Metabolic Dysfunction‐Associated Fatty Liver Disease: From Pathogenesis to Treatment
Extracellular vesicles play a crucial role in interorgan crosstalk of adipose–liver and gut–liver axes and hold potential as therapeutic targets and drug delivery systems for metabolic dysfunction‐associated fatty liver disease (MAFLD). Abbreviations: AT: adipose tissue; EVs: extracellular vesicles; HL: healthy liver; NAFL: nonalcoholic fatty liver ...
Zhifu Cui +5 more
wiley +1 more source
Why does hepatitis B remain underprioritized? A view through lived experience. [PDF]
Ibrahim Y +10 more
europepmc +1 more source
CD8+ Tissue‐Resident Memory T Cells in Health and Disease
CD8+ TRM cells are at the center of immunity, mediating potent local innate and adaptive immune responses. While TRM cells mediate protective immunity against infections and tumors, they also contribute to pathological inflammation in autoimmune conditions.
Yu‐Han Ai +13 more
wiley +1 more source
Temporal trends of vaccination coverage in children under five in Brazil, 1998-2024. [PDF]
Rago CAP, de Novais MAP, Zucchi P.
europepmc +1 more source
De Novo Synthesis in Cancer Immunotherapy: Applications and Prospects
De novo protein design creates novel structures for cancer immunotherapy, integrating rational design principles like modularity and specificity. Leveraging computational tools, it optimizes cytokine engineering, adoptive cellular therapy, and checkpoint regulation to enhance antitumor immunity.
Yang Jin, Yanfeng Wu, Jianhua Luo
wiley +1 more source
Antibody levels and immune memory in children with kaposiform hemangioendothelioma treated with sirolimus after catch up vaccination. [PDF]
Yuan J, Ding Y, Wang Z, Su L, Li K.
europepmc +1 more source
A bibliometric analysis of immunotherapy for chronic hepatitis B: trends and hotspots prediction. [PDF]
Jin X, Tang Y, Ma Y, Li M, Gao Y.
europepmc +1 more source
ABSTRACT HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy (ART) suppresses viral replication, it does not eradicate the virus, and metabolic dysregulation persists despite treatment.
Levanco K. Asia +4 more
wiley +1 more source
Immunogenicity and safety of co-administered <i>Escherichia coli</i>-produced bivalent HPV-16/18 vaccine and hepatitis E vaccine. [PDF]
Yan R +11 more
europepmc +1 more source
ABSTRACT Panel count data occurs in a wide variety of applications, ranging from biomedical research to business, such as the number of accidents, product defects, and insurance claims. For such data under the FDA investigation, millions of reported adverse events (AEs) associated with thousands of drugs are monitored in the post‐market drug safety ...
Yizhao Zhou, Ao Yuan, Ming Tan
wiley +1 more source

