Chronic hepatitis B virus (HBV) infection is a major health burden worldwide, with approximately 257 million people with chronic infection. HBV is a small partially double-stranded DNA virus that replicates within the nucleus of the hepatocyte and commonly leads to chronic infection.
April Wall, Ming V. Lin
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Autophagy by hepatitis B virus and for hepatitis B virus [PDF]
Autophagy is a catabolic process by which cells remove unwanted proteins and damaged organelles. It is important for maintaining cellular homeostasis and can also be used by cells to remove intracellular microbial pathogens. As such, some viruses such as herpes simplex virus-1 (HSV-1) have evolved mechanisms to suppress autophagy for their survival. In
David K. Ann+2 more
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Variants of hepatitis B virus [PDF]
Variations in the course of disease caused by hepatitis B virus may often be attributed to genomic variants of the virus. It must be kept in mind, however, that other factors, i.e. immunocompetence of the host and new methods of detection such as PCR, may also result in apparently aberrant phenotypic expression.
BONINO, FERRUCCIO+1 more
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A homosexual japanese man with acute hepatitis due to hepatitis B virus genotype ae, concurrent with amebic colitis [PDF]
We report herein a case with acute hepatitis due to hepatitis B virus genotype Ae, concurrent with amebic colitis. A 39-year-old homosexual Japanese man was admitted to our hospital with jaundice.
Ishikawa, Shin+9 more
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An appraisal of the prevention of mother-to-child transmission of hepatitis B virus health system in Nigeria [PDF]
The study aimed to assess the strengths and weaknesses, opportunities and threats influencing the achievement of prevention of mother-to-child transmission of hepatitis B virus.
Ebenso, B, Sodipo, OY
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Expression in Escherichia coli of a cloned DNA sequence encoding the pre-S2 region of hepatitis B virus [PDF]
A DNA sequence encoding the entire pre-S2 region (amino acids 120-174; serotype ayw) of human hepatitis B virus envelope protein has been inserted into the lacZ gene of the plasmid pSKS105 yielding a recombinant, pWS3.
Acs, George+7 more
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Human immunodeficiency virus and hepatitis C virus/hepatitis B virus co-infection in Southern Brazil: clinical and epidemiological evaluation [PDF]
Hepatitis B virus, hepatitis C virus and human immunodeficiency virus share a similar transmission pathway and are often diagnosed in the same patient. These patients tend to have a faster progression of hepatic fibrosis.
Beloto, Nayara Carvalho Polido+9 more
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Hepatitis B virus taxonomy and hepatitis B virus genotypes [PDF]
Hepatitis B virus (HBV) is a member of the hepadnavirus family. Hepadnaviruses can be found in both mammals (orthohepadnaviruses) and birds (avihepadnaviruses). The genetic variability of HBV is very high. There are eight genotypes of HBV and three clades of HBV isolates from apes that appear to be additional genotypes of HBV.
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Does limited virucidal activity of biocides include duck hepatitis B virucidal action? [PDF]
BACKGROUND: There is agreement that the infectivity assay with the duck hepatitis B virus (DHBV) is a suitable surrogate test to validate disinfectants for hepatitis B virucidal activity.
Bust, Uwe+5 more
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During hepatitis B virus (HBV) infection, selection and takeover of mutant viruses are frequent events driven by both humoral and cellular host-immune response and antiviral therapy. Therefore, dynamic studies of the variations of viral mutants over time within the overall viral population in relation with the host-virus interactions are extremely ...
BRUNETTO, MAURIZIA ROSSANA+2 more
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