Overlap of Primary Biliary Cholangitis and Systemic Sclerosis: A Case of Reynolds Syndrome
ABSTRACT Reynolds Syndrome should be suspected in CREST patients with persistent cholestatic liver enzymes, since delayed diagnosis allows portal hypertension and variceal bleeding to develop. Early anti‐mitochondrial antibody screening and prompt ursodeoxycholic acid therapy improve outcomes, and these patients need multidisciplinary follow‐up for ...
Ali Gohar +9 more
wiley +1 more source
Immune and Endothelial-Related Extracellular Vesicles Are Associated with Corticosteroid Response and Mortality in Alcohol-Associated Hepatitis. [PDF]
Guinart-Cuadra A +23 more
europepmc +1 more source
Disulfiram‐Induced Hepatotoxicity in a Patient With Alcohol Use Disorder: A Case Report
ABSTRACT Disulfiram can cause severe and potentially fatal hepatotoxicity, particularly in patients with preexisting liver disease. In Bhutan, where alcohol‐related liver disease represents a major public health burden and pharmacological options for relapse prevention remain limited, careful patient selection, hepatic assessment, and early monitoring ...
Sonam Wangchuk +2 more
wiley +1 more source
Virus Biomimetic-Delivery Systems for the Production of Vaccines. [PDF]
Barbinta-Patrascu ME, Negut I, Bita B.
europepmc +1 more source
ABSTRACT HLH must be suspected in liver transplant patients who exhibit fever, cytopenia, hyperferritinemia, and dysfunction of the graft. HLH‐2004 guidelines and H‐score assessment early on will aid in early diagnosis and management, although prognosis remains poor when there are opportunistic infections.
Saif Ali Malik +5 more
wiley +1 more source
Hepatitis B Surface Antigen Loss and Improved Clinical Outcomes in US Individuals With Chronic Hepatitis B Virus Infection. [PDF]
Drysdale M +9 more
europepmc +1 more source
Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong +3 more
wiley +1 more source
Exceeding expectations: factors contributing to the potency of human papillomavirus vaccines. [PDF]
Schiller JT +5 more
europepmc +1 more source
ABSTRACT Background and Aims Hepatitis B virus (HBV) infection is a significant chronic infection in pediatric patients. Vaccination induces production of anti‐Hepatitis B surface antibodies, which serve as markers of protective immunity. Given the long‐term risks of cirrhosis and hepatocellular carcinoma during adulthood, this study aimed to assess ...
Erfanehsadat Shahim +7 more
wiley +1 more source
Lipid Nanoparticle-Encapsulated PolyI:C as an Adjuvant Enhances Both Humoral and Cellular Immune Responses to the Hepatitis B Vaccine. [PDF]
Zhao Z +5 more
europepmc +1 more source

