Results 141 to 150 of about 958,101 (344)

GSK461364 Inhibits NLRP3 Inflammasome by Targeting NEK7 Phosphorylation

Advanced Science, EarlyView.
Schematic diagram of the mechanism by which GSK461364 inhibits NLRP3 inflammasome activation. GSK461364 inhibits the phosphorylation of NEK7 likely at serine 221 and serine 260 by suppressing the activity of PLK1, thereby restraining the formation of the NLRP3 inflammasome.
Ruiheng Luo, Mingliang Ma, Dan Wang, Ling Luo, Xueming Xu, Lingmin Huang, Fupeng Wang, Guangyan Kuang, Huiqi Liu, Rui Ni, Xin Li, Qinghua Zhang, Shengfeng Wang, Kai Zhao   +13 more
wiley   +1 more source

The duck hepatitis B virus core protein contains a highly phosphorylated C terminus that is essential for replication but not for RNA packaging [PDF]

, 1989
H J Schlicht, Ralf Bartenschlager, Heinz Schaller   +2 more
openalex   +1 more source

Hepatitis B, hepatitis C and HIV in Irish prisoners, part II: prevalence and risk in committal prisoners 1999. [PDF]

, 2000
The results of a census survey of 1205 Irish prisoners, published in August 1999, showed that the prevalence of infection with hepatitis B was 9%, the prevalence of infection with hepatitis C was 37%, and the prevalence of infection with HIV was 2%.
Allwright, Shane, Barry, Joseph, Bradley, Fiona, Long, Jean, Reaper-Reynolds, Sheilagh, Thornton, Lelia   +5 more
core  

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

Advanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng, Zheyan Fang, Shuang Zhao, You‐en Zhang, Na Wu, Zhenyang Guo, Xin Zhong, Bixuan Jiang, Hongfei Xu, Hangnan Hong, Zhentao Zhang, Mukaddas Abdurahman, Xueting Yu, Jilong Geng, Xiansu Nie, Supuya Abuduwahapi, Dong Huang, Gang Zhao, Wenbin Zhang, Hao Lu, Li Shen, Xin Zhao, Zhaoyang Chen, Junjie Guo, Hongchao Zheng, Yue He, Sanwu Wu, Jiayin Peng, Jiawen Song, Xiao Wang, Haomin Li, Yuli Huang, Shengying Qin, Haojie Lu, Xiangdong Wang, Jianguo Zhao, Lei Huang, Yun Zhao, Peng Li, Junbo Ge, Hua Li   +40 more
wiley   +1 more source

Transmission of Hepatitis C Virus from Mothers to Infants [PDF]

, 1994
Hitoshi Ohto, Sousuke Terazawa, Nobuhiko Sasaki, Nobutaka Sasaki, Kunihiko Hino, Chieko Ishiwata, Makoto Kako, Niro Ujiie, Chikara Endo, Akira Matsui, Hiroaki Okamoto, Shunji Mishiro   +11 more
openalex   +1 more source

Resident Macrophage‐Orchestrated Immune and Fibroblast Interactions in Immune Checkpoint Inhibitor‐Associated Nephrotoxicity

Advanced Science, EarlyView.
Schematic illustration of resident macrophages in Immune checkpoint inhibitor‐associated nephrotoxicity (ICI‐AN). Using an integrated approach (including imaging mass cytometry, transcriptomics, and murine models), this study reveals that resident macrophages drive immune‐stromal interactions in ICI‐AN, promoting fibroblast activation through CXCL9 and
Yanhong Ma, Yang Chen, Qinfan Yao, Yuxi Wang, Nan Ouyang, Fei Han, Guzong Wang, Meifang Wang, Yuan Yuan, Jianghua Chen, Jianzhen Shan, Dajin Chen   +11 more
wiley   +1 more source

GSDMD induces hepatocyte pyroptosis to trigger alcoholic hepatitis through modulating mitochondrial dysfunction

Cell Division
Background Mechanisms and consequences of Gasdermin D (GSDMD) activation in alcoholic hepatitis (AH) are unclear. In the present study, we investigated whether GSDMD induces hepatocyte pyroptosis by regulating mitochondrial dysfunction in AH.
Yandi Xie, Zilong Wang, Guangjun Song, Hui Ma, Bo Feng   +4 more
doaj   +1 more source

Long-Term Real-World Outcomes of Tenofovir Alafenamide in Chronic Hepatitis B: Detailed Analysis of Treatment-Naive and Experienced Patients

The Korean Journal of Gastroenterology
Background/Aims: This study assessed the long-term efficacy and safety of tenofovir alafenamide (TAF) in real-world settings. Methods: Patients who were candidates for TAF treatment and were followed up at 12-week intervals over 192 weeks were enrolled ...
Yu-Xuan Song, Guang-Jun Song, Hui Ma, Bo Feng, Yan-Di Xie   +4 more
doaj   +1 more source

Prediction of the response of chronic hepatitis C to interferon alfa: a statistical analysis of pretreatment variables. [PDF]

, 1993
J. Camps, S Crisóstomo, Marta Garcı́a-Granero, José Ignacio Riezu‐Boj, M.P. Civeira, Jesús Prìeto   +5 more
openalex   +1 more source

Practices of Nurse Practitioners in Screening for Hepatitis C [PDF]

, 2015
Presented to the Faculty of the University of Alaska Anchorage in Partial Fulfillment of the Requirements for the Degree of MASTER OF SCIENCEThe purpose of this project was to determine both hepatitis C virus (HCV) screening rates and the percentage ...
Thompson, Jordin A.
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