Results 71 to 80 of about 14,611,152 (262)

Healthcare related factors associated with mono-infection and co-infection of bloodborne viruses in Lasbela and Quetta, Baluchistan

Journal of the Pakistan Medical Association
Objective: To determine the frequency of human immunodeficiency virus, hepatitis B virus and hepatitis C virus infection, and to compare the prevalence and risk factors of mono-infection versus co-infection.
Nida Rasheed, Mehtab Karim , Syeda Tabeena Ali   +2 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Tracking the source of the hepatitis B virus-specific CD8 T cells during lamivudine treatment [PDF]

, 2003
Lamivudine treatment in chronic hepatitis B leads to the reconstitution of virus-specific T cells in the circulation, but it is not clear whether this is the preferential result of T cell efflux from the liver or lymph nodes.
Gotto, J, Williams, R, Webster, GJM, Dusheiko, GM, Bertoletti, A, Malacarne, F, Reignat, S, Behboudi, S, Burroughs, AK   +8 more
core  

Hepatitis B and C co-Infection are independent predictors of progressive kidney disease in HIV-positive, antiretroviral-treated adults [PDF]

, 2012
Chronic kidney disease (CKD) is an important cause of morbidity and mortality in HIV-positive individuals. Hepatitis C (HCV) co-infection has been associated with increased risk of CKD, but prior studies lack information on potential mechanisms.
Bickel, M, ESPRIT Study Group, Amanda Mocroft, Christina M Wyatt, Ross, Michael J., Aleksandra Szymczak, ESPRIT Study Group, Daniel Grint, Jens Lundgren, Ryom, Lene, Lene Ryom, Neuhaus, Jacqueline, Bickel, Markus, Szymczak, A, Peters, L, Jacqueline Neuhaus, Ross, MJ, Michael J Ross, Koirala, J, Neuhaus, J, Szymczak, Aleksandra, Mocroft, Amanda, Peters, Lars, Grint, D, Markus Bickel, Grint, Daniel, Wyatt, CM, Janak Koirala, INSIGHT SMART Study Group, Lundgren, Jens, Ross, Michael J, Koirala, Janak, Ryom, L, Mocroft, A, Lars Peters, Lundgren, J, Wyatt, Christina M, Wyatt, Christina M.   +37 more
core   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Adverse Pregnancy Outcomes and Prognostic Factors in Hepatitis B Virus Patients with Intrahepatic Cholestasis During Pregnancy

Clinical and Experimental Obstetrics & Gynecology
Background: We conducted this study to investigate adverse pregnancy outcomes of hepatitis B virus infection coexistng with intrahepatic cholestasis in pregnant women, along with identifying associated risk factors.
Chong Zhang, Hong Wei, Zhiqiang Zhao, Yunxia Zhu   +3 more
doaj   +1 more source

Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. [PDF]

, 2012
The S-type lectin galectin-9 binds to the negative regulatory molecule Tim-3 on T cells and induces their apoptotic deletion or functional inactivation.
Cheng, Y, Richard Gilson, Singh, HD, Nebbia Gaia, Dusheiko, G., William Rosenberg, Peppa, D, Cheng, Y., Geoffrey Dusheiko, Cheng Yang, Joanne ChinAleong, ChinAleong, J, Patrick Kennedy, Dusheiko Geoffrey, Maini Mala K., Singh Harsimran D., Pooja Khanna, Maini, MK, Nebbia, G., Khanna, P, Gaia Nebbia (125377), Rosenberg, W, Rosenberg William, Rosenberg, W., Schurich, Anna; id_orcid, Gilson, R, ChinAleong Joanne, Mala K. Maini (125417), Patrick Kennedy (125414), Mala K Maini, Harsimran D Singh, Gilson Richard, ChinAleong, J., Gaia Nebbia, Harsimran D. Singh (125388), Nebbia, G, Khanna Pooja, Kennedy, P., Richard Gilson (125405), Schurich, A, Anna Schurich, Joanne ChinAleong (125409), Geoffrey Dusheiko (125400), Kennedy, P, Singh, H.D., Pooja Khanna (125385), William Rosenberg (14858), Khanna, P., Peppa Dimitra, Gilson, R., Kennedy Patrick, Yang Cheng (125394), Dusheiko, G, Dimitra Peppa, Dimitra Peppa (125379), Yang Cheng, Anna Schurich (125382), Maini, M.K., Peppa, D., Schurich Anna   +59 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Comprehensive Identification of Bridge Genes to Explain the Progression from Chronic Hepatitis B Virus Infection to Hepatocellular Carcinoma

Journal of Inflammation Research, 2021
Wenwei Nong,1,* Liping Ma,2,* Biyang Lan,1 Ning Liu,1 Hongzhi Yang,1 Xiaoxia Lao,2 Qiaomei Deng,2 Zhihu Huang2 1Department of General Surgery, Affiliated Minzu Hospital of Guangxi Medical University, Nanning, People’s Republic of China; 2Department
Nong W, Ma L, Lan B, Liu N, Yang H, Lao X, Deng Q, Huang Z   +7 more
doaj