Results 191 to 200 of about 20,131,715 (394)

Inhibition of Hepatitis C Virus Replicon RNA Synthesis by PSI-352938, a Cyclic Phosphate Prodrug of β-d-2′-Deoxy-2′-α-Fluoro-2′-β-C-Methylguanosine

, 2011
Angela M. Lam, Christine Espiritu, Eisuke Murakami, Véronique Zennou, Shalini Bansal, Holly M. Micolochick Steuer, Congrong Niu, Meg Keilman, Haiying Bao, Nigel Bourne, Ronald L. Veselenak, P. Ganapati Reddy, Wonsuk Chang, Jinfa Du, Dhanapalan Nagarathnam, Michael J. Sofia, Michaël Otto, Phillip A. Furman   +17 more
openalex   +2 more sources

Unexpectedly High Incidence of Immune‐Related Adverse Events in Gastric Cancer Patients Who Received Conversion Surgery After Nivolumab‐Including Chemotherapy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Nivolumab‐including chemotherapy (nivo‐CTX) for stage IV gastric cancer (GC) may increase the chance of conversion surgery but risk of immune‐related adverse events (irAEs) during perioperative period remains unclear. Methods We examined irAEs in 36 patients with marginally resectable GC who received nivo‐CTX followed by surgery ...
Masashi Nishino, Takaki Yoshikawa, Hirokazu Shoji, Yuki Takenaka, Maho Takuwa, Yurina Fujisaki, Rei Ogawa, Takeyuki Wada, Tsutomu Hayashi, Yukinori Yamagata, Nobuyoshi Hiraoka, Yasuyuki Seto   +11 more
wiley   +1 more source

Enantioconvergent Access to Chiral S(VI) Stereocenters by Kinetic Resolution of Sulfonimidoyl Chlorides

Angewandte Chemie, EarlyView.
An enantioconvergent approach for the kinetic resolution of S(VI) stereocenters that leverages the electrophilic reactivity of the chiral sulfur atom is described. The catalytic process provides access to sulfonimidoyl chlorides and sulfonimidates, which are among the least studied S(VI) functionalities.
Arko Das, Shree Krishna Dhakal, Ramon Trevino, Seth O. Fremin, Vy T. B. Nguyen, Arka Porey, Sachchida Nand, Chandan Kumar Giri, Daniel J. Wherritt, Hadi D. Arman, Oleg V. Larionov   +10 more
wiley   +2 more sources

Predictors of linkage to care for a nontargeted emergency department hepatitis C screening program

, 2019
Joshua Blackwell, Joel B. Rodgers, Ricardo Franco, Stacey S. Cofield, Lauren A. Walter, James Galbraith, Erik P. Hess   +6 more
openalex   +2 more sources

Metformin and Hepatocellular Carcinoma Risk Reduction in Diabetic Patients with Chronic Hepatitis C: Fact or Fiction? [PDF]

, 2023
M. Sacco, Davide Giuseppe Ribaldone, Giorgio Maria Saracco   +2 more
openalex   +1 more source

Association Between Liver Function Grade and Post‐Hepatectomy Liver Failure in Patients With Hepatocellular Carcinoma: A Latent Class Analysis

Annals of Gastroenterological Surgery, EarlyView.
We retrospectively analyzed clinical data from patients who underwent hepatectomy for hepatocellular carcinoma (HCC) using LCA‐based grading system. These findings provide a new risk stratification framework for the design of precision surgery to treat patients with HCC.
Ling Liu, Jintao Zheng, Ye Wang, Chenao Yang, Jiachen Zhang, Changku Jia   +5 more
wiley   +1 more source

Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions

Angewandte Chemie, EarlyView.
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan, Parrish Evers, Elexa Scott, John Paul Pezacki   +3 more
wiley   +2 more sources

Serum Bile Acids Are Useful Indicators of Intrahepatic Recurrence After Initial Curative Hepatectomy for Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Bile acids accumulation in hepatocytes causes liver damage and contributes to the development of hepatocellular carcinoma. However, the association between serum bile acid levels and postoperative intrahepatic recurrence in hepatocellular carcinoma remains unclear.
Tomoaki Bekki, Masahiro Ohira, Yuki Imaoka, Seiichi Simizu, Tomoyuki Abe, Shintaro Kuroda, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Hideki Ohdan   +9 more
wiley   +1 more source

Estimating the Cost-Effectiveness of One-Time Screening and Treatment for Hepatitis C in Korea

, 2017
Do Young Kim, Kwang‐Hyub Han, Byungyool Jun, Tae Hyun Kim, Sohee Park, Thomas Ward, Samantha Webster, Phil McEwan   +7 more
openalex   +2 more sources

Telaprevir for previously untreated chronic hepatitis C virus infection.

New England Journal of Medicine, 2011
I. Jacobson, J. Mchutchison, G. Dusheiko, A. Bisceglie, K. Reddy, N. Bzowej, P. Marcellin, A. Muir, P. Ferenci, R. Flisiak, J. George, M. Rizzetto, D. Shouval, R. Solá, R. Terg, E. Yoshida, N. Adda, L. Bengtsson, A. Sankoh, Tara L. Kieffer, S. George, R. Kauffman, S. Zeuzem, V. Phar   +23 more
semanticscholar   +1 more source