Results 71 to 80 of about 298,000 (263)

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Hepatitis B and Hepatitis C Co-infection: Treatment Approaches and A Case Report

Viral Hepatitis Journal
Hepatitis B virus (HBV) and hepatitis C virus (HCV) co-infection is a significant health issue worldwide and can accelerate liver damage when they occur together.
Mirkan Bulğak, Tuna Demirdal
doaj   +1 more source

Relation of IL28B gene polymorphism with biochemical and histological features in hepatitis C virus-induced liver disease.

PLoS ONE, 2012
Background/aimsPolymorphism at the IL28B gene may modify the course of hepatitis C virus (HCV) chronic infection. Our aim was to study the influence of IL28B rs12979860 gene polymorphism on the biochemistry and pathology of HCV-induced disease in the ...
José A Agúndez, Elena García-Martin, María L Maestro, Francisca Cuenca, Carmen Martínez, Luis Ortega, Miguel Carballo, Marta Vidaurreta, Marta Agreda, Gabriela Díaz-Zelaya, Avelina Suárez, Manuel Díaz-Rubio, José M Ladero   +12 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

CHRONIC HEPATITIS C

The Professional Medical Journal, 2010
Objectives: To know efficacy of combination of standard interferon α2b and ribavirin in chronic hepatitis C. Design: Prospective and analytical. Setting: CMH Bahawalpur. Period: Nov 2008 to Dec 2009. Materials and methods: A total of 126 patients, 104 males and 22 females, fulfilling inclusion and exclusion criteria were started combination treatment ...
SHAUKAT ALI, SYED KHURRAM SHAHZAD, ATIQ UR REHMAN SLEHRIA   +2 more
openaire   +2 more sources

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

Advanced Science, EarlyView.
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu, Jun Yang, Yuhang Zhang, Xiaoli Xue   +3 more
wiley   +1 more source

Development of hepatocellular carcinoma in a patient with chronic hepatitis C and cirrhosis. Сlinical case

Лечащий Врач
Background. Chronic hepatitis C is currently an urgent problem worldwide. According to the World Health Organization, there are currently more than 50 million people living with chronic hepatitis C virus infection, with approximately 1 million new cases ...
I. V. Mannanova, M. A. Kiryakova, Zh. B. Ponezheva, V. V. Makashova, N. A. Antipyat, O. A. Ivanova, V. Lusenina   +6 more
doaj   +1 more source

Clinical-epidemiological and pathogenetic features of viral hepatitis C in the hemodialysis departments

Трансплантология (Москва), 2019
Background. Today, the programmed hemodialysis belongs to the clinical medicine area where patients are at a constant risk of viral hepatitis infection. This is associated with surgical interventions on the vessels, fairly frequent transfusions of blood ...
R. N. Akalaev, G. Z. Aripkhodzhaeva, S. A. Rashidova, A. N. Abdullaev, K. A. Khashimov   +4 more
doaj   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

Advanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun, Junhao Fan, Xiaolu Xie, Yuting Shi, Xiaoqing Liu, Tiefeng Xu, Sidi Yang, Keda Shi, Chengshu Xie, Shixiong Li, Siwen Chen, Ruoxi Cai, Ping He, Yuzhen Ye, Tao Chen, Xiancai Ma, Chunmei Li, Jingyou Yu, Deyin Guo   +18 more
wiley   +1 more source

КЛИНИКО-ЛАБОРАТОРНАЯ ХАРАКТЕРИСТИКА ХРОНИЧЕСКИХ ГЕПАТИТОВ И ЦИРРОЗОВ ПЕЧЕНИ РАЗЛИЧНОЙ ЭТИОЛОГИИ

Архивъ внутренней медицины, 2015
The review of literature discusses the clinical and biochemical changes in patients with chronic hepatitis C, chronic hepatitis of alcoholic etiology, chronic hepatitis combined genesis (HCV + alcohol) and cirrhosis in the outcome of hepatitis, liver ...
А. Р. Билалова, В. В. Макашова   +1 more
doaj   +1 more source