Results 11 to 20 of about 470,387 (242)

A Multivalent mRNA Therapeutic Vaccine Exhibits Breakthroughs in Immune Tolerance and Virological Suppression of HBV by Stably Presenting the Pre-S Antigen on the Cell Membrane [PDF]

Pharmaceutics
Background/Objectives: In chronic hepatitis B infection (CHB), the hepatitis B surface antigen (HBsAg) continuously exhausts the hepatitis B surface antibody (HBsAb), which leads to the formation of immune tolerance.
Shang Liu, Jie Wang, Yunxuan Li, Muhan Wang, Pei Du, Zhijie Zhang, Wenguo Li, Rongchen Sun, Mingtao Fan, Meijia Yang, Hongping Yin   +10 more
doaj   +2 more sources

Persistence of antibody to hepatitis B surface antigen [PDF]

Journal of Clinical Microbiology, 1976
Sera from military personnel found to have antibodies to hepatitis B surface antigen (anti-HBS) in an epidemiological study of a hepatitis B outbreak were tested for persistence of that antibody 1 year later. Initially, 64% of the anti-HBS-positive sera reacted in passive hemagglutination tests with erythrocytes coated with hepatitis B surface antigen ...
Gilbert R. Irwin, Alfred M. Allen, Herbert E. Segal, Milton Willhight, HUBERT G. CANNON, Franklin H. Top   +5 more
openalex   +4 more sources

Correlation between serum quantitative HBsAg and HBV DNA levels in chronic hepatitis B patients [PDF]

Vojnosanitetski Pregled, 2023
Background/Aim. Quantitative hepatitis B virus (HBV) surface antigen (qHBsAg) has become increasingly wide-spread in the last few years in both diagnostic and therapeutic protocols for HBV infection.
Pete Maria, Ružić Maja, Kovačević Nadica, Petrić Vedrana, Milošević Ivana, Preveden Tomislav   +5 more
doaj   +1 more source

Prevalence of hepatitis B in dental patients

Journal of Indian Academy of Oral Medicine and Radiology, 2023
Background: Hepatitis B virus (HBV) infection is one of the leading causes of death worldwide. The most important marker for HBV infection is HBsAg. In case of diagnosis of infectious disease, discordant results may have serious consequences among the ...
Ashmita Kaur R. Chawla, Tanvi R Dosi, Tushar Phulambrikar   +2 more
doaj   +1 more source

Proteins of hepatitis B surface antigen [PDF]

Journal of Virology, 1977
Purified 22-nm forms of hepatitis B surface antigen (Hbsag) representing the three major antigenic subtypes (adw, ayw, and adr) were analyzed for their constituent polypeptides by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. No consistent difference in either the number or relative distributions of the polypeptides was observed for the ...
J. L. Gerin, J. W. K. Shih
openaire   +3 more sources

Nuclear Expression of Hepatitis B Virus X Protein Is Associated with Recurrence of Early-Stage Hepatocellular Carcinomas: Role of Viral Protein in Tumor Recurrence [PDF]

Journal of Pathology and Translational Medicine, 2016
Background: Hepatitis B virus (HBV) plays well-known roles in tumorigenesis of hepatocellular carcinoma (HCC) in infected patients. However, HBV-associated protein status in tumor tissues and the relevance to tumor behavior has not been reported.
Jing Jin, Hae Yoen Jung, Kyu Ho Lee, Nam-Joon Yi, Kyung-Suk Suh, Ja-June Jang, Kyoung-Bun Lee   +6 more
doaj   +1 more source

Safety considerations for withdrawal of nucleos(t)ide analogues in patients with chronic hepatitis B: First, do no harm [PDF]

Clinical and Molecular Hepatology, 2023
Nucleos(t)ide analogues (NA) are widely used to treat hepatitis B virus (HBV) infection, but they cannot eradicate the virus and treatment duration can be lifelong if the endpoint is set at seroclearance of the hepatitis B surface antigen (HBsAg).
Yao-Chun Hsu, Cheng-Hao Tseng, Jia-Horng Kao   +2 more
doaj   +1 more source

Persistence of intrahepatic hepatitis B virus DNA integration in patients developing hepatocellular carcinoma after hepatitis B surface antigen seroclearance [PDF]

Clinical and Molecular Hepatology, 2021
Background/Aims The role of hepatitis B virus (HBV) integration into the host genome in hepatocarcinogenesis following hepatitis B surface antigen (HBsAg) seroclearance remains unknown.
Jeong Won Jang, Jin Seoub Kim, Hye Seon Kim, Kwon Yong Tak, Heechul Nam, Pil Soo Sung, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Lewis R. Roberts   +9 more
doaj   +1 more source

Changes in the Hepatitis B Surface Antigen Level According to the HBeAg Status and Drug Used in Long-term Nucleos(t)ide Analog-treated Chronic Hepatitis B Patients

The Korean Journal of Gastroenterology, 2021
Background/Aims: The HBsAg levels have been used to monitor the chronic hepatitis B (CHB) treatment response to antiviral therapy. On the other hand, it is unclear if the HBsAg quantification levels at each treatment point differ according to the HBeAg ...
Jong Hwa Na, Jeong Han Kim, Won Hyeok Choe, So Young Kwon, Byung Chul Yoo   +4 more
doaj   +1 more source

Humoral Immune Memory to Hepatitis B Vaccine after Primary Vaccination of Children and Adolescents in Assiut, Egypt

Oman Medical Journal, 2020
Objectives: We sought to assess the prevalence of hepatitis B virus (HBV) seroprotection among vaccinated children in the Assiut governorate, Egypt, and assess a booster dose immune memory response among non-seroprotected children.
Iman I. Salama, Samia M. Sami, Safaa M. Elserougy, Hanaa M. Emam, Somaia I. Salama, Hazem A. Elhariri, Samia A. Hemeda, Amal I. Hassanain, Aida M. Abdel Mohsen, Walaa A. Fouad, Lobna A. El Etreby, Zeinab N. Said   +11 more
doaj   +1 more source