Results 191 to 200 of about 101,616 (361)

When more isn't better: the surprising superiority of glycoprotein-only Marburg vaccines. [PDF]

J Clin Invest
Penaloza-MacMaster P.
europepmc   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

Recombinant Yeast-Based Vaccines: Importance and Applications. [PDF]

Infect Dis Rep
Kumar R.
europepmc   +1 more source

Efficacy and Safety of Tenofovir Alafenamide (TAF) and Tenofovir Disoproxil Fumarate (TDF) Followed by TAF in Chronic Hepatitis B Patients of East Asian Ethnicity Following 5 Years of Treatment

Alimentary Pharmacology &Therapeutics, EarlyView.
In East Asian patients with chronic hepatitis B, rates of virologic suppression through 5 years were high in those treated continuously with tenofovir alafenamide (TAF) and in those switched from tenofovir disoproxil fumarate (TDF) to TAF. Improved renal and bone safety was observed in patients switching from TDF to TAF.
Grace Lai‐Hung Wong, Edward Gane, Calvin Q. Pan, Scott Fung, Mang M. Ma, Namiki Izumi, Shalimar, Seng Gee Lim, Wan‐Long Chuang, Rajiv Mehta, Young‐Suk Lim, Leland J. Yee, John F. Flaherty, Frida Abramov, Hongyuan Wang, Maria Buti   +15 more
wiley   +1 more source

Universal screening for viral hepatitis in all inpatients of a university internal medicine department. [PDF]

Ann Gastroenterol
Protopapas AA, Protopapa N, Kyritsi V, Filippidis A, Savopoulos C, Protopapas AN.   +5 more
europepmc   +1 more source

Long‐Term Follow‐Up of Patients in a Prospective Study of NA Discontinuation Identifies Different Patterns of HBsAg Loss

Alimentary Pharmacology &Therapeutics, EarlyView.
We evaluated long‐term outcomes following nucleos(t)ide analogue discontinuation in HBeAg‐negative chronic hepatitis B. HBsAg loss was infrequent. Early HBsAg loss occurred in patients with low end‐of‐treatment HBsAg levels and without ALT flare, whilst late HBsAg loss typically followed ALT flares and was associated with higher end‐of‐treatment HBsAg ...
Simon J. Hume, Samuel Hall, Gareth Burns, Sara Vogrin, Daniel Tassone, Paul Desmond, Dilip Ratnam, Miriam T. Levy, Rohit Sawhney, Amanda Nicoll, Zina Valaydon, Simone I. Strasser, Meng Ngu, Marie Sinclair, Chris Meredith, Gayle V. Matthews, Kumar Visvanathan, Jacinta A. Holmes, Alexander J. Thompson   +18 more
wiley   +1 more source

Evaluation of fully automated chemiluminescent enzyme immunoassays for hepatitis B core-related antigen components, phosphorylated and non-phosphorylated hepatitis B core antigens: clinical significance and dynamics during hepatitis B e antigen seroconversion. [PDF]

J Clin Microbiol
Suzuki T, Ohue C, Arai O, Inose Y, Nagaoka K, Ogawa S, Inoue T, Matsuura K, Aoyagi K, Yagi S, Tanaka Y.   +10 more
europepmc   +1 more source

Prevalence of the Hepatitis B Surface Antigen in Various Liver Diseases among Koreans Demonstrated by Orcein Staining of 614 Biopsies

, 1978
Jae Yun Ro, Chan Il Park, Yoo Bock Lee
openalex   +1 more source

Hepatitis B Immunoglobulins Withdrawal in Hepatitis B Virus Mono‐Infected Liver Transplant Recipients: An Italian Multicentre Prospective Study

Alimentary Pharmacology &Therapeutics, EarlyView.
Hepatitis B immunoglobulins withdrawal in hepatitis B virus mono‐infected liver transplant recipients: An Italian multicentre prospective study. ABSTRACT Background & Aims Despite recommendations from scientific societies that hepatitis B immunoglobulin (HBIG) can be safely discontinued, centres across Europe continue to use the combination nucleoside ...
Raffaella Viganò, Alessandro Loglio, Clara Dibenedetto, Paola Carrai, Silvia Martini, Ilaria Lenci, Bianca Magro, Sara Conti, Paolo Angelo Cortesi, Chiara Mazzarelli, Chiara Becchetti, Giovanni Perricone, Monica Cucco, Marco Carbone, Donatella Cocchis, Elisa Farina, Luisa Pasulo, Mauro Viganò, Michele Sagasta, Elisabetta Degasperi, Davide Ghinolfi, Pietro Lampertico, Stefano Fagiuoli, Luca Saverio Belli, on behalf of the INSIGHT‐B study group   +24 more
wiley   +1 more source

Recent Advancements in Non-Invasive Vaccination Strategies. [PDF]

Vaccines (Basel)
Gulani M, Arte T, Ferguson A, Pasupuleti D, Adediran E, Harsoda Y, Nicolas McCommon A, Gala R, D'Souza MJ.   +8 more
europepmc   +1 more source