Results 221 to 230 of about 159,244 (259)

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux   +6 more
wiley   +1 more source

On an Aggregation Theory for Indicators Expressing Behaviors of Complex Systems With an Application to Sustainability

open access: yesSustainable Development, EarlyView.
ABSTRACT Certain attributes of large‐scale complex systems are often expressed through sets of indicators. For example, the sustainability of an entity, be it a nation, a city, an energy system, a corporation etc., can be effectively represented by indicators and corresponding data series.
Vassilis S. Kouikoglou   +1 more
wiley   +1 more source

Nanoparticle approaches for hepatitis therapy and clinical translation. [PDF]

open access: yesDiscov Nano
Mohamed NA   +9 more
europepmc   +1 more source

Iowa Population Exposures to Metals and Metalloids in Well Water

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Previous Iowa studies suggest low levels and chronic arsenic exposures are associated with prostate cancer. The rural Iowa population heavily relies on private wells for drinking water resources and thus is vulnerable to contaminants such as heavy metals found in well water.
Donald L. Simmons   +9 more
wiley   +1 more source

CRISPR/Cas9 Genome Engineering in Non‐Conventional Oleaginous Yeasts: Applications, Challenges, and Prospects

open access: yesYeast, EarlyView.
ABSTRACT Given the biotechnological potential of yeast‐derived oils for oleochemical production, genes encoding lipid metabolism enzymes are key targets for metabolic engineering. Genetic engineering tools such as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9, Transcription Activator‐Like Effector Nucleases (TALENs), Zinc ...
Rodrigo Gonçalves Dias   +5 more
wiley   +1 more source

Inhibition of Targeted Bacterial Growth Using MazF‐Expressing Phagemids: A Novel Therapeutic Approach Based on Endoribonuclease Toxin Molecules

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT The extensive and indiscriminate use of antibiotics, which are intended to halt bacterial growth or eliminate them, has unintentionally given rise to antimicrobial resistance (AMR), which is a critical threat to global health. In the pursuit of alternative solutions, researchers have focused on type II toxin–antitoxin systems prevalent within ...
Hana Hasegawa   +6 more
wiley   +1 more source

The prognosis characteristics of HIV/HBV co-infection after antiviral therapy: a comprehensive review. [PDF]

open access: yesInfect Agent Cancer
Peng A   +10 more
europepmc   +1 more source

Prenatal Prescription Opioid Analgesic Exposure and Academic Performance in Third Grade Children: A Population‐Based Cohort Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the association between prenatal exposure to opioids analgesics and academic performance in third grade children. Design Population‐based cohort study using linked data from New South Wales birth records, medicine dispensing data, and national standardised test results.
Bianca Varney   +7 more
wiley   +1 more source

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