Results 121 to 130 of about 387,869 (336)

Making Advanced Therapies Affordable and Accessible: Two Strategic Approaches

open access: yesDeveloping World Bioethics, EarlyView.
ABSTRACT This article explores two complementary strategies for addressing the affordability and access challenges facing advanced therapies. As high development costs and limited market access have led to the withdrawal of several therapies, the article examines how these barriers create ‘valleys of death’ that prevent innovation from reaching ...
Ubaka Ogbogu, Lauren Albrecht
wiley   +1 more source

Herpes Zoster in Hematological Disorders: Pathogenesis, Risk Stratification, and Emerging Strategies for Prevention and Immunization

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background Herpes zoster (HZ), resulting from reactivation of latent varicella‐zoster virus (VZV), imposes a significant burden on immunocompromised patients, particularly those with hematological malignancies and recipients of hematopoietic stem cell transplants (HSCT).
Enrica Antonia Martino   +10 more
wiley   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

open access: yesXenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

The costs of home delivery of a birth dose of hepatitis B vaccine in a prefilled syringe in Indonesia

open access: yesBulletin of the World Health Organization, 2005
OBJECTIVE: To provide global policy-makers with decision-making information for developing strategies for immunization of infants with a birth dose of hepatitis B vaccine, this paper presents a retrospective cost analysis, conducted in Indonesia, of ...
Carol E. Levin   +4 more
doaj  

Global control of hepatitis B virus: does treatment-induced antigenic change affect immunization?

open access: yesBulletin of the World Health Organization
Since its widespread introduction, the hepatitis B vaccine has become an essential part of infant immunization programmes globally. The vaccine has been particularly important for countries where the incidence of hepatitis B virus-related hepatocellular ...
C John Clements   +5 more
doaj   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

open access: yesThe FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza   +4 more
wiley   +1 more source

Immunogenicity of a two-dose investigational hepatitis B vaccine, HBsAg-1018, using a toll-like receptor 9 agonist adjuvant compared with a licensed hepatitis B vaccine in adults.

open access: yesVaccine, 2018
S. Jackson   +10 more
semanticscholar   +1 more source

Population‐Based Molecular Surveillance of Hepatitis B Virus Genotypes in the Goto Islands, Japan: A Three Decade Study (1977–2008) of 916 Carriers

open access: yesHepatology Research, EarlyView.
ABSTRACT Aims Understanding the molecular characteristics and genotype distribution of hepatitis B virus (HBV) is essential to elucidate intra and inter community transmission routes, identify cluster cases, and assess clinical implications based on genotype‐specific virulence.
Ko Ko   +10 more
wiley   +1 more source

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