Results 91 to 100 of about 71,240 (317)

Anti-Hepatitis B Virus Activity of Chickweed [<em>Stellaria media</em> (L.) Vill.] Extracts in HepG2.2.15 Cells

open access: yesMolecules, 2012
<em>Stellaria media </em>(Linn.) Villars is a traditional Chinese medicine that has been used for over 200 years, mainly for the treatment of dermatitis and other skin diseases. It has also been used as an anti-viral agent.
Donghao Xie   +6 more
doaj   +1 more source

Quantitative hepatitis B e antigen: a better predictor of hepatitis B virus DNA than quantitative hepatitis B surface antigen

open access: yes, 2018
Background: Hepatitis B surface antigen is usually secreted by infected hepatocytes in the form of subviral particles rather than infectious virions, while the hepatitis B e antigen originates from the core gene and is modified and secreted by ...
Sekawi, Zamberi   +15 more
core   +1 more source

Host iron redistribution as a risk factor for incident tuberculosis in HIV infection: an 11-year retrospective cohort study. [PDF]

open access: yes, 2013
BACKGROUND: Identifying people at higher risk of developing tuberculosis with human immunodeficiency virus (HIV) infection may improve clinical management of co-infections.
Jaye Assan   +29 more
core   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

open access: yesAdvanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu   +6 more
wiley   +1 more source

Characteristics of Hepatitis B Infection in a Sample of Omani Patients

open access: yesSultan Qaboos University Medical Journal, 2013
Objectives: This study aimed to describe the demographic and virological characteristics of chronic hepatitis B virus (HBV) infection in a sample of Omani patients, and indirectly assess the efficacy of hepatitis B vaccination programmes and catch-up ...
Khalid Al-Naamani   +2 more
doaj  

Surgical Outcomes and Recurrence Management in Borderline Resectable Hepatocellular Carcinoma: Implications for Multidisciplinary Strategies

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Multivariate analysis identified that up‐to‐7 out (p < 0.001), lymph node metastasis (p < 0.001), and non‐anatomical resection (p = 0.02) were independent predictors of cancer recurrence, while older age (p = 0.01), Child‐Pugh B (p < 0.001), up‐to‐7 out (p = 0.01), macrovascular invasion (p = 0.01), and lymph node metastasis (p < 0.001) were ...
Koichiro Haruki   +9 more
wiley   +1 more source

Effects of mRNA secondary structure on the expression of HEV ORF2 proteins in Escherichia coli

open access: yesMicrobial Cell Factories, 2017
Background Viral protein expression in Escherichia coli (E. coli) is a powerful tool for structural/functional studies as well as for vaccine and diagnostics development.
Nouredine Behloul   +5 more
doaj   +1 more source

Cumulative Antigen Suppression Reduces Clonal Plasma Cell Evolution in Gaucher Disease

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Chronic antigenic stimulation is implicated in the pathogenesis of monoclonal gammopathy and multiple myeloma, yet longitudinal human evidence linking sustained antigen exposure to modifiable clonal plasma cell evolution remains limited. Gaucher disease (GD), caused by biallelic GBA1 pathogenic variants, is characterized by accumulation of ...
Noor Ul Ain   +10 more
wiley   +1 more source

IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic Hepatitis C virus infection in a European cohort: A cross-sectional study

open access: yes, 2011
Background To date, drug response genes have not proved as useful in clinical practice as was anticipated at the start of the genomic era. An exception is in the treatment of chronic hepatitis C virus (HCV) genotype 1 infection with pegylated interferon-
Hellard, M   +159 more
core   +1 more source

Hepatitis C virus infection epidemiology among people who inject drugs in Europe: a systematic review of data for scaling up treatment and prevention. [PDF]

open access: yes, 2014
BACKGROUND: People who inject drugs (PWID) are a key population affected by hepatitis C virus (HCV). Treatment options are improving and may enhance prevention; however access for PWID may be poor.
Mcdonald, B   +210 more
core   +1 more source

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