Meta-analysis of functional genomics studies reveals conserved cellular pathways required by viruses of pandemic concern. [PDF]
Brice AM, Caputo AT, Stewart CR.
europepmc +1 more source
ABSTRACT Background: Post‐transplant diabetes mellitus (PTDM) is a common complication following liver transplant (LT) and is associated with adverse outcomes. The triacylglycerol‐glucose product (TyG) and the triacylglycerol‐to‐high‐density lipoprotein (HDL) cholesterol ratio (TAG/HDL‐c) are indices that can serve as triacylglycerol‐based proxies for ...
Mateo Chvatal‐Medina +9 more
wiley +1 more source
Four methods for estimating hepatitis C incidence using extant testing data. [PDF]
McFarlane WJ +3 more
europepmc +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Transient receptor potential channels in <i>Flaviviridae</i> infection: A comprehensive review. [PDF]
Jiang F, Yao X, Zheng CB.
europepmc +1 more source
SARS‐CoV‐2 enhances lysosomal exocytosis and deacidifies lysosomes to facilitate viral release
Abstract The mechanism of SARS‐CoV‐2 egress predominantly governs the quantity and quality of progeny viruses, thereby significantly contributing to viral pathogenicity. However, the key factors influencing viral egress remain largely unclear. In this study, using transcription‐ and replication‐competent SARS‐CoV‐2 virus‐like‐particle (SARS‐CoV‐2 trVLP)
Fujun Qin +7 more
wiley +1 more source
Potential reasons for the decline of new HIV cases among people who inject drugs (PWID) in Kyrgyzstan. [PDF]
Moldokmatova A +7 more
europepmc +1 more source
Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao +4 more
wiley +1 more source
HEV prevalence, risk factors and outcomes in a tertiary care hospital of Uttar Pradesh: a retrospective observational study. [PDF]
Hassaan S +7 more
europepmc +1 more source

