Therapeutic hepatitis B vaccine employing DNA prime - MVA boost scheme requires additional priming with recombinant HBsAg to elicit an adequate antibody response. [PDF]
Kerth HA +15 more
europepmc +1 more source
Single‐cell and paired V(D)J profiling show that paediatric adenoid hypertrophy features expanded proliferative germinal‐centre B cells with impaired maturation. Abstract Objectives To characterise the immune cellular landscape and paired B‐cell and T‐cell receptor repertoires of hypertrophic adenoids in children with obstructive sleep apnoea.
Chao Wang +6 more
wiley +1 more source
Combined HBsAg and anti-HBc testing is required to estimate hepatitis B virus seroprevalence in a low-endemic country: findings from a nationwide population-based serosurvey, Belgium, 2020. [PDF]
Furquim d'Almeida A +8 more
europepmc +1 more source
EHA Guidelines on management of chronic lymphocytic leukemia and Richter transformation
Abstract Previous editions of the European guidelines for the management of chronic lymphocytic leukemia (CLL) were developed by experts in CLL under the auspices of the European Society for Medical Oncology (ESMO). These previous editions have served as a reference text for many physicians caring for patients with CLL.
Barbara Eichhorst +13 more
wiley +1 more source
In silico design of novel recombinant antigens containing immunologically relevant regions of wild-type and escape mutant variants of HBsAg. [PDF]
Workneh YA +5 more
europepmc +1 more source
ABSTRACT Background and Aims Frequent blood donation can significantly increase the risk of iron deficiency, influenced by demographic, dietary, environmental, and genetic factors. This study aims to evaluate the association between iron deficiency and specific genetic variations (HIF‐1α (rs11549465; P582S), TMPRSS6 (rs855791; V736A), and ABO (rs651007)
Mohammad Pouya Samiee +3 more
wiley +1 more source
Precore/core mutation relatedness to viral reactivation in patients undergoing targeted therapy for hepatitis B virus-related hepatocellular carcinoma. [PDF]
Abdulrahman MS +4 more
europepmc +1 more source
ABSTRACT Background This study aimed to investigate the epidemiological trends, age‐ and sex‐related patterns, and clinical and immunological characteristics of Epstein–Barr virus (EBV) infection among febrile children. Methods We analyzed EBV DNA data from 9151 febrile children and serological antibody profiles from 6934 cases.
Hao Zhou +4 more
wiley +1 more source
Diagnostic performance of four hepatitis-B surface antigen conformité Européenne (CE) marked and one WHO prequalified rapid diagnostic tests in Uganda. [PDF]
Baliruno LN +4 more
europepmc +1 more source

