Results 181 to 190 of about 20,261,647 (304)

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

open access: yesHepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai   +29 more
wiley   +1 more source

Rheumatology Informatics System for Effectiveness Registry Participation Associated With Significant Gains in Quality Measure Performance: An Interrupted Time Series Analysis

open access: yesArthritis &Rheumatology, EarlyView.
Objective To examine the association between participation in a qualified clinical data registry and quality measure performance. Methods We included practices that joined the American College of Rheumatology's Rheumatology Informatics System for Effectiveness (RISE) registry between 2015 and 2021.
Gabriela Schmajuk   +5 more
wiley   +1 more source

Outcomes After 4-Week Course of Sofosbuvir/Velpatasvir Therapy in Hepatitis C Seronegative Recipients of Kidneys From Hepatitis C Viremic Deceased Donors. [PDF]

open access: yesClin Transplant
Kummangal BA   +10 more
europepmc   +1 more source

Hepatitis C testing : infographic

open access: yes
Hepatitis C causes serious liver disease, even liver cancer. Blood tests are needed to tell if you have hepatitis C. A screening blood test, called an antibody test, shows if a person has ever been infected with the hepatitis C virus.

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Valorization of bark extracts from Cerrado and Amazon species: phenolic characterization, antioxidant capacity, and photoprotective potential for circular bioeconomy applications

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Tree bark remains an underexploited source of high‐value‐added phenolic compounds with potential circular bioeconomy applications. This work characterized bark extracts from two species of distinct Brazilian biomes, Stryphnodendron adstringens (Cerrado) and Myrcia eximia (Amazon), obtained with three solvents (ethanol, methanol and acetone ...
Mário Sérgio Lorenço   +7 more
wiley   +1 more source

Hepatitis C and injection drug use

open access: yes
Hepatitis C is a serious liver disease caused by the Hepatitis C virus. About 80% of people who get infected develop a chronic, or lifelong, infection. Over time, chronic Hepatitis C can cause serious health problems including liver damage, liver failure,

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Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun   +4 more
wiley   +1 more source

Evaluating a virtual paediatric adverse drug reaction clinic

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Adverse drug reactions (ADRs) are a common problem in paediatric health care. There is limited access to expertise in the evaluation and management of potential ADRs in children, limiting access to these services and creating delays in assessment and management.
Emily Hauck   +2 more
wiley   +1 more source

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