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A controlled clinical trial of the efficacy of the hepatitis B vaccine (heptavax B): A final report [PDF]
W. Szmuness+4 more
openalex +2 more sources
The duration of protection from hepatitis B vaccination in children and adults is not known. In 1981, we used three doses of plasma‐derived hepatitis B vaccine to immunize a cohort of 1578 Alaska Native adults and children from 15 Alaska communities who ...
M. Bruce+13 more
semanticscholar +1 more source
Immunogenicity and Safety of a 3-Antigen Hepatitis B Vaccine vs a Single-Antigen Hepatitis B Vaccine
Key Points Question What is the immunogenicity and safety of a 3-antigen hepatitis B virus (HBV) vs a single-antigen HBV vaccine among young adults? Findings This randomized clinical trial of 2838 participants found that the 3-antigen HBV vaccine was ...
T. Vesikari+22 more
semanticscholar +1 more source
Abstract Hepatitis B is caused by the hepatitis B virus (HBV), which infects the liver and may lead to chronic liver disease, including cirrhosis and hepatocellular carcinoma. HBV represents a worldwide public health problem, causing major morbidity and mortality.
Pattyn, Jade+3 more
openaire +4 more sources
Hepatitis B vaccine development and implementation
Vaccination against hepatitis B is the most effective strategy to control HBV infection. The first licensed hepatitis B vaccine was developed by the purification of hepatitis B surface antigen (HBsAg) from plasma of asymptomatic HBsAg carriers. Then, the
Hong Zhao, Xiaoying Zhou, Yihua Zhou
semanticscholar +1 more source
Association of Number of Doses With Hepatitis B Vaccine Series Completion in US Adults
Key Points Question Is completion of an adult hepatitis B virus vaccine series higher among recipients of a 2-dose vaccine compared with recipients of a 3-dose vaccine?
K. Bruxvoort+12 more
semanticscholar +1 more source
Background Hepatitis B virus (HBV) infection is highly endemic in Nigeria. The primary objective of this study is to describe the knowledge, self-reported vaccination status, and intention of healthcare workers to receive hepatitis B vaccine at a ...
F. Dayyab+5 more
semanticscholar +1 more source
Hepatitis B virus is a substantial threat to global health, with 360 million people chronically infected and more than 500 000 deaths each year from fulminant hepatitis, cirrhosis, and liver cancer.1 2 After a call by the World Health Organization for the global introduction of vaccine prevention programmes by 1997,3 82% of countries in the world had ...
openaire +5 more sources
Hepatitis B (HepB) vaccination is the primary means of preventing infections and complications caused by hepatitis B virus (HBV). On February 21, 2018, the Advisory Committee on Immunization Practices (ACIP) recommended Heplisav-B (HepB-CpG), a yeast ...
S. Schillie+5 more
semanticscholar +1 more source
Hepatitis B Vaccine and Immunoglobulin: Key Concepts
Hepatitis B virus (HBV) immunization is safe and has been accepted worldwide as a routine practice. The target of such vaccination is to induce the immune response in the host, resulting in the prevention of replication of HBV.
S. Das+5 more
semanticscholar +1 more source