Results 31 to 40 of about 69,025 (166)

Predictive value of HBeAg titer dynamics for HBsAg clearance in pediatric chronic hepatitis B

Frontiers in Pediatrics
IntroductionAchieving functional cure of chronic hepatitis B (CHB), characterized by the loss of HBV DNA and HBsAg, remains challenging in adults but demonstrates higher success rates in children.
Sukjin Hong, Jun Hyun Hwang, Keumoung Kim, Younghae Do, Naeun Kwak, Hyo Rim Suh, Sujin Choi, Ben Kang, Byung-Ho Choe   +8 more
doaj   +1 more source

Seroprevalence for Hepatitis E and Other Viral Hepatitides among Diverse Populations, Malawi

Emerging Infectious Diseases, 2015
Data on prevalence of hepatitis E virus (HEV) in Malawi is limited. We tested blood samples from HIV-uninfected and -infected populations of women and men enrolled in research studies in Malawi during 1989–2008 to determine the seroprevalence of HEV ...
Taha E. Taha, Laura K. Rusie, Alain Labrique, Mulinda Nyirenda, Dean Soko, Melvin Kamanga, Johnstone Kumwenda, Homayoon Farazadegan, Kenrad Nelson, Newton Kumwenda   +9 more
doaj   +1 more source

High Hepatitis B Surface Antigen Levels Predict Insignificant Fibrosis in Hepatitis B e Antigen Positive Chronic Hepatitis B

PLoS ONE, 2012
There is no data on the relationship between hepatitis B surface antigen (HBsAg) levels and liver fibrosis in hepatitis B e antigen (HBeAg)-positive patients with chronic hepatitis B (CHB).Serum HBsAg and HBV DNA levels in HBeAg-positive CHB patients with liver biopsies were analyzed.
Lai, CL, Yuen, JCH, Hung, IFN, Yuen, MF, Seto, WK, Wong, DKH, Fung, J, Ip, PPC   +7 more
openaire   +6 more sources

Hepatitis associated with hepatitis B virus in broilers

Journal of Integrative Agriculture, 2016
Infection by hepatitis B virus (HBV) results in acute and chronic liver damages in humans. Liver products of broilers as a primary food consumed in our daily life have a close connection with public health. The prevalence of the virus in livers and serum
Yue ZHAO, Jing-jing MAO, Rui-ping SHE, Feng-jiao HU, Majid H Soomro, Rui-ping LIANG, Yi-fei YANG, Fang DU, Tong-tong WANG, Zhao-jie GUO, Min-heng CHENG   +10 more
doaj   +1 more source

Treatment of chronic hepatitis B naïve patients with a therapeutic vaccine containing HBs and HBc antigens (a randomized, open and treatment controlled phase III clinical trial). [PDF]

PLoS ONE, 2018
CONTEXT:Current drugs for chronic hepatitis B therapy have a poor efficacy in terms of post-treatment sustained viral suppression and generate important side effects during and after therapy.
Mamun Al Mahtab, Sheikh Mohammad Fazle Akbar, Julio Cesar Aguilar, Gerardo Guillen, Euduaro Penton, Angela Tuero, Osamu Yoshida, Yoichi Hiasa, Morikazu Onji   +8 more
doaj   +1 more source

T cell--associated immunoregulation and antiviral effect of oxymatrine in hydrodynamic injection HBV mouse model

Acta Pharmaceutica Sinica B, 2017
Although oxymatrine (OMT) has been shown to directly inhibit the replication of hepatitis B virus (HBV) in vitro, limited research has been done with this drug in vivo.
Xiuxiu Sang, Ruilin Wang, Yanzhong Han, Cong'en Zhang, Honghui Shen, Zhirui Yang, Yin Xiong, Huimin Liu, Shijing Liu, Ruisheng Li, Ruichuang Yang, Jiabo Wang, Xuejun Wang, Zhaofang Bai, Xiaohe Xiao   +14 more
doaj   +1 more source

Treatment with the Immunomodulator AIC649 in Combination with Entecavir Produces Antiviral Efficacy in the Woodchuck Model of Chronic Hepatitis B

Viruses, 2021
As current interventions for chronic hepatitis B (CHB) rarely induce cure, more effective drugs are needed. Short-term treatment of woodchucks with the novel immunomodulator AIC649, a parapoxvirus-based stimulator of toll-like receptor 9 dependent and ...
Kyle E. Korolowicz, Manasa Suresh, Bin Li, Xu Huang, Changsuek Yon, Xuebing Leng, Bhaskar V. Kallakury, Robin D. Tucker, Stephan Menne   +8 more
doaj   +1 more source

Risk of hepatocellular carcinoma in untreated patients with chronic hepatitis B: Independent of HBeAg status? [PDF]

Clinical and Molecular Hepatology, 2021
Ho Soo Chun, Minjong Lee
doaj   +1 more source

Hepatitis B seroconversion revisited: new insights into the natural history of acute hepatitis B virus (HBV) infection from quantitative and highly sensitive assays and novel biomarkers

Virology Journal, 2021
Background Hepatitis B virus (HBV) serum markers during typical acute self-limited infection are usually depicted as a composite of traditional HBV markers.
Mary C. Kuhns, Vera Holzmayer, Anne L. McNamara, Mark Anderson, Gavin A. Cloherty   +4 more
doaj   +1 more source

Virus-like Particle Vaccines and Platforms for Vaccine Development

Viruses, 2023
Virus-like particles (VLPs) have gained a lot of interest within the past two decades. The use of VLP-based vaccines to protect against three infectious agents—hepatitis B virus, human papillomavirus, and hepatitis E virus—has been approved; they are ...
Milad Kheirvari, Hong Liu, Ebenezer Tumban   +2 more
doaj   +1 more source