Results 191 to 200 of about 119,184 (308)

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Tracking Canada's 2015 vaccine research and development priorities: Where are we a decade later? [PDF]

Can Commun Dis Rep
Moqueet N, Lago K, Cortés-Kaplan S, Birdi H, Desai S, Gauhar A, Warshawsky B, Tunis M, Wilkinson K.   +8 more
europepmc   +1 more source

ASSOCIATION OF HLA COMPATIBILITY AND DECREASED LIVER-TRANSPLANT SURVIVAL [PDF]

, 1988
BRYAN, C, DUQUESNOY, RJ, FUNG, JJ, GORDON, RD, KLINTMALM, G, MARKUS, BH, STARZL, TE, VANEK, M, VANTHIEL, D   +8 more
core  

Perspectives on Pertussis Prevention

Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Oncolytic Vaccinia Virus‐HSP70‐shRNA Amplifies Viral Replication, ROS/Autophagy, and Immunity to Fight Colorectal Cancer

Cancer Science, EarlyView.
OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan, Ruikang Liu, Fangying Shao, Zheqi Cai, Yingfei Fang, Kan Chen, Yanrong Zhou, Ting Ye, Gongchu Li   +8 more
wiley   +1 more source

Plant-based production of virus-like particles from hepatitis C virus. [PDF]

Planta
López-Castillo LM, Gonzalez-Castro R, Sánchez-Segura L, Aguilar-Barragán BA, Lim MAG.   +4 more
europepmc   +1 more source

Single Cell Multi‐Omics Revealing the Important Role of MR1 Mediated MAIT Cells in Maintaining Rejection for Liver Transplantation

Cell Proliferation, EarlyView.
This multi‐omics study reveals the significant role of MAIT cells in liver transplant rejection. MAIT cells drive rejection in liver transplantation via the MR1 axis. Their absence reshapes T cell responses and clonal expansion, attenuating allograft injury.
Hailun Cai, Xinqiang Li, Xin Zhou, Xueteng Wang, Zhuoyu Jia, Ruidong Ding, Yurong Luo, Ye Wang, Shipeng Li, Wenxing Sun, Dongxing Wu, Dahong Teng, Kai Zhao, Guanghui Pei, Jinzhen Cai, Bin Wu   +15 more
wiley   +1 more source

Kaempferol inhibits hepatitis B virus replication <i>via</i> ERK/FOXO1 pathway-mediated suppression of the viral core promoter. [PDF]

Front Cell Infect Microbiol
Deng W, Luo Z, Yu H, Chen F, Ding J, Dai C, Zhang X, Qin B, Dou J, Guo M.   +9 more
europepmc   +1 more source

Targeting Egfr‐Mediated Cell Proliferation and Lipid Metabolism Separation Effectively Accelerate Liver Regeneration

Cell Proliferation, EarlyView.
AREG coordinates cell proliferation and lipid metabolism reprogramming during liver regeneration and targeting lipid metabolism can promote liver regeneration. ABSTRACT Hepatocyte proliferation restores liver mass after partial hepatectomy (PHx), but the metabolic cost of this process remains unclear.
Yuelei Hu, Shifei Song, Ruilin Wang, Ni An, Jinmei Diao, Yuguo Chen, Juan Liu, Guoyue Lv   +7 more
wiley   +1 more source

Investigation of the sero-epidemiology of vaccine preventable diseases and common viral infections in French populations. [PDF]

Commun Med (Lond)
Bloch E, Baudemont G, Donnadieu F, Garcia L, Pelleau S, SeroPed Study Consortium, Milieu Intérieur Consortium, Quintana-Murci L, Duffy D, Fontanet A, White M.   +10 more
europepmc   +1 more source