Results 201 to 210 of about 513,632 (295)

A serum exosomal microRNA‐based artificial intelligence diagnostic model for highly accurate detection of hepatocellular carcinoma

Cancer Communications, EarlyView.
Jin‐Seong Hwang, Sugi Lee, Gyeonghwa Kim, Hoibin Jeong, Kiyoon Kwon, Eunsun Jung, Yuna Roh, Taesang Son, Hana Lee, Moo‐Seung Lee, Kyoung‐Jin Oh, Hye Won Lee, Yu Rim Lee, Soo Young Park, Won Young Tak, Hyun Seung Ban, Hyun‐Soo Cho, Mi‐Young Son, Jang‐Seong Kim, Keun Hur, Dae‐Soo Kim, Tae‐Su Han   +21 more
wiley   +1 more source

Pharmacokinetics, Safety, and Skin Irritation and Sensitization Potential of Clascoterone Cream in Early‐Phase Clinical Study Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano, Milko Massimiliano Radicioni, Gerhard Garhöfer, Martina Cartwright, Markus Müller, Iris Kopeloff, Luigi Moro, Nicholas Squittieri, Alessandro Mazzetti   +8 more
wiley   +1 more source

The challenge of treating hepatitis C virus infection in children with comorbidities. [PDF]

Eur J Pediatr
Mogahed EA, Nabil N, Ghita H, Enayet A, El-Karaksy H.   +4 more
europepmc   +1 more source

Detection of genomic and intermediate replicative strands of hepatitis C virus in liver tissue by in situ hybridization.

, 1993
K T Nouri Aria, Richard Sallie, D. V. Sangar, Graeme Alexander, Heather M. Smith, J C Byrne, Bernard Portmann, A L Eddleston, Roger Williams   +8 more
openalex   +1 more source

Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy

ChemPlusChem, EarlyView.
Recent advances in the field of nucleic acid nuclear magnetic resonance (NMR) are presented. Stable isotope labeling protocols and new approaches to segmentally label nucleic acid with NMR‐active residues are summarized. The novel methods will have a strong impact on the future of nucleic acid NMR and the characterization of structure and dynamics of ...
Stefan Hilber, Solomon Kojo Attionu, Theodore Kwaku Dayie, Christoph Kreutz   +3 more
wiley   +1 more source

O14 Community prescribing of hepatitis C treatment: a mentorship and capacity building model to increase treatment uptake by targeted populations

Journal of Virus Eradication, 2017
S. Watkinson, L. Accadia, L. Coelli, G. Bartlett, T. Schulz, T. Shanahan, J. Sasadeusz   +6 more
doaj  

Temporal trends and spatial patterns of Hepatitis C-related mortality in Brazil. [PDF]

Rev Saude Publica
Hyppolito EB, Ramos Júnior AN, Ferreira AF, Dantas TO, Lima JMC, Silva TL, Pires Neto RDJ.   +6 more
europepmc   +1 more source

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima, Yukihiro Sanada, Shinya Otomo, Keiko Ogaki, Taiichi Wakiya, Noriki Okada, Yuta Hirata, Yasuharu Onishi, Yasunaru Sakuma, Yukiyo Wada, Akio Fujimura, Koichi Mizuta   +11 more
wiley   +1 more source

Autoantibodies to apolipoprotein A-I in hepatitis C virus infection: a role in disease progression? [PDF]

Front Immunol
Bridge SH, Pagano S, Lodge JK, Shawa IT, Marin-Crespo P, Cramp ME, Sheridan DA, Taylor-Robinson SD, Vuilleumier N, Neely RDG, Bassendine MF.   +10 more
europepmc   +1 more source

Populations Addressed in Vaccines Approved via the European Medicines Agency

Clinical Pharmacology &Therapeutics, EarlyView.
Therapeutic and prophylactic agents require robust evidence before patient use. Randomized controlled trials are essential for evaluating safety and efficacy but often exclude specific populations that are also targets for the intervention. This study assessed which populations are included in vaccine registration studies and/or addressed in label ...
Débora D. Gräf, Lukas Westphal, Jonathan Kimmelman, Christine E. Hallgreen   +3 more
wiley   +1 more source