Targeting Tumor Stroma: Current Challenges and Future Directions
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang +7 more
wiley +1 more source
Why the Birth Dose Matters for Hepatitis B Vaccination. [PDF]
Girotto JE +4 more
europepmc +1 more source
The EUROmediCAT Network and Databases: A Resource for Pharmacovigilance in Pregnancy
ABSTRACT Background The evidence gap relating to the risk of congenital anomalies (CA) associated with first trimester medication exposure in pregnancy is well recognized. Aims We describe the EUROmediCAT network and databases, and the methodological approach to pregnancy pharmacovigilance.
Helen Dolk +27 more
wiley +1 more source
Evaluation of Coverage Rates of 3 Pediatric Vaccines (Measles-Mumps-Rubella, Hexavalent, and Varicella) in a Southern Italian Province (2016-2022): Effect of the Pandemic and Interregional Comparisons. [PDF]
Santoro E +10 more
europepmc +1 more source
The Management of Congenital Cytomegalovirus Infection in an Era of Universal Newborn CMV Screening
ABSTRACT The most common infectious disease responsible for paediatric developmental disability is congenital infection with human cytomegalovirus (cCMV). Many serious sequelae are caused by cCMV, including microcephaly, intracranial calcifications, neuronal migration defects, seizure disorders, developmental delay, and sensorineural hearing loss (SNHL)
Emily R. Harrison +2 more
wiley +1 more source
Correlation Analysis Between HLA Polymorphisms and Immune Response to Hepatitis B Vaccine in Children with Acute Lymphoblastic Leukemia. [PDF]
Zhang R +6 more
europepmc +1 more source
Congenital CMV and Hearing Loss—How Does it Happen and How to Prevent it
ABSTRACT Congenital cytomegalovirus (cCMV) is found worldwide and significantly contributes to permanent childhood hearing loss. CMV has been known to cause sensorineural hearing loss (SNHL) for more than half a century, and CMV‐related hearing loss has consistently been present in all childhood populations where infants with cCMV have been identified ...
Karen B. Fowler
wiley +1 more source
Review of Infections in Immunocompromised Travellers: Epidemiology, Infection Prevention and Management. [PDF]
Duduveche AE +2 more
europepmc +1 more source
Risk of Safety Events in Vitiligo Patients: A Retrospective Real‐World Data Study in the US
ABSTRACT Vitiligo is a chronic autoimmune depigmenting disease characterized by loss of pigment in the skin, hair, or both. As treatment options evolve, particularly with the emergence of oral Janus kinase inhibitors and dual Janus kinase 3/tyrosine kinase expressed in hepatocellular carcinoma family kinase inhibitor, it is essential to assess ...
Kennedy Cook +11 more
wiley +1 more source

