Predominance of HBV Genotype B and HDV Genotype 1 in Vietnamese Patients with Chronic Hepatitis
Hepatitis delta virus (HDV) coinfection will additionally aggravate the hepatitis B virus (HBV) burden in the coming decades, with an increase in HBV-related liver diseases.
Nghiem Xuan Hoan+14 more
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Detecting Hepatitis B Surface Antigen Mutants
Hepatitis B viral mutants can emerge in patients as a result of selection pressure from either immune response or treatment options. Mutations that occur within the immunodominant epitopes of hepatitis B surface antigen (HBsAg) allow mutant virus to propagate in the presence of a neutralizing immune response, while wild-type virus is reduced to ...
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Clinical features of chronic hepatitis B patients with low hepatitis B surface antigen levels and determinants of hepatitis B surface antigen seroclearance [PDF]
AbstractBackground and AimA low hepatitis B surface antigen (HBsAg) level is reported to be predictive of future HBsAg seroclearance. A hospital‐based cohort study was conducted to clarify the clinical features of patients with low HBsAg levels and to demonstrate the usefulness of low HBsAg levels for predicting HBsAg seroclearance.MethodsA total of ...
Hideaki Taniguchi+4 more
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Predictive value of HBeAg titer dynamics for HBsAg clearance in pediatric chronic hepatitis B
IntroductionAchieving functional cure of chronic hepatitis B (CHB), characterized by the loss of HBV DNA and HBsAg, remains challenging in adults but demonstrates higher success rates in children.
Sukjin Hong+8 more
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Serosurveillance of vaccine preventable diseases and hepatitis C in healthcare workers from Lao PDR. [PDF]
BACKGROUND AND AIMS:Healthcare workers (HCW) have an increased risk of exposure to infectious diseases and are a potential source of infections for their patients.
Antony P Black+5 more
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Immune response to hepatitis B surface antigen [PDF]
A total of 69 persons were investigated for assessment of cell-mediated and humoral immunity to hepatitis B surface antigen (HBsAg). Three groups, each consisting of 20 normal persons, 20HBsAg carriers, and 20 convalescent hepatitis B patients, were studied for HBsAg, anti-HBs, and leukocyte migration inhibition with purified HBsAg. Sequential sampling
A. B. Ibrahim+2 more
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Intracellular Dynamics of Hepatitis B Virus Infection: A Mathematical Model and Global Sensitivity Analysis of Its Parameters [PDF]
Analysis of cell population can reveal the average information about the viral infection in host whereas single-cell analysis can capture the individual consideration. Single-cell analysis can also provide new ways to explore viral diversities and identify the intrinsic extreme phenotype of the cells. In this study, a single-cell hepatitis B virus (HBV)
arxiv
Mathematical model of immune response to hepatitis B [PDF]
A new detailed mathematical model for dynamics of immune response to hepatitis B is proposed, which takes into account contributions from innate and adaptive immune responses, as well as cytokines. Stability analysis of different steady states is performed to identify parameter regions where the model exhibits clearance of infection, maintenance of a ...
arxiv +1 more source
Method for identification of condition-associated public antigen receptor sequences [PDF]
Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system. The development of immunoglobulin receptor repertoire sequencing methods makes it possible to perform repertoire-wide disease association studies of antigen receptor sequences.
arxiv +1 more source
This study was carried out to determine the prevalence of hepatitis B and C infections among HIV/AIDS patients attending Aminu Kano Teaching Hospital, Kano, Nigeria. A hundred and fifty HIV patients attending the HIV Clinic at the hospital were screened
Edia-Asuke, U.A., Usman, H.S.
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