Results 51 to 60 of about 477,291 (156)

Abl Tyrosine Kinase Regulates Hepatitis C Virus Entry

Frontiers in Microbiology, 2017
Abl is a central regulator of multiple cellular processes controlling actin dynamics, proliferation, and differentiation. Here, we showed that knockdown of Abl impaired hepatitis C virus (HCV) propagation.
Saehong Min, Saehong Min, Yun-Sook Lim, Dongjo Shin, Dongjo Shin, Chorong Park, Chorong Park, Jae-Bong Park, Seungtaek Kim, Marc P. Windisch, Soon B. Hwang, Soon B. Hwang   +11 more
doaj   +1 more source

Hepatitis B Virus Genotypes and Subgenotypes Circulating in Infected Residents in a Country with High Vaccination Rate

Viruses
Despite the availability of a vaccine against hepatitis B virus (HBV), this infection still causes public health problems, particularly in susceptible populations.
Carolina Silva, Diogo Ramos, Miriam Quina, Elizabeth Pádua   +3 more
doaj   +1 more source

Differential Regulation of Lipoprotein and Hepatitis C Virus Secretion by Rab1b

Cell Reports, 2017
Summary: Secretory cells produce diverse cargoes, yet how they regulate concomitant secretory traffic remains insufficiently explored. Rab GTPases control intracellular vesicular transport.
Constantin N. Takacs, Ursula Andreo, Viet Loan Dao Thi, Xianfang Wu, Caroline E. Gleason, Michelle S. Itano, Gabriella S. Spitz-Becker, Rachel L. Belote, Brenna R. Hedin, Margaret A. Scull, Charles M. Rice, Sanford M. Simon   +11 more
doaj   +1 more source

T cell receptor usage and epitope specificity amongst CD8+ and CD4+ SARS-CoV-2-specific T cells

Frontiers in Immunology
IntroductionThe coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has highlighted the critical importance of understanding protective long-lasting immune responses.
Ulrik Fahnøe, Ulrik Fahnøe, Ulrik Fahnøe, Shan Feng, Shan Feng, Shan Feng, Alexander P. Underwood, Alexander P. Underwood, Alexander P. Underwood, Kivin Jacobsen, Amir Ameri, Thomas H. Blicher, Christina S. Sølund, Christina S. Sølund, Christina S. Sølund, Brad R. Rosenberg, Liselotte Brix, Nina Weis, Nina Weis, Jens Bukh, Jens Bukh, Jens Bukh   +21 more
doaj   +1 more source

HCV and HBV prevalence based on home blood self-sampling and screening history in the general population in 2016: contribution to the new French screening strategy

BMC Infectious Diseases, 2019
Background The advent of effective direct-acting antivirals (DAAs), has prompted an assessment of the French Hepatitis C virus (HCV) screening strategy, which historically targeted high-risk groups. One of the options put forward is the implementation of
Cécile Brouard, Leïla Saboni, Arnaud Gautier, Stéphane Chevaliez, Delphine Rahib, Jean-Baptiste Richard, Francis Barin, Christine Larsen, Cécile Sommen, Josiane Pillonel, Elisabeth Delarocque-Astagneau, Nathalie Lydié, Florence Lot, the 2016 Health Barometer Group   +13 more
doaj   +1 more source

Hepatitis C [PDF]

Journal of Midwifery & Women's Health, 2017
openaire   +4 more sources

In Vivo Determinants of Hepatitis C Virus Adaptation and Escape From Neutralizing Antibody AR5ASummaryWhat You Need to Know

Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: Mechanisms of hepatitis C virus (HCV) adaptation and escape from broadly neutralizing antibodies (bNAbs) have been primarily studied in vitro.
Rodrigo Velázquez-Moctezuma, Rani Burm, Lieven Verhoye, Laura Collignon, Kenn Holmbeck, Erick Giang, Mansun Law, Jens Bukh, Philip Meuleman, Jannick Prentoe   +9 more
doaj   +1 more source

The effects of low-dose IL-2 on Th17/Treg cell imbalance in primary biliary cholangitis mouse models

BMC Gastroenterology
Background/aims Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease. The imbalance of Th17/Treg cells has been reported in PBC patients. Low-dose IL-2 can alleviate disease severity through modulating CD4 + T cell subsets in patients
Zilong Wang, Zhicheng Liu, Jiarui Zheng, Linxiang Huang, Rui Jin, Xiaoxiao Wang, Dongbo Chen, Yandi Xie, Bo Feng   +8 more
doaj   +1 more source

GSDMD induces hepatocyte pyroptosis to trigger alcoholic hepatitis through modulating mitochondrial dysfunction

Cell Division
Background Mechanisms and consequences of Gasdermin D (GSDMD) activation in alcoholic hepatitis (AH) are unclear. In the present study, we investigated whether GSDMD induces hepatocyte pyroptosis by regulating mitochondrial dysfunction in AH.
Yandi Xie, Zilong Wang, Guangjun Song, Hui Ma, Bo Feng   +4 more
doaj   +1 more source

Long-Term Real-World Outcomes of Tenofovir Alafenamide in Chronic Hepatitis B: Detailed Analysis of Treatment-Naive and Experienced Patients

The Korean Journal of Gastroenterology
Background/Aims: This study assessed the long-term efficacy and safety of tenofovir alafenamide (TAF) in real-world settings. Methods: Patients who were candidates for TAF treatment and were followed up at 12-week intervals over 192 weeks were enrolled ...
Yu-Xuan Song, Guang-Jun Song, Hui Ma, Bo Feng, Yan-Di Xie   +4 more
doaj   +1 more source