Results 41 to 50 of about 168,078 (280)

Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs [PDF]

, 2012
Hepatitis E virus (HEV), the causative agent of hepatitis E, is primarily transmitted via the fecal-oral route through contaminated water supplies, although many sporadic cases of hepatitis E are transmitted zoonotically via direct contact with infected ...
Córdoba, Laura, Dryman, Barbara A, Kenney, Scott P, Meng, Xiang-Jin, Opriessnig, Tanja, Sanford, Brenton J   +5 more
core   +1 more source

Immune response to vaccines in children with celiac disease [PDF]

, 2017
Celiac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and ...
ANANIA, Caterina, CHIESA, CLAUDIO, OLIVERO, FRANCESCA, PACIFICO, Lucia, Spagnolo, Alessandra   +4 more
core   +1 more source

Epidemiological patterns of hepatitis B virus (HBV) in highly endemic areas [PDF]

, 1996
This paper uses meta-analysis of published data and a deterministic mathematical model of hepatitis B virus (HBV) transmission to describe the patterns of HBV infection in high endemicity areas.
W. J. Edmunds, G. F. Medley, D. J. Nokes, C. J. O'Callaghan, H. C. Whittle, A. J. Hall, Reniers, Sokal, Pearce, Tong, Pongpipat, Gebreselassie, Overby, Prozesky, Swenson, Anderson, Milne, Sobeslavsky, Schweitzer, Shiraki, Barin   +20 more
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Hepatitis Vaccines

Vaccines, 2016
Viral hepatitis is a serious health problem all over the world. However, the reduction of the morbidity and mortality due to vaccinations against hepatitis A and hepatitis B has been a major component in the overall reduction in vaccine preventable ...
Sina Ogholikhan, Kathleen B. Schwarz
doaj   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

Hepatitis B vaccine knowledge and self-reported vaccination status among healthcare workers in a conflict region in northeastern Nigeria

Therapeutic Advances in Vaccines and Immunotherapy, 2020
Background Hepatitis B virus (HBV) infection is highly endemic in Nigeria. The primary objective of this study is to describe the knowledge, self-reported vaccination status, and intention of healthcare workers to receive hepatitis B vaccine at a ...
Farouq Muhammad Dayyab, Garba Iliyasu, Bashir Garba Ahmad, Abdulaziz Tijjani Bako, Sepu Saraya Ngamariju, Abdulrazaq Garba Habib   +5 more
doaj   +1 more source

HBsAg-vectored DNA vaccines elicit concomitant protective responses to multiple CTL epitopes relevant in human disease. [PDF]

, 2008
Vaccines capable of controlling neoplastic and infectious diseases which depend on the cellular immune response for their resolution, have proven difficult to develop.
Allan Gould, Dekun Chen, Jacqueline Kattenbelt, Melanie Barnes, Michael Mather, Oscar Haigh, Robert R. Tindle, Scott Thomson   +7 more
core   +1 more source

Modelling the hepatitis B vaccination programme in prisons [PDF]

, 2005
A vaccination programme offering hepatitis B (HBV) vaccine at reception into prison has been introduced into selected prisons in England and Wales. Over the coming years it is anticipated this vaccination programme will be extended.
Andrews, Nicholas J., Edmunds, W. John, Gay, N. J., Gilbert, R. L., Gill, O. N., Hope, V. D., Piper, M., Sutton, A. J.   +7 more
core   +2 more sources

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source