Results 181 to 190 of about 12,626,738 (303)

Cross‐tissue immune profiling of APOE ε4 reveals early dysregulation in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Apolipoprotein E (APOE) ε4 is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD), but its contribution to disease pathogenesis remains incompletely understood. METHODS Here, we integrate proteomic profiling of plasma (n = 9028), cerebrospinal fluid (n = 1099), dorsolateral prefrontal cortex (n = 720), and ...
Artur Shvetcov, Shannon Thomson, Mark E. Graham, Brittany Hauger, Jessica E. Keller, Christine J. Smoyer, Sarah E. Tague, Ann‐Na Cho, Farhad B. Imam, Varsha Krish, Global Neurodegeneration Proteomics Consortium (GNPC), Matthew K. Taylor, Jonathan D. Mahnken, Debra K. Sullivan, Joanne H. Reed, Jeffrey M. Burns, Chad Slawson, Russell H. Swerdlow, Heather M. Wilkins, Caitlin A. Finney   +19 more
wiley   +1 more source

Letter to the Editor: Bridging the immunization gap in pediatric autoimmune disorders - insights from inflammatory bowel disease and vaccine response patterns. [PDF]

World J Clin Pediatr
Al-Hussaniy HA.
europepmc   +1 more source

A descriptive case series of hepatotoxicity associated with CFTR modulators and possible relevance of pharmacogenetic polymorphisms in cystic fibrosis patients

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3257-3264, September 2026.
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are widely used in patients with cystic fibrosis and significantly improve respiratory function and quality of life. However, their effectiveness may be limited by liver damage, which sometimes leads to treatment discontinuation, and the mechanisms underlying this remain poorly ...
Clara Laffitte Redondo, Venceslas Bourdin, Abd El Kader Ait Tayeb, Sihem Benaboud, Inès Martins, Caroline Joyau, Myriam Benhamida, Isabelle Sermet‐Gaudelus, Clémence Martin, Pierre Régis Burgel, Céline Verstuyft, Laurent Chouchana, Estelle Ayme‐Dietrich   +12 more
wiley   +1 more source

Progress and challenge of hepatitis B virus mucosal vaccines. [PDF]

Virol J
Renxuan J, Hongxiang L, Daru L.
europepmc   +1 more source

Hepatitis B : are you at risk? [Hmong]

Hepatitis B : are you at risk? [Hmong]Hmong Publication No. 221613These sheets have the English translation on the back.cdc/gov/knowhepatitisBFactSheet-HepBAreYouAtRisk_hmg ...

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Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

Biotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen, Anton Du Preez van Staden, Leon M. T. Dicks   +2 more
wiley   +1 more source

Evaluation of Hepatitis B Vaccine Immunogenicity in Low-Birth-Weight Infants After Complete Immunization: The Impact of Postnatal Catch-Up Growth and Maternal-Neonatal Characteristics. [PDF]

Vaccines (Basel)
Shen L, Tang W, Xie Y, Hu R, Wang J, Qian Y, Liu H, Yu Y, Zhu Z.   +8 more
europepmc   +1 more source

The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo, Li Li, Fang Wang, Wen Liu, Yan Zhang   +4 more
wiley   +1 more source

Current Vaccination Principles and Practices in Adult Cancer Patients. [PDF]

J Clin Pract Res
Elik DB, Kıvrak EE, Yıldırım HÇ, Kılıç AU, Taşbakan M.   +4 more
europepmc   +1 more source

Hepatitis B : are you at risk? [Swahili]

Hepatitis B : are you at risk? [Swahili]Kama wewe au wazazi wako walizaliwa Afrika, ongea na daktari wako kuhusu kupimwa Hepatitisi BThese sheets have the English translation on the back.cdc/gov/knowhepatitisBFactSheet-HepBAreYouAtRisk_swa-eng ...

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