs. Pigs may serve as a reservoir of hepatitis E virus (HEV) for humans when a typical infected pig causes on average more than one ...
Saskia A. Rutjes   +23 more
core   +1 more source

Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection. [PDF]

open access: yes, 2011
BACKGROUND: Dengue virus is transmitted by mosquitoes and has four serotypes. Cross-protection to other serotypes lasting for a few months is observed following infection with one serotype.
Low, Jenny G.   +62 more
core   +1 more source

Are International Units of Anti-HBs Antibodies Always Indicative of Hepatitis B Virus Neutralizing Activity?

open access: yes, 2023
Objective: Anti-HBs antibodies are elicited upon hepatitis B vaccination, and concentrations above 10 mIU/mL are considered protective. Our aim was to assess the relationship between IU/mL of anti-HBs and neutralization activity. Methods: Immunoglobulins
Nathan Szerman   +15 more
core   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei   +11 more
wiley   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu   +11 more
wiley   +1 more source

Hepatitis B virus seromarkers as an unmet need for screening among patients in North India

open access: yesJournal of Family Medicine and Primary Care
Background: Chronic Hepatitis B is a global public health concern with significant morbidity and mortality. Identification of serological markers is essential for diagnosis, monitoring, and treatment planning. Objectives: To determine the distribution of
Sana Irfan, Pankaj Kumar, Kumari Seema
doaj   +1 more source

High prevalence of anti-HCV antibodies in two metropolitan emergency departments in Germany : a prospective screening analysis of 28,809 patients

open access: yes, 2012
Background and Aims: The prevalence of hepatitis C virus (HCV) antibodies in Germany has been estimated to be in the range of 0.4–0.63%. Screening for HCV is recommended in patients with elevated ALT levels or significant risk factors for HCV ...
Hintereder, Gudrun   +31 more
core   +1 more source

Data for: Understanding the Influence of Maternal Hepatitis B E Antibodies Transfer in Neonates: Analyzing Antibodies, myeloid-derived suppressor cells (MDSCs), and their Interplay in the Context of Chronic Hepatitis B and Chronic Hepatitis B-Delta Coi...

open access: yes, 2023
This data set consists of 87 distinct samples extracted from the case report, along with three existing tests on the mother of the individual mentioned in the report.
Oprea, C (via Mendeley Data)
core   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

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