Results 51 to 60 of about 12,657,081 (210)

Overview of Hepatitis B Vaccine Non-Response and Associated B Cell Amnesia: A Scoping Review

Pathogens
Background: The advent of the hepatitis B vaccine has achieved tremendous success in eradicating and reducing the burden of hepatitis B infection, which is the main culprit for hepatocellular carcinoma—one of the most fatal malignancies globally ...
Nura Bello, Shuaibu A. Hudu, Ahmed S. Alshrari, Mustapha U. Imam, Abdulgafar O. Jimoh   +4 more
doaj   +1 more source

Hepatitis B sero-prevalence in children under 15 years of age in South Africa using residual samples from community-based febrile rash surveillance.

PLoS ONE, 2019
Introduction and methodsHepatitis B is a vaccine preventable disease and is notifiable in South Africa. Hepatitis B vaccination was incorporated into the Expanded Programme on Immunisation in South Africa in 1995.
Nishi Prabdial-Sing, Lillian Makhathini, Sheilagh Brigitte Smit, Morubula Jack Manamela, Nkengafac Villyen Motaze, Cheryl Cohen, Melinda Shelley Suchard   +6 more
doaj   +1 more source

Long-term protection at 20–31 years after primary vaccination with plasma-derived hepatitis B vaccine in a Chinese rural community

Human Vaccines & Immunotherapeutics, 2020
Background: To assess the long-term protection conferred by plasma-derived hepatitis B vaccine at 20–31y after primary immunization during infancy in Chinese rural community.
Jing-Chen Ma, Zhi-Wei Wu, Hai-Song Zhou, Zhao Gao, Zhi-Yong Hao, Fei Jin, Yan-Hong Zhang, Min-Jie Li, Feng Wang, Qi Li, Sheng-Li Bi, Yu-Liang Zhao   +11 more
doaj   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Study on the Impacts of Haemoglobin Genotype on Hepatitis B vaccine Response among Vaccinated Individuals within Bauchi State, Nigeria

UMYU Journal of Microbiology Research
Hepatitis B virus (HBV) infection is one of the viral diseases of public health concern globally.  It causes liver cirrhosis and hepatocellular carcinoma.
Thomas, K. M., Titus Mispha
doaj   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Introduction of universal infant hepatitis B immunisation in the UK– paving the way to elimination

Human Vaccines & Immunotherapeutics, 2019
In May 2016, the World Health Assembly ratified the first ever Global Health Sector Strategy (GHSS) on Viral Hepatitis to eliminate viral hepatitis as a public health threat by 2030.
Sema Mandal
doaj   +1 more source

Safety and efficacy of the RTS,S/AS01E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial. [PDF]

, 2011
BACKGROUND\ud \ud The RTS,S/AS01(E) candidate malaria vaccine is being developed for immunisation of infants in Africa through the expanded programme on immunisation (EPI).
Abdulla, Salim, Sillman, Marla, Tanner, M., Osei-Kwakye, Kingsley, Vekemans, J., Solange Soulanoudjingar, Apanga, Stephen, Adjei, George, Agnandji, S., Grace Mwangoka, Jose F Fernandes, Leach, Amanda, Issifou, Saadou, Owusu-Agyei S.,, Didier Lapierre, Lapierre, Didier, Chandramohan, Daniel, Dosoo, D., Dubois, Marie-Claude, Boahen, Owusu, Joe Cohen, Greenwood, B., Kayan, K., Lyimo, John, Apanga, S., Boahen, O., Kwaku Poku Asante, Loucq, Christian, Maria Paricek, Salim Abdulla, Asante, Kwaku Poku, Carter, T., Owusu-Agyei, Seth, Marcel Tanner, Kremsner, Peter, Marie-Claude Dubois, Evans Kwara, Marc Lievens, Kayan, Kingsley, Asante-Poku A.,, Owusu, R., Jongert, Erik, Vansadia, P., Tigani Madi, Nahya Salim, Kingsley Kayan, Leach, A., Lievens, Marc, Madi, Tigani, Chikawe, Maria, Paricek, Maria, Savarese, B., Stephen Apanga, Amanda Leach, Agnandji, Selidji, Vansadia, Preeti, Owusu, Ruth, Daniel Chandramohan, Fernandes, Jose F, Jongert, E., Salim, N., Cohen, J., Abdulla, S., Erik Jongert, Christian Loucq, Kwara, Evans, George Adjei, Preeti Vansadia, Möller, Tina, Mwangoka, G., John Lyimo, Soulanoudjingar, Solange, Greenwood, Brian, Hounkpatin, A. B., Marla Sillman, Cohen, Joe, Saadou Issifou, Issifou, S., Osei-Kwakye K.,, Owusu Boahen, Barbara Savarese, Maria Chikawe, Kwara, E., Moller, T., Hounkpatin, Aurore B, Lell, Bertrand, Carter, Terrell, Loucq, C., Shomari, Mwanajaa, Kremsner, P., Rose Minja, Kingsley Osei-Kwakye, Tina Möller, Minja, Rose, Selidji Agnandji, Lyimo, J., Sillman, M., David Dosoo, Mwanajaa Shomari, Chikawe, M., Paricek, M., Ruth Owusu, Aurore B Hounkpatin, Minja, R., Lievens, M., Brian Greenwood, Vekemans, Johan, Tanner, Marcel, Peter Kremsner, Fernandes, J. F., Dosoo, David, Savarese, Barbara, Seth Owusu-Agyei, Mwangoka, Grace, Lapierre, D., Bertrand Lell, Madi, T., Shomari, M., Terrell Carter, Salim, Nahya, Dubois, M. C., Soulanoudjingar, S., Adjei, G., Lell, B., Chandramohan, D., Johan Vekemans   +125 more
core   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source