Results 171 to 180 of about 958,101 (344)

At least five related, but distinct, hepatitis C viral genotypes exist. [PDF]

, 1992
T A, Eileen L. Beall, Bruce Irvine, Janice A. Kolberg, David Chien, George Kuo, M. S. Urdea   +6 more
openalex   +1 more source

Alternative Models for Anticancer Drug Discovery From Natural Products Using Binary Tumor‐Microenvironment‐on‐a‐Chip

Advanced Science, EarlyView.
This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim, Si Hyeon Chae, Dahae Lee, Bum Soo Lee, Jiseok Lim, Hyo‐Il Jung, Ki Hyun Kim, Bongseop Kwak   +7 more
wiley   +1 more source

Degree of Viremia and Liver Histology in Chronic Hepatitis C

, 1970
Md Atiqur Rahman, Sultana Rokeya Mannan
openalex   +2 more sources

Status of Health related Quality of life between HBV and HCV Patients of Pakistan [PDF]

The aim of the study is to explore the factors those differentiate health related quality of life (HRQOL) among hepatitis B (HBV) and hepatitis C (HCV) patients. Different public and private hospitals of Sargodha district were visited and 120 patients of
Ali, Mumtaz, Aslam, Muhammad Amir, Awan, Masood Sarwar, Waqas, Muhammad   +3 more
core   +1 more source

Discovery of a Baloxavir‐Inspired Endonuclease Inhibitor That Prevents Herpes Simplex Virus 1 Replication in Cell Culture and In Vivo

Advanced Science, EarlyView.
Current herpesvirus treatments targeting the viral DNA polymerase are limited by toxicities and drug resistance. Novel compounds inhibiting the nuclease activity of the herpes simplex virus 1 (HSV‐1) terminase complex, required for viral genome packaging, have been identified.
Sabina Andreu, Kai Tang, Jiahui Zhou, Gabriel Pino‐Peco, Nerea López‐Carrobles, Raquel Bello‐Morales, Daniel Galdo‐Torres, Lina Zhang, Federico Gago, José Antonio López‐Guerrero, Xinyong Liu, Peng Zhan, Luis Menéndez‐Arias   +12 more
wiley   +1 more source

Clathrin Light Chain B Drives Hepatocellular Carcinoma Progression Through Dual Mechanisms: Small Extracellular Vesicle‐Mediated Angiogenesis and the NF‐κB–PCLAF Signaling Axis

Advanced Science, EarlyView.
Clathrin Light Chain B (CLTB) drives hepatocellular carcinoma progression through dual pathways: intracellularly, it activates the NF‐κB–PCLAF axis to enhance small extracellular vesicle (sEV) uptake and tumor proliferation; extracellularly, CLTB‐enriched sEVs bind SH3KBP1 to inhibit its degradation, inducing angiogenesis and vascular leakage ...
Xiaoke Sun, Junchen Guo, Ning Zhao, Guanghua Cui, Yun Bai, Meijuan Ding, Yi Xu, Yu Yang   +7 more
wiley   +1 more source

METABOLISM OF THE BLOOD INSULIN AND C-PEPTIDE IN ACUTE HEPATITIS

, 1984
Shinobu Tanabashi, Shoko IWAI, Takashi Tsuji, Yasuhiko KAWADE, Tatsuo Wakahara, Shigeki Yamada, Hiroshi Kajinuma   +6 more
openalex   +2 more sources

Interferon alfa for chronic hepatitis C in haemophiliacs. [PDF]

, 1993
Michael Makris, F E Preston, D. R. Triger, J. C. E. Underwood, L Westlake, MI Adelman   +5 more
openalex   +1 more source

Hepatitis C and autoimmune hepatitis [PDF]

Hepatology, 2000
openaire   +3 more sources

AI‐Assisted Drug Re‐Purposing for Human Liver Fibrosis

Advanced Science, EarlyView.
A multi‐agent AI (AI co‐scientist) is used to repurpose drugs for liver fibrosis treatment and to guide their experimental characterization. The anti‐fibrotic efficacy and toxicity of these drugs is assessed in multi‐lineage human hepatic organoids grown in microwells (microHOs).
Yuan Guan, Lu Cui, Jakkapong Inchai, Zhuoqing Fang, Jacky Law, Alberto Alonzo Garcia Brito, Annalisa Pawlosky, Juraj Gottweis, Alexander Daryin, Artiom Myaskovsky, Lakshmi Ramakrishnan, Anil Palepu, Kavita Kulkarni, Wei‐Hung Weng, Zhuanfen Cheng, Vivek Natarajan, Alan Karthikesalingam, Keran Rong, Yunhan Xu, Tao Tu, Gary Peltz   +20 more
wiley   +1 more source