Results 221 to 230 of about 102,119 (362)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Acute Hemorrhagic Leukoencephalitis With Active Hepatitis B Virus Infection: A Case Report. [PDF]

Neurol Neuroimmunol Neuroinflamm
Mirg S, Parihar J, Tripathi M, Vibha D, Singh RK, Elavarasi A, Das A, Garg A, Brijwal M, Sharma MC.   +9 more
europepmc   +1 more source

Tumor Endothelial Cells Induce M2 Macrophage Polarization via IL‐4, Enhancing Tumor Growth in Hepatocellular Carcinoma

Cancer Science, EarlyView.
Tumor endothelial cells (TECs) promote the polarization of macrophages to M2 subtype by secreting IL‐4. Downregulation of IL‐4 in TECs suppressed M2 polarization and tumor progression. A high abundance of both TECs and M2 macrophages in HCC specimens is associated with poor prognosis.
Daijiro Matoba, Takehiro Noda, Shogo Kobayashi, Yoshihiro Sakano, Kenichi Matsumoto, Chihiro Yamanaka, Kazuki Sasaki, Shinichiro Hasegawa, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Hidenori Takahashi, Tadafumi Asaoka, Junzo Shimizu, Hisashi Wada, Yuichiro Doki, Hidetoshi Eguchi   +17 more
wiley   +1 more source

CAR-T cell engineered with TCR-like antibody specific for HBV surface antigen epitope E183-91/HLA-A *0201 exhibit potent activity against HBV-HCC. [PDF]

Oncoimmunology
Wang F, Li J, Huang Y, Yan F, Gao H, Zhou W, Gu X, Li D, Zhang Y, Li J, Yang Y, Yang J, Zhang M, Yang J, Qi S, Wang W.   +15 more
europepmc   +1 more source

Distinct H-2-linked regulation of T-cell responses to the pre-S and S regions of the same hepatitis B surface antigen polypeptide allows circumvention of nonresponsiveness to the S region.

, 1985
David R. Milich, M McNamara, A. McLachlan, George B. Thornton, Francis V. Chisari   +4 more
openalex   +1 more source

Delayed development of antibody to hepatitis B surface antigen after symptomatic infection with hepatitis B virus [PDF]

, 1981
B. J. McMahon, Thomas R. Bender, K R Berquist, Marshall T. Schreeder, A Harpster   +4 more
openalex   +1 more source

Comparative Cytokine and Histology Studies on HPV and Other Viral Vaccinations: No Pathogenicity of HPV Vaccine Adjuvants

Cancer Science, EarlyView.
Anti‐HPV vaccine activists claimed that aluminum (Al) adjuvants in HPV vaccines could cause immune abnormalities, leading to neurological diseases. We evaluated the cytokine and histology profiles following administrations of HPV vaccines and other viral vaccines containing adjuvants.
Reona Shiro, Fumitaka Sato, Seiichi Omura, Ah‐Mee Park, Cong Thanh Nguyen, Ijaz Ahmad, Sandesh Rimal, Koji Kinoshita, Noriomi Matsumura, Ikuo Tsunoda   +9 more
wiley   +1 more source

Longitudinal observation of chronic domestic cat hepadnavirus infection in cats with evidence of extrahepatic involvement. [PDF]

J Feline Med Surg
Wardhani SW, Lacharoje S, Kasantikul T, Piewbang C, Techangamsuwan S.   +4 more
europepmc   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Detection Rates of Hepatitis B Surface and Core-related Antigens Using Novel Highly Sensitive Assays in Chronic Hepatitis B Patients With Hepatitis B Surface Antigen Seroclearance

Gastro Hep Advances
Taiki Okumura, Satoru Joshita, Yoshiyuki Kitamura, Haruka Sagi, Takeji Umemura   +4 more
doaj   +1 more source