Results 81 to 90 of about 458,398 (305)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Human immunodeficiency virus and hepatitis C virus/hepatitis B virus co-infection in Southern Brazil: clinical and epidemiological evaluation

Brazilian Journal of Infectious Diseases, 2014
Hepatitis B virus, hepatitis C virus and human immunodeficiency virus share a similar transmission pathway and are often diagnosed in the same patient. These patients tend to have a faster progression of hepatic fibrosis.
Sonia Mara Raboni, Felipe Francisco Tuon, Nayara Carvalho Polido Beloto, Henrique Demeneck, Andre Oliveira, Denis Largura, Andressa Gervasoni Sagrado, Bárbara Perdonsini Lima, João Paulo Franzoni, Maria Lucia Pedroso   +9 more
doaj   +1 more source

Frequency of hepatitis D virus infection in individuals with hepatitis B surface antigen-positive (HBS Ag) in Ardabil province [PDF]

Frequency of hepatitis D virus infection in individuals with hepatitis B surface antigen-positive (HBS Ag) in Ardabil province Introduction: hepatitis D virus (HDV) and hepatitis B virus (HBV)co-infection is well known to induce a spectrum of acute ...
امانی, فیروز, شاکر, سمیه, هوشيار, افشين   +2 more
core  

Requirement of Activation for Hepatitis B Virus Infection [PDF]

, 2007
Although _in vitro_ models of human hepatitis B virus replication are established, so far none could approximate infection efficiency as expected from _in vivo_ observations.
Claudia Maenz, Michael Bruns
core   +1 more source

Impact of previous hepatitis B infection on the clinical outcomes from chronic hepatitis C? A population-level analysis [PDF]

, 2018
Chronic coinfection with hepatitis C virus (HCV) and hepatitis B virus (HBV) is associated with adverse liver outcomes. The clinical impact of previous HBV infection on liver disease in HCV infection is unknown. We aimed at determining any association of
Allen, S., Barclay, S. T., Bhattacharyya, D., Dillon, J. F., Fox, R., Fraser, A., Gunson, R., Hayes, P. C., Hunt, A., Hutchinson, S. J., Innes, H. A., Kennedy, N., Mcintrye, P. G., Mills, P. R., Morris, J., Stanley, A. J., Swann, R., Thomas, E., Valerio, H., Wang, H., Wilks, D.   +20 more
core   +4 more sources

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

Healthcare related factors associated with mono-infection and co-infection of bloodborne viruses in Lasbela and Quetta, Baluchistan

Journal of the Pakistan Medical Association
Objective: To determine the frequency of human immunodeficiency virus, hepatitis B virus and hepatitis C virus infection, and to compare the prevalence and risk factors of mono-infection versus co-infection.
Nida Rasheed, Mehtab Karim , Syeda Tabeena Ali   +2 more
doaj   +1 more source

Future prevention and treatment of chronic hepatitis B infection [PDF]

, 2012
Vaccination for hepatitis B virus (HBV) infection and treatment for chronic hepatitis B, while effective for primary prevention and control of the disease, still have their limitations. Global coverage of HBV immunization needs improvement.
Fung, J, Lai, CL, Seto, WK, Yuen, MF
core   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source