Results 171 to 180 of about 16,498,742 (308)

Italian Patients Journey for Gene Therapy in Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno, Gaia Spadarella, Alessandra Borchiellini, Anna Borrelli, Andrea Buzzi, Giancarlo Castaman, Michele Cecchi, Raimondo De Cristofaro, Vincenzo La Mura, Angelo Lupi, Giuseppe Malcangi, Maria Elisa Mancuso, Maria Francesca Mansueto, Cristina Santoro, Rita Carlotta Santoro, Luigi Piero Solimeno, Annarita Tagliaferri, Ezio Zanon, Isabella Garagiola, Flora Peyvandi   +19 more
wiley   +1 more source

Hepatitis B : are you at risk? [Amharic]

Hepatitis B : are you at risk? [Amharic]AmharicThese sheets have the English translation on the back.cdc/gov/knowhepatitisBFactSheet-HepBAreYouAtRisk_amh-eng ...

core  

Anti‐Integrin αvβ6 Autoantibodies as Diagnostic and Monitoring Biomarkers for Pediatric‐Onset Primary Sclerosing Cholangitis

Hepatology Research, EarlyView.
Levels of anti‐integrin αvβ6 antibodies were significantly higher in pediatric‐onset primary sclerosing cholangitis (PSC) than in autoimmune hepatitis (AIH) and may reflect disease activity. These antibodies may serve as a novel biomarker for distinguishing PSC from AIH and for monitoring disease progression.
Yukako Maeda, Shuichiro Umetsu, Eitaro Hiejima, Mitsuyoshi Suzuki, Itaru Iwama, Takeshi Kimura, Sonoko Kondo, Ayano Inui, Hiroki Kondou, Tatsuya Okamoto, Takashi Ito, Hiroyuki Shirahase, Kazushi Izawa, Takahiro Yasumi, Takeshi Kuwada, Masahiro Shiokawa, Hiroshi Seno, Junko Takita   +17 more
wiley   +1 more source

Smart nanoparticle vaccines integrate nanotechnology artificial intelligence and immunoengineering for precision immunization. [PDF]

Discov Nano
Morshedi I, Roodaki Z, Gheibi P, Zamani G, Jaberi A, Hasan J, Chaloob S, Teymourzadeh M, KarkonShayan S.   +8 more
europepmc   +1 more source

Hepatitis B : are you at risk? [Arabic]

Hepatitis B : are you at risk? [Arabic]ArabicThese sheets have the English translation on the back.cdc/gov/knowhepatitisBFactSheet-HepBAreYouAtRisk_arabic-eng ...

core  

Hepatitis B Virus Infection Status in Japanese Children Prior to Universal Vaccination: Sustained Effectiveness of Mother‐to‐Child Transmission Prevention and Residual Infection Burden

Hepatology Research, EarlyView.
ABSTRACT Aim To evaluate the effectiveness of prevention of mother‐to‐child transmission (PMTCT) over 25 years, we conducted a nationwide epidemiological survey through a comprehensive assessment of hepatitis B virus (HBV) markers. Methods Two cohorts were recruited before universal vaccination: children aged 9–10 years undergoing school health ...
Aiko Sakai, Yasuhito Tanaka, Hiroshi Yotsuyanagi, Masaya Sugiyama, Ichiro Morioka, Kiyotaka Kosugiyama, Kimiaki Uetake, Tomohiro Katsuta, Atsushi Imamura, Tomoko Takano, Hitoshi Tajiri, Akihito Ishida, Kosuke Ushijima, Yumiko Nakashima, Hiroyuki Moriuchi, Shinji Iwane, Kota Sawada, Yosuke Shimizu, Yukari Uemura, Manabu Tagawa, Masashi Mizokami, Ryo Sumazaki   +21 more
wiley   +1 more source

An Approach to Antibody-Mediated Rejection in Pediatric Liver Transplantation. [PDF]

Pediatr Transplant
Jaramillo C, Randhawa P, Narang A, Gareau AJ, Weckwerth J, Mavis A, Mazariegos G, Furuya K, Kerkar N.   +8 more
europepmc   +1 more source

Toward a Synthetic Data Revolution: Diffusion Model‐Enhanced Hepatocellular Carcinoma Prediction in Steatotic Liver Disease

Hepatology Research, EarlyView.
ABSTRACT Aim Steatotic liver disease (SLD) encompasses a heterogeneous spectrum with varying risks of hepatocellular carcinoma (HCC). Limited sample sizes limit the development of predictive models, particularly for rare outcomes. This study evaluated whether generative artificial intelligence (AI)‐based synthetic data augmentation can enhance HCC risk
Masaya Sato, Takuma Nakatsuka, Yuki Matsushita, Takuma Kaneko, Keisuke Mabuchi, Tomoharu Yamada, Kazuya Okushin, Tatsuya Minami, Yotaro Kudo, Satoshi Kodera, Kazuhiko Koike, Mitsuhiro Fujishiro, Ryosuke Tateishi   +12 more
wiley   +1 more source

Hepatitis B virus core immunoglobulin M: false positive more common than true. [PDF]

J Clin Microbiol
Landry ML, Bernard PE.
europepmc   +1 more source

Proteomic Analysis of Serum Extracellular Vesicles Revealed Fibulin‐3 as a Novel Predictive Biomarker for Hepatocellular Carcinoma in Patients With Chronic Hepatitis B

Hepatology Research, EarlyView.
We carried out proteomic analysis of serum extracellular vesicles to identify biomarkers predictive of hepatocellular carcinoma (HCC) development in patients with chronic hepatitis B receiving nucleos(t)ide analog therapy. Candidate proteins identified through proteomic analysis were subsequently quantified in serum by ELISA.
Emi Sometani, Kazuhiro Murai, Hayato Hikita, Jihyun Sung, Satoshi Muraoka, Hidenori Toyoda, Satoshi Tanaka, Takayuki Miyake, Shinji Kuriki, Kenji Fukumoto, Satoshi Shigeno, Yuta Myojin, Kazuki Maesaka, Kumiko Shirai, Yuki Makino, Yuki Tahata, Yoshinobu Saito, Takahiro Kodama, Ryotaro Sakamori, Jun Adachi, Tomomi Yamada, Tetsuo Takehara   +21 more
wiley   +1 more source