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DeckerMed Medicine, 2021 Chronic hepatitis B virus (HBV) infection is a major health burden worldwide, with approximately 257 million people with chronic infection. HBV is a small partially double-stranded DNA virus that replicates within the nucleus of the hepatocyte and commonly leads to chronic infection.
P. Lydyard +6 more
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Screening and Testing for Hepatitis B Virus Infection: CDC Recommendations — United States, 2023
MMWR Recommendations and Reports, 2023 Summary Chronic hepatitis B virus (HBV) infection can lead to substantial morbidity and mortality. Although treatment is not considered curative, antiviral treatment, monitoring, and liver cancer surveillance can reduce morbidity and mortality. Effective
E. Conners +15 more
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Autophagy by hepatitis B virus and for hepatitis B virus [PDF]
Autophagy, 2010 Autophagy is a catabolic process by which cells remove unwanted proteins and damaged organelles. It is important for maintaining cellular homeostasis and can also be used by cells to remove intracellular microbial pathogens. As such, some viruses such as herpes simplex virus-1 (HSV-1) have evolved mechanisms to suppress autophagy for their survival. In
David K. Ann +2 more
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Variants of hepatitis B virus [PDF]
Vox Sanguinis, 1992 Variations in the course of disease caused by hepatitis B virus may often be attributed to genomic variants of the virus. It must be kept in mind, however, that other factors, i.e. immunocompetence of the host and new methods of detection such as PCR, may also result in apparently aberrant phenotypic expression.
BONINO, FERRUCCIO +1 more
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Hepatitis B Virus: Advances in Prevention, Diagnosis, and Therapy
Clinical Microbiology Reviews, 2020 Currently, despite the use of a preventive vaccine for several decades as well as the use of effective and well-tolerated viral suppressive medications since 1998, approximately 250 million people remain infected with the virus that causes hepatitis B ...
M. Nguyen +4 more
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Hepatitis B virus persistence and reactivation
British medical journal, 2020 Hepatitis B virus (HBV) infection causes chronic hepatitis and has long term complications. Individuals ever infected with HBV are at risk of viral reactivation under certain circumstances.
Yu Shi, Min Zheng
semanticscholar +1 more source
Hepatitis B Virus Entry into Cells
Cells, 2020 Hepatitis B virus (HBV), an enveloped partially double-stranded DNA virus, is a widespread human pathogen responsible for more than 250 million chronic infections worldwide.
Charline Herrscher +2 more
semanticscholar +1 more source
eLife, 2012 Human hepatitis B virus (HBV) infection and HBV-related diseases remain a major public health problem. Individuals coinfected with its satellite hepatitis D virus (HDV) have more severe disease.
Huan Yan +19 more
semanticscholar +1 more source
Hepatitis B virus taxonomy and hepatitis B virus genotypes [PDF]
World Journal of Gastroenterology, 2007 Hepatitis B virus (HBV) is a member of the hepadnavirus family. Hepadnaviruses can be found in both mammals (orthohepadnaviruses) and birds (avihepadnaviruses). The genetic variability of HBV is very high. There are eight genotypes of HBV and three clades of HBV isolates from apes that appear to be additional genotypes of HBV.
openaire +3 more sources