Results 181 to 190 of about 127,319 (303)

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, Volume 20, Issue 5, Page 1098-1110, May 2026.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Safe and Localized Lentiviral Gene Delivery via Injectable Mesoporous Scaffolds for Potent Antitumor Immunity

Advanced Materials, Volume 38, Issue 25, 4 May 2026.
This work introduces an injectable mesoporous silica rod scaffold that confines lentiviral vectors to the injection site, enabling localized dendritic cell recruitment and transduction. The platform sustains antigen expression, promotes robust T‐cell activation, and enhances antitumor immunity.
Thanh Loc Nguyen, Yeon‐ju Kim, Jihye Im, Dong Kwang Min, Hyunsu Shin, Thuy An Trinh, Ngoc Man Phan, Min‐jeong Son, Ji‐yeon Shim, Ye‐lim Lee, Yujeong Ha, Kwang‐il Lim, Jaeyun Kim   +12 more
wiley   +1 more source

Brief Report: Hepatitis B Vaccination Histories in Persons With HIV Needing Revaccination. [PDF]

J Acquir Immune Defic Syndr
Kang M, Umbleja T, Avihingsanon A, Cardoso SW, Kosgei J, Vigil KJ, Ngan TTD, Chakalisa U, Caruso S, Sherman KE, Marks KM.   +10 more
europepmc   +1 more source

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Intratumoral Proton Density Fat Fraction Predicts the Outcome of HAIC Combined With PD‐1 Inhibitors in Advanced Hepatocellular Carcinoma

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background and Aims This study aimed to explore the predictive value of intratumoral proton density fat fraction (PDFF) and the clinical efficacy of hepatic arterial infusion chemotherapy (HAIC) combined with anti‐programmed cell death protein 1 (anti‐PD‐1) therapy in advanced hepatocellular carcinoma (HCC).
Yujie Ye, Yunzheng Li, Yanjun Lu, Yanchao Xu, Laizhu Zhang, Yican Zhu, Huan Li, Binghua Li, Min Zhou, Decai Yu   +9 more
wiley   +1 more source

Autoimmune Hepatitis Following COVID‐19 Vaccination in a Patient With Ulcerative Colitis: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Autoimmune hepatitis (AIH) following COVID‐19 vaccination is a rare adverse event. We present the case of a 55‐year‐old male with a history of ulcerative colitis (UC) who developed AIH 3 weeks after receiving his second dose of the Pfizer–BioNTech mRNA vaccine. He presented with jaundice and significantly elevated liver enzymes. A liver biopsy
Marwah Algodi, Mohamed Nasser Elshabrawi, Mohamed Abuelazm, Ibrahim Gowaily, Omar Saab, Hatem Eltaly, Constantine Fisher   +6 more
wiley   +1 more source

Timeliness of routine vaccination among 24-35 months children in Urban Gambia. [PDF]

PLoS One
Kijera B, Sowe A, Bobb M, Jarjusey S, Manjang LF, Sillah S, Wariri O.   +6 more
europepmc   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Vaccines at the Heart of Hepatitis Elimination: Insights From the ESCMID Study Group for Viral Hepatitis (ESGVH). [PDF]

Liver Int
Săndulescu O, Şahin GÖ, Dudman SG, Said ZNA, Mondelli MU, ESCMID Study Group for Viral Hepatitis (ESGVH).   +5 more
europepmc   +1 more source

Nur77 Is Associated With Polyfunctional Properties in Virus‐Specific Human CD8+ T Cells

European Journal of Immunology, Volume 56, Issue 5, May 2026.
Nur77 is associated with a TCF‐1+ memory‐like, polyfunctional profile in virus‐specific human CD8+ T cells across acute‐resolved, vaccinated, and chronic viral infections, and its pharmacologic modulation in vitro enhances the functionality of dysfunctional HIV‐ and HBV‐specific CD8+ T cells in chronic co‐infections. ABSTRACT Human CD8+ T cells undergo
Fabiola Martel, Daniel Rincón, Caroline Passaes, Leonardo Arévalo, Marcela Torres, Natalia Ramirez, Carlos F. Narváez, Jessica F. Toro, Otto Sussmann, Manuel A. Franco, José Mateus, John Sidney, Alessandro Sette, Asier Sáez‐Cirión, Federico Perdomo‐Celis   +14 more
wiley   +1 more source