Results 61 to 70 of about 19,295,259 (301)

Hepatitis C and ageing: a community brief [PDF]

, 2014
Executive summary: An estimated 226,700 people in Australia are living with chronic hepatitis C. While the numbers of people estimated to have been infected with hepatitis C has reduced over the past 15 years, the number of people with hepatitis C ...
Jacqui Richmond, Jack Wallace
core  

Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism [PDF]

, 2003
Background. Tumor necrosis factor-alpha (TNF-alpha) is involved in the pathogenesis of chronic active hepatitis C. Polymorphisms in the promoter region of the TNF-alpha gene can alter the TNF-alpha expression and modify the host immune response.
Konig, A., Folwaczny, Christian, Schmidt, F., Simperl, C., Schaefer, M., Torok, P., Glas, J., Schiemann, Uwe, Martin, K.   +8 more
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Influence of IL-10RA and IL-22 polymorphisms on outcome of hepatitis C virus infection.

, 2007
BACKGROUND: Two receptor chains, IL-10RA and IL-10RB, are known to mediate the functions of interleukin-10 (IL-10), which has been shown to be involved in the progression of persistent hepatitis C virus (HCV) infection. Little information is available on
Thursz, Mark, Hill, Adrian V, Hill, Adrian, Knapp, S, Zhang, Lyna, Thomas, Howard C, Yee, LJ, Thomas, HC, Hennig, Branwen J, Wright, Mark, Yee, Leland J, Hennig, BJ, Frodsham, Angela J, Frodsham, AJ, Zhang, L, Wright, M, Hellier, Simon, Thursz, M, Knapp, Susanne, Hellier, S, Hill, AV   +20 more
core   +1 more source

Soluble serum CD81 is elevated in patients with chronic hepatitis C and correlates with alanine aminotransferase serum activity [PDF]

, 2012
Aim: Cellular CD81 is a well characterized hepatitis C virus (HCV) entry factor, while the relevance of soluble exosomal CD81 in HCV pathogenesis is poorly defined.
Kronenberger Bernd, Stefan Zeuzem, Reichert, David, Kronenberger, Bernd, Martinez, Yolanda, Martinez Yolanda, Bernd Kronenberger, Susser, Simone, Sarrazin, Christoph, Herrmann Eva, Susser Simone, Zeuzem Stefan, Piiper, Albrecht, Christoph Sarrazin, Simone Susser, Reichert David, Piiper Albrecht, Herrmann, Eva, Sarrazin Christoph, Martin-Walter Welker, Welker Martin-Walter, Albrecht Piiper, Eva Herrmann, Welker, Martin-Walter, David Reichert, Zeuzem, Stefan, Yolanda Martinez   +26 more
core   +2 more sources

An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals

Scientific Reports
Rapidly waning immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires continued global access to affordable vaccines. Globally, inactivated SARS-CoV-2 vaccines have been widely used during the SARS-CoV-2 pandemic.
Anna Offersgaard, Carlos R. Duarte Hernandez, Yuyong Zhou, Zhe Duan, Karen Anbro Gammeltoft, Katrine T. Hartmann, Ulrik Fahnøe, Pavel Marichal-Gallardo, Garazi Peña Alzua, Alexander P. Underwood, Christina Sølund, Nina Weis, Jesper Hansen Bonde, Jan P. Christensen, Gabriel K. Pedersen, Henrik Elvang Jensen, Kenn Holmbeck, Jens Bukh, Judith Margarete Gottwein   +18 more
doaj   +1 more source

A Novel Nomogram to Predict Prolonged Survival After Hepatectomy in Repeat Recurrent Hepatocellular Carcinoma

Frontiers in Oncology, 2021
Background: Repeat hepatectomy is an important treatment for patients with repeat recurrent hepatocellular carcinoma (HCC).Methods: This study was a multicenter retrospective analysis of 1,135 patients who underwent primary curative liver resection for ...
Qiongxuan Fang, Ruifeng Yang, Dongbo Chen, Ran Fei, Pu Chen, Kangjian Deng, Jie Gao, Weijia Liao, Hongsong Chen   +8 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Distinct cytokine patterns in Occult Hepatitis C and Chronic Hepatitis C Virus Infection [PDF]

, 2011
Background & Aim: The immunopathogenesis of chronic hepatitis C virus (HCV) infection is a matter of great controversy. The imbalance of T-helper lymphocyte cell cytokine production was believed to play an important pathogenic role in ...
Nashwa Abousamra, Azza Azza Abdel-Aziz, Mona Elhadidy, Mohamed Abd-elmaksoud, Yahia Gad, Nasser Mousa   +5 more
core  

Diagnoses of, and deaths from, severe liver disease due to hepatitis C in England between 2000 and 2005 estimated using multiple data sources. [PDF]

, 2008
Matching individuals reported to a sentinel surveillance scheme for hepatitis C between 2000 and 2005 to individuals with a hospital episode for hepatitis C-related liver disease in the same hospitals, we estimated that the number of cases of hepatitis C-
Mann, AG, Balogun, MA, Brant, LJ, Costella, A, Harris, HE, Ramsay, ME, A. COSTELLA, H. E. HARRIS, M. A. BALOGUN, L. J. BRANT, M. E. RAMSAY, A. G. MANN   +11 more
core   +1 more source