Results 51 to 60 of about 20,131,715 (394)

Seroprevalensi Hepatitis C pada Populasi Perkotaan dan Perdesaan di Indonesia Tahun 2013: Kajian Determinan Sosiodemografi, Lingkungan, Pejamu, dan Komorbiditas (Analisis Lanjut Riskesdas 2013) [PDF]

open access: yes, 2017
Hepatitis C is an infectious disease caused by RNA virus that is often asymptomatic and can lead into serious complications such as liver cancer. It remains one of major public health issues in several developing countries.
Dany, F. (Frans), Handayani, S. (Sarwo)
core   +1 more source

Analysis of Hepatitis C Virus Particle Heterogeneity in Immunodeficient Human Liver Chimeric fah-/- MiceSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2017
Background & Aims: Hepatitis C virus (HCV) is a leading cause of chronic liver diseases and the most common indication for liver transplantation in the United States.
Ursula Andreo   +10 more
doaj   +1 more source

The predictive value of PD‐L1 expression in patients with advanced hepatocellular carcinoma treated with PD‐1/PD‐L1 inhibitors: A systematic review and meta‐analysis

open access: yesCancer Medicine, 2023
Background and Aim Programmed death 1 (PD‐1) and programmed death ligand 1 (PD‐L1) inhibitors have transformed the treatment landscape of advanced hepatocellular carcinoma (HCC), but consistent responses are not observed in all patients, and prognostic ...
Yao Yang   +6 more
doaj   +1 more source

High-Titer Hepatitis C Virus Production in a Scalable Single-Use High Cell Density Bioreactor

open access: yesVaccines, 2022
Hepatitis C virus (HCV) infections pose a major public health burden due to high chronicity rates and associated morbidity and mortality. A vaccine protecting against chronic infection is not available but would be important for global control of HCV ...
Anna Offersgaard   +9 more
doaj   +1 more source

Hepatitis induced by noni juice from Morinda citrifolia: A rare cause of hepatotoxicity or the tip of the iceberg? [PDF]

open access: yes, 2006
A 24-year-old female patient presented to her community hospital with mild elevations of serum transaminase and bilirubin levels. Because of multiple sclerosis, she was treated with interferon beta-la for 6 weeks.
Diebold, J.   +3 more
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Characteristic gene expression in the liver monocyte-macrophage-DC system is associated with the progression of fibrosis in NASH

open access: yesFrontiers in Immunology, 2023
BackgroundThe monocyte-macrophage-dendritic cell (DC) (MMD) system exerts crucial functions that may modulate fibrogenesis in nonalcoholic steatohepatitis (NASH).
Xiaoxiao Wang   +12 more
doaj   +1 more source

Novel HCV Genotype 4d Infectious Systems and Assessment of Direct-Acting Antivirals and Antibody Neutralization

open access: yesViruses, 2022
Hepatitis C virus (HCV) genotype 4 is highly prevalent in the Middle East and parts of Africa. Subtype 4d has recently spread among high-risk groups in Europe.
Long V. Pham   +9 more
doaj   +1 more source

Global epidemiology of hepatitis C virus infection: An up-date of the distribution and circulation of hepatitis C virus genotypes

open access: yesWorld Journal of Gastroenterology, 2016
AIM To review Hepatitis C virus (HCV) prevalence and genotypes distribution worldwide. METHODS We conducted a systematic study which represents one of the most comprehensive effort to quantify global HCV epidemiology, using the best available published ...
A. Petruzziello   +4 more
semanticscholar   +1 more source

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