Results 221 to 230 of about 14,427,656 (303)

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang, Yin Zhu, Fang Xu, Yongjing Liu, Yuan Li, Ling Yuan, Liqin Wei, Bo Huang, Yan Chen, Pei Huang, Zuochen Du   +10 more
wiley   +1 more source

A PEGylated nanobody against HBsAg exhibits pleiotropic antiviral efficacy in hepatitis B models. [PDF]

J Nanobiotechnology
Yang Q, Liu W, Huang M, Lin M, Hu J, Wei J, Yang Q, Wang S, Wang D, Huang A, Cai X.   +10 more
europepmc   +1 more source

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

MedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu, Yuqin Jin, Baochao Li, Jie Deng, Yiwen Zhou, Jinglun Zhang, Huang Li   +6 more
wiley   +1 more source

Immune correlates of outcomes after nucleos(t)ide analogue withdrawal in chronic hepatitis B: direct evidence, mechanistic context, and candidate biomarkers. [PDF]

Front Immunol
Xu Z, Liu Y, Cheng L, Xu J.
europepmc   +1 more source

Restricted TCR Diversity and Expansion of CD177+CD8+ and TLR4+CD4+T Cell Subsets in Septic Shock‐Associated Immunosuppression: A Single‐Cell Multi‐Omics Study

MedComm, Volume 7, Issue 9, September 2026.
Our study enrolled 10 septic shock patients with immunosuppression and 10 healthy controls and sorted CD8+ and CD4+ T cells for transcriptome sequencing. Disease‐specific cell types, key transcripts, and TCR features were identified using integrated analysis.
Yawen Xie, Xunyao Wu, Guoyu Zhao, Xianli Lei, Jiahui Zhang, Na Cui, Bin Du   +6 more
wiley   +1 more source

Hepatitis B and D burden in Uzbekistan: comprehensive analysis of seroprevalence and risk correlates from a countrywide study. [PDF]

Infect Dis Poverty
Musabaev EI, Khodjaeva ME, Khikmatullaeva AS, Ibadullaeva NS, Shodieva FSK, Khudaykulova GK, Tadjieva NU, Amonov SB, Mirzaev UK.   +8 more
europepmc   +1 more source

Abscopal Effect in Radiation Therapy: The Immune Mechanisms and Clinical Advances

MedComm, Volume 7, Issue 9, September 2026.
The schematic outlines the key events of the abscopal effect. (Ignition) Local radiotherapy (RT) induces the release of immunogenic signals from the tumor, leading to dendritic cell (DC) activation. (Orchestration) In the tumor‐draining lymph node (TDLN), DCs prime naive T cells into cytotoxic T lymphocytes (CTLs), a process modulated by regulatory T ...
Yihong Dong, Moran Chen, Xupeng Hou, Xiaoya Tang, Xiaoli Yu, Jing Liu   +5 more
wiley   +1 more source

Development of a vaccine delivery system using hepatitis B core antigen based VLPs to deliver mycobacterial antigens

BMC Infectious Diseases, 2012
Dhanasooraj Dhananjayan, Kumar R, Mundayoor Sathish   +2 more
doaj   +1 more source

The clinical significance and optimization strategies of HBeAg seroclearance in chronic hepatitis B treatment. [PDF]

Front Cell Infect Microbiol
Zhang Y, Gao Y, Li X, Zhang Z, Wang S, Gao Z, Xie Y, Li M.   +7 more
europepmc   +1 more source