Results 201 to 210 of about 513,632 (295)
Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano+8 more
wiley +1 more source
The challenge of treating hepatitis C virus infection in children with comorbidities. [PDF]
Mogahed EA+4 more
europepmc +1 more source
Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy
Recent advances in the field of nucleic acid nuclear magnetic resonance (NMR) are presented. Stable isotope labeling protocols and new approaches to segmentally label nucleic acid with NMR‐active residues are summarized. The novel methods will have a strong impact on the future of nucleic acid NMR and the characterization of structure and dynamics of ...
Stefan Hilber+3 more
wiley +1 more source
Temporal trends and spatial patterns of Hepatitis C-related mortality in Brazil. [PDF]
Hyppolito EB+6 more
europepmc +1 more source
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima+11 more
wiley +1 more source
Autoantibodies to apolipoprotein A-I in hepatitis C virus infection: a role in disease progression? [PDF]
Bridge SH+10 more
europepmc +1 more source
Populations Addressed in Vaccines Approved via the European Medicines Agency
Therapeutic and prophylactic agents require robust evidence before patient use. Randomized controlled trials are essential for evaluating safety and efficacy but often exclude specific populations that are also targets for the intervention. This study assessed which populations are included in vaccine registration studies and/or addressed in label ...
Débora D. Gräf+3 more
wiley +1 more source