Results 21 to 30 of about 589,018 (303)
Substitutions in SARS-CoV-2 Mpro Selected by Protease Inhibitor Boceprevir Confer Resistance to Nirmatrelvir
Viruses, 2023 Nirmatrelvir, which targets the SARS-CoV-2 main protease (Mpro), is the first-in-line drug for prevention and treatment of severe COVID-19, and additional Mpro inhibitors are in development.Karen Anbro Gammeltoft, Yuyong Zhou, Line Abildgaard Ryberg, Long V. Pham, Alekxander Binderup, Carlos Rene Duarte Hernandez, Anna Offersgaard, Ulrik Fahnøe, Günther Herbert Johannes Peters, Santseharay Ramirez, Jens Bukh, Judith Margarete Gottwein +11 moredoaj +1 more sourceIdentification of Novel Determinants of Neutralization Epitope Shielding for Hepatitis C Virus in Vitro
Proceedings, 2020 Epitope shielding is suggested as an important mechanism mediating the escape of hepatitis C virus (HCV) from host-neutralizing antibodies (nAb). [...]Garazi Peña Alzua, Anne Finne Pihl, Anna Falden Offersgaard, Rodrigo Velázquez-Moctezuma, Elias Honeroed Augestad, Ulrik Fahnøe, Christian Kjaerulff Mathiesen, Mansun Law, Jannick Prentoe, Jens Bukh, Judith Margarete Gottwein +10 moredoaj +1 more sourceChronic hepatitis C elimination prison initiative: HCV‐intensive test and treat, a whole prisoner population HCV test‐and‐treat program in England
Health Science Reports, 2023 Background and Aim Prison residents are at high risk for hepatitis C virus (HCV) infection. HCV test‐and‐treat initiatives within prisons provide an opportunity to engage with prison residents and achieve HCV micro‐elimination.Rachel Halford, Lee Christensen, Sean Cox, Julia Sheehan, Iain Brew, Mark Gillyon‐Powell, Georgia Threadgold, Éamonn O'Moore, Philip J. F. Troke, Andy Jones +9 moredoaj +1 more sourceEfficacy of Ion-Channel Inhibitors Amantadine, Memantine and Rimantadine for the Treatment of SARS-CoV-2 In Vitro
Viruses, 2021 We report the in vitro efficacy of ion-channel inhibitors amantadine, memantine and rimantadine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).Yuyong Zhou, Karen A. Gammeltoft, Andrea Galli, Anna Offersgaard, Ulrik Fahnøe, Santseharay Ramirez, Jens Bukh, Judith M. Gottwein +7 moredoaj +1 more sourceAssociation of TM6SF2 rs58542926 T/C gene polymorphism with hepatocellular carcinoma: a meta-analysis
BMC Cancer, 2019 Background Hepatocellular carcinoma (HCC) is the sixth-most common malignancy worldwide. Multiple previous studies have assessed the relationship between TM6SF2 gene polymorphism and the risk of developing HCC, with discrepant conclusions reached.Shan Tang, Jing Zhang, Ting-Ting Mei, Hai-Qing Guo, Xin-Huan Wei, Wen-Yan Zhang, Ya-Li Liu, Shan Liang, Zuo-Peng Fan, Li-Xia Ma, Wei Lin, Yi-Rong Liu, Li-Xia Qiu, Hai-Bin Yu +13 moredoaj +1 more sourceTracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection [PDF]
, 2007 Background. CD4+ T cell help is critical in maintaining antiviral immune responses and such help has been shown to be sustained in acute resolving hepatitis C.Paul Klenerman, GRÜNER N, Thimme, R., J. Tilman Gerlach, Weber, Jonathan N., Ulsenheimer, Axel, Helmut M. Diepolder, PFAFFEROT K, Semmo, N, Scriba, Thomas J, Silvana Gaudieri, Hans Nitschko, Grüner Norbert, SANTANTONIO, TERESA ANTONIA, Haberstroh, Anita, Diepolder Helmut M., Pfafferot, Katja, Jung, Maria-Christina, Rauch, A, Norbert Grüner, Andri Rauch, Scriba, T.J., Obermeier, M., Diepolder, HM, Pape Gerd R., Jonathan N Weber, Gaudieri Silvana, Malte H. J. Heeg, OBERMEIER M, Anita Haberstroh, SCHRAUT W, Jung, M-C, Gerd R Pape, Michaela Lucas, FIDLER S, RAUCH A, DAY C, Phillips, Rodney, Malte H.J. Heeg, Gaudieri, S., Maria-Christina Jung, Thimme Robert, Pape, Gerd R., Obermeier, Martin, Obermeier Martin, Day Cheryl, Obermeier, M, Rodney