Results 171 to 180 of about 40,026,108 (306)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

The GOLDEN Model Effectively Predicts Hepatitis B Surface Antigen Seroclearance in Untreated Patients in Real World Clinical Practice. [PDF]

J Med Virol
Hao K, Zhao S, Liao X, Fan R, Naoumov NV, Yu Y, Hou J.   +6 more
europepmc   +1 more source

Pruritic Perifollicular Umbilicated Papules in an Elderly Diabetic Patient

JEADV Clinical Practice, EarlyView.
Ojaswini Gadbail, Asharbh Raman, Kalyan Dalave, Priya Dev   +3 more
wiley   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Enterovirus infections in children

Pediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen, Lingyun Guo, Xiaobo Lei, Linqing Zhao, Mingyan Hei, Jun Shen, Ju Yin, Fei Li, Jikui Deng, Gang Liu, Yong Zhang, Zhengde Xie   +11 more
wiley   +1 more source

Analytical performance evaluation of MAGLUMI HBeAg and anti-HBe chemiluminescence immunoassays and comparison with the Abbott assays. [PDF]

Front Cell Infect Microbiol
Zeng J, Zhao X, Wang W, Wang J, Li X, Zheng K, Zhang H, Yin J, Fang Z.   +8 more
europepmc   +1 more source

Hepatitis B : are you at risk? [Swahili]

Hepatitis B : are you at risk? [Swahili]Kama wewe au wazazi wako walizaliwa Afrika, ongea na daktari wako kuhusu kupimwa Hepatitisi BThese sheets have the English translation on the back.cdc/gov/knowhepatitisBFactSheet-HepBAreYouAtRisk_swa-eng ...

core  

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Immunogenicity of a Candidate Hepatitis C Vaccine Based on Non-Structural DNA-Protein Sequences and a Novel Complex Adjuvant. [PDF]

Vaccines (Basel)
Masalova OV, Lesnova EI, Kozlov VV, Valuev-Elliston VT, Permyakova KY, Fedorova NE, Nikolaeva TN, Pronin AV, Ivanov AV, Kushch AA.   +9 more
europepmc   +1 more source

Hepatitis B : are you at risk? [Somali]

Hepatitis B : are you at risk? [Somali]Haddii adiga ama waalidkaagu ay ku dhasheen Soomaaliya, kala hadal dhakhtarkaaga waxa ku saabsan in lagaa baaro Cagaarshowga B.These sheets have the English translation on the back.cdc/gov/knowhepatitisBFactSheet ...

core