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Serum Hepatitis B Surface Antigen Levels Predict Surface Antigen Loss in Hepatitis B e Antigen Seroconverters

Gastroenterology, 2011
Loss of hepatitis B surface antigen (HBsAg) usually indicates that hepatitis B virus (HBV) infection has been cured. However, little is known about factors predicting HBsAg loss in patients who spontaneously clear hepatitis B e antigen (HBeAg).We studied 390 Taiwanese HBeAg-positive patients with chronic hepatitis who had spontaneously cleared HBeAg ...
Tai-Chung, Tseng   +7 more
openaire   +2 more sources

Extended lamivudine consolidation therapy in hepatitis B e antigen-positive chronic hepatitis B patients improves sustained hepatitis B e antigen seroconversion

Scandinavian Journal of Gastroenterology, 2009
Longer lamivudine (LAM) consolidation therapy after hepatitis B e antigen (HBeAg) seroconversion has been demonstrated to reduce the cumulative relapse rate. However, the optimal interval of LAM consolidation therapy remains controversial. We evaluated the post-treatment durability of LAM-induced HBeAg seroconversion and the length of LAM consolidation
Yuan-Hung, Kuo   +7 more
openaire   +2 more sources

Hepatitis B e antigen positive mother hepatitis B e antigen long persistence in her non‐infected baby

Acta Paediatrica, 2006
AbstractWe report the case of a baby born to a hepatitis B virus (HBV) carrier mother. This infant had a hepatitis B e antigen (HBeAg) in the serum until 6 months of age. Serial sera samples were analysed for HBV markers. No breakthrough of HBV infection was detected.
D, Selton   +3 more
openaire   +2 more sources

Hepatitis B e Antigen — The Dangerous Endgame of Hepatitis B

New England Journal of Medicine, 2002
The external pernicious influences of wind and dampness cause liver Qi to stagnate, and excess damp heat in liver and weakness of spleen Qi result.
T. Jake Liang, Marc Ghany
openaire   +1 more source

Hepatitis B e Antigen and Antibody Measured by Radioimmunoassay in Acute Hepatitis B Surface Antigen-Positive Hepatitis

Journal of Infectious Diseases, 1980
The presence of the hepatitis B e antigen (HBeAg) and antibody to HBeAg (anti-HBe) was studied by a solid-phase radioimmunoassay in 70 patients with acute hepatitis positive for hepatitis B surface antigen. HBeAg was found in 15 of 16 patients studied within two weeks after onset of symptoms. In total, 45 patients were found positive for HBeAg.
J, Aldershvile   +5 more
openaire   +2 more sources

Factors affecting clearance of hepatitis B e antigen in hepatitis B surface antigen carrier children

The Journal of Pediatrics, 1989
To understand the natural history of chronic hepatitis B virus infection in children, we studied factors affecting the clearance of hepatitis B e antigen (HBeAg). One hundred sixty-nine apparently healthy children whose sera were positive for HBeAg and hepatitis B surface antigen (HBsAg) and who were recruited by screening were followed prospectively ...
CHANG, MEI-HWEI   +7 more
openaire   +2 more sources

Seroconversion from Hepatitis B e Antigen in Chronic Type B Hepatitis

Annals of Internal Medicine, 1981
Excerpt To the editor: I read with great interest the paper by Hoofnagle and associates (1). Information on the natural history of type B chronic hepatitis is welcomed by anyone treating patients w...
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Hepatitis B e Antigen (HBeAg)

1985
A third antigenic specificity associated with HBV infection, designated as e antigen or HBeAg, was found in the sera of some individuals with acute or chronic hepatitis as detected by immunodiffusion (51, 52, 459). The screening of HBsAg positive sera from hemodialysis patients for this antigen revealed a close correlation between the presence of e ...
openaire   +1 more source

Immune correlates of hepatitis B surface antigen spontaneous seroconversion in hepatitis B e antigen negative chronic hepatitis B patients

Liver International, 2017
AbstractBackgroundHepatitis B surface antigen (HBsAg) seroconversion in HBeAg −ve chronic hepatitis B (CHB) infection is rare, possibly due to poor antigen processing and impaired humoral response. We investigated the role of dendritic cells (DCs), T follicular helper (TFH) cells and plasma B cells in seroconversion.MethodsHBeAg −ve (n=135) CHB ...
Ashish Kumar Vyas   +3 more
openaire   +2 more sources

Quantitative Hepatitis B e Antigen: A Better Predictor of Hepatitis B Virus DNA than Quantitative Hepatitis B Surface Antigen

Clinical Laboratory, 2018
Hepatitis B surface antigen is usually secreted by infected hepatocytes in the form of subviral particles rather than infectious virions, while the hepatitis B e antigen originates from the core gene and is modified and secreted by hepatocytes into the circulation and functions as a marker of active viral replication.
Hudu, Shuaibu A.   +7 more
openaire   +2 more sources

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