Results 101 to 110 of about 54,525 (278)
Adaptive immunity in cancer immunology and therapeutics. [PDF]
, 2014 Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution,
Lockley, M, Spurrell, EL
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Protein glycosylation as a diagnostic and prognostic marker of chronic inflammatory gastrointestinal and liver diseases [PDF]
, 2020 Glycans are sequences of carbohydrates that are added to proteins or lipids to modulate their structure and function. Glycans modify proteins required for regulation of immune cells, and alterations have been associated with inflammatory conditions.
Callewaert, Nico +6 more
core +1 more source
Advances in Double‐Stranded DNA Targeting Technologies
Exploration, EarlyView.Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen +8 more
wiley +1 more source
Cell surface-specific N-glycan profiling in breast cancer [PDF]
, 2013 Aberrant changes in specific glycans have been shown to be associated with immunosurveillance, tumorigenesis, tumor progression and metastasis. In this study, the N-glycan profiling of membrane proteins from human breast cancer cell lines and tissues was
Chen, Cuiying +8 more
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Immunogenicity evaluation of a DNA vaccine expressing the hepatitis C virus non-structural protein 2 gene in C57BL/6 Mice [PDF]
, 2013 Backgrounds: Most of the hepatitis C virus (HCV) infections elicit poor immune responses and 75% to 85% of cases become chronic; therefore, the development of an effective vaccine against HCV is of paramount importance.
Behnampour, N. +5 more
core +2 more sources
Characteristics of Hepatitis B Infection in a Sample of Omani Patients
Sultan Qaboos University Medical Journal, 2013 Objectives: This study aimed to describe the demographic and virological characteristics of chronic hepatitis B virus (HBV) infection in a sample of Omani patients, and indirectly assess the efficacy of hepatitis B vaccination programmes and catch-up ...
Khalid Al-Naamani +2 more
doaj
Cure of chronic viral infection and virus-induced type 1 diabetes by neutralizing antibodies [PDF]
, 2009 The use of neutralizing antibodies is one of the most successful methods to interfere with receptor–ligand interactions in vivo. In particular blockade of soluble inflammatory mediators or their corresponding cellular receptors was proven an effective ...
Christen, Urs +2 more
core
Assembly and Antigenicity of Hepatitis B Virus Core Particles
Intervirology, 1995 Recent studies in Xenopus oocytes and other systems have led to an understanding of the HBV capsid, or core particle, assembly process. Nascent HBV core polypeptides rapidly dimerize. Accumulation of free dimers to a signature concentration (approximately 0.8 microM) then triggers a highly cooperative capsid assembly reaction.
M, Seifer, D N, Standring
openaire +2 more sources
iNew Medicine, EarlyView.ABSTRACT Hepatocellular carcinoma (HCC) represents a significant global health issue, with the PD‐1/PD‐L1 axis serving a pivotal target for immunotherapy in this malignancy. However, a comprehensive bibliometric analysis of PD‐1/PD‐L1 research in HCC is lacking.
Xingyu Zhu +4 more
wiley +1 more source
Fucosyltransferase 1 and 2 play pivotal roles in breast cancer cells. [PDF]
, 2019 FUT1 and FUT2 encode alpha 1, 2-fucosyltransferases which catalyze the addition of alpha 1, 2-linked fucose to glycans. Glycan products of FUT1 and FUT2, such as Globo H and Lewis Y, are highly expressed on malignant tissues, including breast cancer ...
Chang, Nai-Chuan +9 more
core +2 more sources