Phillips, Klenerman Paul, Heeg, MH, Martin Obermeier, Haberstroh, A., Day, C., Klenerman, Paul, Grüner, Norbert, Zachoval, R., Thimme, Robert, Baumert, Thomas F., Phillips, R., Gerlach, JT, Haberstroh Anita, Gerlach, J Tilman, Klenerman, P, Santantonio, T., ZACHOVAL R, Ulsenheimer, A., Nitschko, Hans, Lucas, Michaela, Nasser Semmo, Zachoval Reinhart, KLENERMAN P, Weber, J.N., Baumert Thomas F., Bowyer, S., Fidler, Sarah, Phillips Rodney, Haberstroh, A, Heeg Malte H.J., ULSENHEIMER A, Thomas F. Baumert, Baumert, TF, Diepolder, Helmut M, Axel Ulsenheimer, Thomas F Baumert, Gruener, N, Pfafferot, K, Pape, GR, Helmut M Diepolder, BAUMERT TF, Winfried Schraut, Jung, M.C., Zachoval, R, Gerlach, J.T., Thimme, R, Phillips, R, LUCAS M, Semmo, N., Heeg, Malte H. J., Semmo Nasser, HEEG MH, Gerlach J. Tilman, Nitschko Hans, HABERSTROH A, Santantonio Teresa, Robert Thimme, Grüner, N., Santantonio, T, Schraut Winfried, Klenerman, P., Pape, Gerd R, J. Tilman, Santantonio, Teresa, Scriba, Thomas J., Nitschko, H., Jung, MC, Jonathan N. Weber, Reinhart Zachoval, Scriba, TJ, NITSCHKO H, Lucas, M., Katja Pfafferot, Jung Maria-Christina, Fidler, S., Heeg, M., Schraut, Winfried, Malte H J Heeg, J Tilman Gerlach, Pfafferot Katja, Weber Jonathan N., Diepolder, H.M., Baumert, T.F., Gaudieri, S, Cheryl Day, GAUDIERI S, PAPE GR, Lucas, M, Fidler Sarah, WEBER JN, DIEPOLDER HM, Weber, Jonathan N, Schraut, W., Day, C, Ulsenheimer, A, Gerlach, J. Tilman, SEMMO N, Thomas J Scriba, Ulsenheimer Axel, Day, Cheryl, Lucas Michaela, PHILLIPS R, Diepolder, Helmut M., Pfafferott, K., Heeg, MHJ, Fidler, S, Rauch, A., Thomas J. Scriba, GERLACH JT, Gruner, N, Nitschko, H, Heeg, Malte H J, Gerd R. Pape, Sarah Fidler, Rauch Andri, Rauch, Andri, Baumert, Thomas F, Scriba Thomas J., Pape, G.R., Schraut, W, THIMME R, Semmo, Nasser, Weber, JN, JUNG MC, Teresa Santantonio, Gaudieri, Silvana, Zachoval, Reinhart, SCRIBA TJ +175 morecore +1 more sourceThe burden of hepatitis C virus in the world, China, India, and the United States from 1990 to 2019
Frontiers in Public Health, 2023 Background and aimHepatitis C virus infection can lead to an enormous health burden worldwide. Investigating the changes in HCV-related burden between different countries could provide inferences for disease management.Jia Yang, Jin-Lei Qi, Xiao-Xiao Wang, Xiao-He Li, Rui Jin, Bai-Yi Liu, Hui-Xin Liu, Hui-Ying Rao +7 moredoaj +1 more sourceA genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C [PDF]
, 2012 Background: To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.Jörg Bojunga, Raffaele Malinverni, Gerlach, Tilman J., Gerlach, Tilman J, Tilman J Gerlach, Swiss Hepatitis C Cohort Study Group,, Berg, T., Kutalik, Z., Stephanie Bibert, Christian M Lange, Geier, Andreas, Dufour, Jean-François Jacques, Thomas Berg, Malinverni, Raffaele, Regenass, S., Burgisser, Philippe, Regenass, Stephan, Badenhoop, Klaus, Bojunga, Jörg, Lange, Christian M, Dufour, J. F., Stephan Regenass, Gerlach, Tilman Joern, Swiss Hepatitis C Cohort Study Group, Bochud, P. Y., Dufour, Jean-Francois, Bojunga, J., Andreas Geier, Stefan Zeuzem, Negro, F., Cerny, A., Zoltan Kutalik, Lange, Christian, Pierre-Yves Bochud, Sarrazin, C., Tobias Müller, Sarrazin, Christoph, Lange, C. M., Cerny, Andreas, Kutalik, Zoltán, Bibert, S., Malinverni, R., Moradpour, Darius, Christoph Sarrazin, Burgisser, P., Gerlach, T. J., Moradpour, D., Bibert, Stephanie, Klaus Badenhoop, Zeuzem, S., Negro, Francesco, Müller, Tobias, Badenhoop, K., Andreas Cerny, Bochud, Pierre-Yves, Geier, A., Heim, M. H., Muller, T., Francesco Negro, Berg, Thomas, Markus H Heim, Heim, Markus H., Darius Moradpour, Jean-Francois Dufour, Philippe Burgisser, Heim, Markus H, Zeuzem, Stefan +66 morecore +1 more source
