Results 91 to 100 of about 316,128 (311)

Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life : an international, multicenter, randomized, controlled study [PDF]

, 2012
Background: Hepatitis C decreases health related quality of life (HRQL) which is further diminished by antiviral therapy. HRQL improves after successful treatment.
Neumann, Avidan U, Hansen, B.E. (Bettina), Esteban, Juan I, Zeuzem, S, Verheij-Hart, E. (Elke), Neumann, A.U. (Avidan), de Knegt, Robert J., Gool, A.R. (Arthur) van, Hansen, Bettina E, Lurie, Y, Lagging, M. (Martin), Schalm, Solko Walle, Esteban, Juan I., Lurie, Y. (Yoav), Hansen, Bettina, Negro, F, Hansen, Bettina E., Verheij-Hart, E, de Knegt, Robert J, Lagging, Martin,, Pawlotsky, Jean Michel, Lagging, Martin, Hansen Bettina E, Pawlotsky, Jean-Michel, Negro, F. (Francesco), Ferrari, C. (Carlo), Neumann, AU (Avidan), Schalm, Solko W., Gool, AR, Bezemer, G. (Geert), van Gool, Arthur R., Lurie, Yoav, Negro Francesco, Ferrari, C, Schalm Solko W, Knegt, R.J. (Robert) de, Lagging, M, de Knegt, Rob, Zeuzem Stefan, Verheij-Hart Elke, Schalm, S.W. (Solko), Verheij-Hart, Elke, Bezemer Geert, Lagging Martin, Pawlotsky Jean-Michel, Ferrari Carlo, Neumann Avidan U, de Knegt Robert J, Schalm, Solko W, Esteban Juan I, Esteban, JI, Verheij Hart, Elke, Negro, Francesco, Lurie Yoav, Schalm, Solko, Neumann, Avidan U., Knegt, Robert Jacobus de, Pawlotsky, JM, Van Gool Arthur R, Pawlotsky, J-M. (Jean-Michel), Zeuzem, S. (Stefan), Ferrari, Carlo, Bezemer, Geert, Van Gool, Arthur R, Esteban, J.I. (Juan), Zeuzem, Stefan   +65 more
core   +1 more source

COVID-19 Mid-term Impact on Hepatocellular Carcinoma in Patients With Hepatitis C Chronic Infection. [PDF]

In Vivo, 2021
Guler-Margaritis S, Mercan-Stanciu A, Toma L, Rusie D, Isac T, Dodot M, Zgura A, Bacalbasa N, Haineala B, Badiu DC, Serban D, Iliescu EL.   +11 more
europepmc   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source

Viral hepatitis

South African Family Practice, 2006
The hepatitis A, B, C, D and E viruses primarily target the liver to cause viral hepatitis. Hepatitis A (HAV) and E (HEV) viruses are transmitted by the faecal-oral route and cause acute viral hepatitis.
D. Brink
doaj   +1 more source

Eradicating chronic Hepatitis C Viraemia : lessons learnt during the last decade [PDF]

, 2005
Over the last decade a better understanding of the mechanism for immune disposal of hepatocytes infected with the Hepatitis C virus enabled the design of antiviral regimens with increasing efficacy.
Pullicino, Edgar
core  

Factors associated with testing for hepatitis C in an internet-recruited sample of men who have sex with men.

, 2001
BACKGROUND: Nearly 4 million individuals in the United States (1.8%) have been infected with hepatitis C virus, yet few are aware of their infection. GOAL: To identify correlates associated with hepatitis C virus testing among a sample of men who have ...
Diclemente, RJ, Hergenrather, KC, Rhodes, SD, Yee, LJ   +3 more
core   +1 more source

Antiviral treatment alters the frequency of activating and inhibitory receptor-expressing natural killer cells in chronic Hepatitis B virus infected patients [PDF]

, 2012
Natural killer (NK) cells play a critical role in innate antiviral immunity, but little is known about the impact of antiviral therapy on the frequency of NK cell subsets.
Xiumei Chi, Lv, J., Yu Pan, Zhigang Tian, Niu, J., Juan Lv, Weihua Xiao, Yan, H., Xu, D., Zhengkun Tu, Hu, X., Chi, X., Junqi Niu, Qinglong Jin, Xiao, W., Sun, H., Hou, J., Jinlin Hou, Hongqing Yan, Haibo Sun, Tian, Z., Tu, Z., Xiaoli Hu, Jin, Q., Pan, Y., Damo Xu   +25 more
core   +1 more source

Prevalence and Pattern of Resistance in NS5A/NS5B in Hepatitis C Chronic Patients Genotype 3 Examined at a Public Health Laboratory in the State of São Paulo, Brazil. [PDF]

Infect Drug Resist, 2021
de Torres Santos AP, Martins Silva VC, Mendes-Corrêa MC, Lemos MF, de Mello Malta F, Santana RAF, Dastoli GTF, de Castro VFD, Pinho JRR, Moreira RC.   +9 more
europepmc   +1 more source

ProSiteHunter: A Unified Framework for Sequence‐Based Prediction of Protein‐Nucleic Acid and Protein‐Protein Binding Sites

Advanced Science, EarlyView.
This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou, Qihang Zhen, Zexin Lv, Xinyue Cui, Suhui Wang, Minghua Hou, Zhan Zhou, Xiaogen Zhou, Guijun Zhang   +8 more
wiley   +1 more source

Relation of IL28B gene polymorphism with biochemical and histological features in hepatitis C virus-induced liver disease.

PLoS ONE, 2012
Background/aimsPolymorphism at the IL28B gene may modify the course of hepatitis C virus (HCV) chronic infection. Our aim was to study the influence of IL28B rs12979860 gene polymorphism on the biochemistry and pathology of HCV-induced disease in the ...
José A Agúndez, Elena García-Martin, María L Maestro, Francisca Cuenca, Carmen Martínez, Luis Ortega, Miguel Carballo, Marta Vidaurreta, Marta Agreda, Gabriela Díaz-Zelaya, Avelina Suárez, Manuel Díaz-Rubio, José M Ladero   +12 more
doaj   +1 more source