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Hepatitis B vaccine development and implementation

Human Vaccines & Immunotherapeutics, 2020
Vaccination against hepatitis B is the most effective strategy to control HBV infection. The first licensed hepatitis B vaccine was developed by the purification of hepatitis B surface antigen (HBsAg) from plasma of asymptomatic HBsAg carriers. Then, the
Hong Zhao, Xiaoying Zhou, Yi-Hua Zhou
doaj   +2 more sources

Safety and Preliminary Immunogenicity of Recombinant Hepatitis B (Bio Farma) Vaccine in Adults and Children: A Phase 1 Clinical Trial [PDF]

Althea Medical Journal, 2023
Background: In order to fulfil the requirements of the national immunization program and sustain the production capacity of the monovalent Hepatitis B vaccine, this study aimed to assess the safety and immunogenicity of the recombinant Hepatitis B ...
Eddy Fadlyana, Rodman Tarigan, Kusnandi Rusmil, Rini Mulia Sari, Cissy B Kartasmita, Behesti Zahra Mardiah, Muhammad Gilang Dwi Putra   +6 more
doaj   +3 more sources

Influences of obesity on the immunogenicity of Hepatitis B vaccine

Human Vaccines & Immunotherapeutics, 2017
Objective: Hepatitis B vaccine is regarded as the most effective method for the prevention of hepatitis B virus (HBV) infection. However, several factors such as age, body mass index and immunocompetent state have been reported to be associated with ...
Fang Liu, Zhirong Guo, Chen Dong
doaj   +2 more sources

Hepatitis B vaccine knowledge and self-reported vaccination status among healthcare workers in a conflict region in northeastern Nigeria

Therapeutic Advances in Vaccines and Immunotherapy, 2020
Background Hepatitis B virus (HBV) infection is highly endemic in Nigeria. The primary objective of this study is to describe the knowledge, self-reported vaccination status, and intention of healthcare workers to receive hepatitis B vaccine at a ...
Farouq Muhammad Dayyab, Garba Iliyasu, Bashir Garba Ahmad, Abdulaziz Tijjani Bako, Sepu Saraya Ngamariju, Abdulrazaq Garba Habib   +5 more
doaj   +2 more sources

Uptake of the hepatitis B vaccine among brothel-based female sex workers in Kampala, Uganda [PDF]

BMC Public Health
Background Hepatitis B is a significant health problem worldwide, particularly among high-risk groups such as female sex workers (FSWs). In Uganda, it is highly recommended that FSWs receive the hepatitis B vaccine.
Joana Nakiggala, Mathias Lwenge, Doreen Nakalembe, Bridget Nagawa Tamale, Aisha Nalugya, Jovan Galiwango, Junior Mike Wejuli, Kenneth Tebandeke, John Bosco Isunju, Richard K. Mugambe, Tonny Ssekamatte   +10 more
doaj   +2 more sources

Hepatitis B Vaccine: Four Decades on [PDF]

Vaccines
Hepatitis B virus is a substantial contributor to cirrhosis and hepatocellular carcinoma (HCC) globally. Vaccination is the most effective method for prevention of hepatitis B and its associated morbidity and mortality, and the only method to prevent ...
Maria Mironova, Marc G. Ghany
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Adverse event reporting following immunization of hepatitis B vaccine: A 13-year review [PDF]

Human Vaccines & Immunotherapeutics
Hepatitis B vaccination is the most effective means of interrupting HBV transmission. Although the hepatitis B vaccine is very effective and safe, adverse events following immunization do occur and need to be reported so that problems can be identified ...
Xiaoying Gong, Quanjun Fang, Jianyue Zhong, Canjie Zheng, Zhiying Yin   +4 more
doaj   +2 more sources

Overview of Hepatitis B Vaccine Non-Response and Associated B Cell Amnesia: A Scoping Review [PDF]

Pathogens
Background: The advent of the hepatitis B vaccine has achieved tremendous success in eradicating and reducing the burden of hepatitis B infection, which is the main culprit for hepatocellular carcinoma—one of the most fatal malignancies globally ...
Nura Bello, Shuaibu A. Hudu, Ahmed S. Alshrari, Mustapha U. Imam, Abdulgafar O. Jimoh   +4 more
doaj   +2 more sources

Knowledge of Hepatitis B Vaccine among Operating Room Personnel in Nigeria and Their Vaccination Status [PDF]

Hepatitis Research and Treatment, 2011
Background. Hepatitis B virus (HBV) infection is a well recognised occupational health hazard preventable by vaccination. Objectives. To determine the knowledge of operating room personnel (ORP) in Nigeria about the Hepatitis B vaccine, their perception ...
Alegbeleye, Bamidele J., Bwala, Kefas John, Dongo, Andrew, Irekpita, Eshiobo, Kesieme, Emeka B., Uwakwe, Kenechi   +5 more
core   +3 more sources

Hepatitis B Vaccine Nonresponse and Associated Risk Factors: Insights From a Cohort Study [PDF]

Journal of Tropical Medicine
Hepatitis B virus (HBV) infection remains a critical global health issue, particularly in high-burden regions with substantial global morbidity and mortality.
Shuaibu Abdullahi Hudu, Abdulgafar Olayiwola Jimoh, Sa’adatu Haruna Shinkafi, Albashir Tahir, Ahmed Subeh Alshrari, Muhammad Tukur Umar, Abdulmajeed Yunusa, Nura Bello, Nura Abubakar   +8 more
doaj   +2 more sources