Results 271 to 280 of about 13,643,530 (312)
Some of the next articles are maybe not open access.
Nature Reviews Gastroenterology & Hepatology, 2009
HBV replicates through reverse transcription of an RNA intermediate; the inherent lack of proofreading causes a high mutation frequency. Mutations in the precore and core promoter regions that abolish or reduce the production of hepatitis B e antigen occur most commonly.
Watcharasak, Chotiyaputta, Anna S F, Lok
openaire +2 more sources
HBV replicates through reverse transcription of an RNA intermediate; the inherent lack of proofreading causes a high mutation frequency. Mutations in the precore and core promoter regions that abolish or reduce the production of hepatitis B e antigen occur most commonly.
Watcharasak, Chotiyaputta, Anna S F, Lok
openaire +2 more sources
The hepatitis B virus polymerase
2021Hepatitis B virus (HBV) is a hepatotropic, partially double-stranded DNA virus that replicates by reverse transcription and is a major cause of chronic liver disease and hepatocellular carcinoma. Reverse transcription is catalyzed by the four-domain multifunctional HBV polymerase (P) protein that has protein-priming, RNA- and DNA-dependent DNA ...
Daniel N, Clark +3 more
openaire +2 more sources
Trends in Microbiology, 1993
Hepatitis B virus (HBV) is the causative agent of B-type hepatitis in humans and the prototypic member of the hepadnaviruses. It is a small enveloped DNA virus that replicates via reverse transcription. Although hepadnaviruses are similar to retroviruses in basic life cycle and genome organization, recent studies have revealed several unique ...
M, Nassal, H, Schaller
openaire +2 more sources
Hepatitis B virus (HBV) is the causative agent of B-type hepatitis in humans and the prototypic member of the hepadnaviruses. It is a small enveloped DNA virus that replicates via reverse transcription. Although hepadnaviruses are similar to retroviruses in basic life cycle and genome organization, recent studies have revealed several unique ...
M, Nassal, H, Schaller
openaire +2 more sources
The Lancet, 2009
Since the introduction of the hepatitis B vaccine and other preventive measures, the worldwide prevalence of hepatitis B infection has fallen. However, chronic infection remains a challenging global health problem, with more than 350 million people chronically infected and at risk of hepatic decompensation, cirrhosis, and hepatocellular carcinoma.
Yun-Fan, Liaw, Chia-Ming, Chu
openaire +2 more sources
Since the introduction of the hepatitis B vaccine and other preventive measures, the worldwide prevalence of hepatitis B infection has fallen. However, chronic infection remains a challenging global health problem, with more than 350 million people chronically infected and at risk of hepatic decompensation, cirrhosis, and hepatocellular carcinoma.
Yun-Fan, Liaw, Chia-Ming, Chu
openaire +2 more sources
The Nurse Practitioner, 1983
Hepatitis B is a major public health problem. Complications of the disease can include a carrier state, chronic active hepatitis, cirrhosis and hepatocellular carcinoma. The development of hepatitis B virus vaccine has made active immunization against HBV possible.
openaire +2 more sources
Hepatitis B is a major public health problem. Complications of the disease can include a carrier state, chronic active hepatitis, cirrhosis and hepatocellular carcinoma. The development of hepatitis B virus vaccine has made active immunization against HBV possible.
openaire +2 more sources
Myocarditis and Hepatitis B Virus
Angiology, 1985Two patients with hepatitis B virus infection and myocarditis are reported. The implicated pathogenesis was an immune complex mechanism in one pa tient. Both patients presented with heart failure and arrythmia which were con trolled with conventional medical therapy.
R K, Mahapatra, G H, Ellis
openaire +2 more sources
New England Journal of Medicine, 2008
More effective and less resistance-prone antiviral agents are now available to treat hepatitis B virus (HBV) infection. Profound, durable, therapeutic HBV DNA suppression to slow and reverse the progression of chronic HBV infection is important, given the evidence linking high-level HBV replication and the late consequences of chronic HBV infection ...
openaire +2 more sources
More effective and less resistance-prone antiviral agents are now available to treat hepatitis B virus (HBV) infection. Profound, durable, therapeutic HBV DNA suppression to slow and reverse the progression of chronic HBV infection is important, given the evidence linking high-level HBV replication and the late consequences of chronic HBV infection ...
openaire +2 more sources
Seminars in Fetal and Neonatal Medicine, 2007
Hepatitis B virus (HBV) infection is a worldwide health problem and may cause acute, fulminant, chronic hepatitis, liver cirrhosis, or hepatocelullar carcinoma (HCC). Infection with HBV in infancy or early childhood may lead to a high rate of persistent infection (25-90%), while the rates are lower if infection occurs during adulthood (5-10%).
openaire +2 more sources
Hepatitis B virus (HBV) infection is a worldwide health problem and may cause acute, fulminant, chronic hepatitis, liver cirrhosis, or hepatocelullar carcinoma (HCC). Infection with HBV in infancy or early childhood may lead to a high rate of persistent infection (25-90%), while the rates are lower if infection occurs during adulthood (5-10%).
openaire +2 more sources
Transmission of Hepatitis B Virus
Annals of Internal Medicine, 1982Excerpt To the editor: The article by Reiner and associates in the February issue (1) presents evidence to support de facto parenteral transmission as a source of hepatitis B virus (HBV) infections...
R M, Scott, W H, Bancroft, R, Snitbhan
openaire +2 more sources
Hepatitis B virus immunopathology
Springer Seminars in Immunopathology, 1995Approximately 5% of the world population is infected by the hepatitis B virus (HBV) which causes a necroinflammatory liver disease of variable duration and severity. Chronically infected patients with active liver disease carry a high risk of developing cirrhosis and hepatocellular carcinoma.
Chisari, F. V, FERRARI, Carlo
openaire +3 more sources